Advances in progressive supranuclear palsy: new diagnostic criteria, biomarkers, and therapeutic approaches

• Published in: Lancet neurology Vol. 16; no. 7; pp. 552 - 563
• Main Authors: Boxer, Adam L, Yu, Jin-Tai, Golbe, Lawrence I, Litvan, Irene, Lang, Anthony E, Höglinger, Günter U
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.07.2017; Elsevier Limited
• Subjects: Alzheimer's disease; Basal ganglia; Biomarkers; Brain diseases; Brain research; Central nervous system diseases; Clinical trials; Encephalopathy; Humans; Medical diagnosis; Motor task performance; Movement disorders; Neurodegeneration; Neurodegenerative diseases; Neurology; Neuropathology; Paralysis; Pathology; Progressive supranuclear palsy; Supranuclear Palsy, Progressive - diagnosis; Supranuclear Palsy, Progressive - therapy; Tau protein; Therapeutic applications

Progressive supranuclear palsy (PSP), previously believed to be a common cause of atypical parkinsonism, is now recognised as a range of motor and behavioural syndromes that are associated with a characteristic 4-repeat tau neuropathology. New research criteria that recognise early presentations of...