The relationship between platelet reactivity and infarct-related artery patency in patients presenting with a ST-elevation myocardial infarction

• Published in: Thrombosis and haemostasis Vol. 106; no. 2; p. 331
• Main Authors: Breet, Nicoline J, van Werkum, Jochem W, Bouman, Heleen J, Kelder, Johannes C, Hackeng, Christian M, ten Berg, Jurriën M
• Format: Journal Article
• Language: English
• Published: Germany 01.08.2011
• Subjects: Adenosine Diphosphate - pharmacology; Aged; Angioplasty, Balloon, Coronary; Arachidonic Acid - pharmacology; Cohort Studies; Coronary Angiography; Female; Humans; Leukocyte Count; Male; Middle Aged; Myocardial Infarction - blood; Myocardial Infarction - diagnostic imaging; Myocardial Infarction - physiopathology; Myocardial Infarction - therapy; Platelet Activation - drug effects; Prospective Studies; Risk Factors; Treatment Outcome; Vascular Patency

Both heightened platelet reactivity and an occluded infarct related artery (IRA) on initial angiography and at the time of primary percutaneous coronary intervention (PCI) are associated with a worsened clinical outcome in patients with ST-elevation myocardial infarction (STEMI). However, the relati...