Effect of Sterilization on the Dimensional and Mechanical Behavior of Polylactic Acid Pieces Produced by Fused Deposition Modeling

To successfully implement additive manufacturing (AM) techniques for custom medical device (MD) production with low-cost resources, it is imperative to understand the effect of common and affordable sterilization processes, such as formaldehyde or steam sterilization, on pieces manufactured by AM. I...

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Published inPolymers Vol. 15; no. 15; p. 3317
Main Authors Garnica-Bohórquez, Israel, Güiza-Argüello, Viviana R, López-Gualdrón, Clara I
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 01.08.2023
MDPI
Subjects
3-D printers
additive manufacturing
Analysis
Back surgery
Chemical processes
Deposition
Developing countries
Dimensional stability
Formaldehyde
Fused deposition modeling
Lactic acid
LDCs
Low income groups
Manufacturing
material extrusion (MEX)
Mechanical properties
Medical device industry
Medical devices
Medical equipment
Methods
Orthopedics
Polylactic acid
polylactic acid (PLA)
Polymers
Software
Sterilization
Surgeons
Surgical instruments
Temperature
Titanium alloys
Colombia
United States > US
Netherlands
polylactic acid (PLA)
additive manufacturing
material extrusion (MEX)
sterilization
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Abstract To successfully implement additive manufacturing (AM) techniques for custom medical device (MD) production with low-cost resources, it is imperative to understand the effect of common and affordable sterilization processes, such as formaldehyde or steam sterilization, on pieces manufactured by AM. In this way, the performance of low-risk MDs, such as biomodels and surgical guides, could be assessed for complying with safety, precision, and MD delivery requirements. In this context, the aim of the present work was to evaluate the effect of formaldehyde and steam sterilization on the dimensional and mechanical stability of standard polylactic acid (PLA) test pieces produced by fused deposition modeling (FDM). To achieve this, PLA samples were sterilized according to the sterilization protocol of a public hospital in the city of Bucaramanga, Colombia. Significant changes regarding mechanical and dimensional properties were found as a function of manufacturing parameters. This research attempts to contribute to the development of affordable approaches for the fabrication of functional and customized medical devices through AM technologies, an issue of particular interest for low- and middle-income countries.
AbstractList To successfully implement additive manufacturing (AM) techniques for custom medical device (MD) production with low-cost resources, it is imperative to understand the effect of common and affordable sterilization processes, such as formaldehyde or steam sterilization, on pieces manufactured by AM. In this way, the performance of low-risk MDs, such as biomodels and surgical guides, could be assessed for complying with safety, precision, and MD delivery requirements. In this context, the aim of the present work was to evaluate the effect of formaldehyde and steam sterilization on the dimensional and mechanical stability of standard polylactic acid (PLA) test pieces produced by fused deposition modeling (FDM). To achieve this, PLA samples were sterilized according to the sterilization protocol of a public hospital in the city of Bucaramanga, Colombia. Significant changes regarding mechanical and dimensional properties were found as a function of manufacturing parameters. This research attempts to contribute to the development of affordable approaches for the fabrication of functional and customized medical devices through AM technologies, an issue of particular interest for low- and middle-income countries.
Audience Academic
Author Garnica-Bohórquez, Israel
Güiza-Argüello, Viviana R
López-Gualdrón, Clara I
AuthorAffiliation 1 Industrial Design Department, Universidad Industrial de Santander, Bucaramanga 680002, Colombia; clalogu@uis.edu.co
2 Metallurgical Engineering and Materials Science Department, Universidad Industrial de Santander, Bucaramanga 680002, Colombia; vivragui@uis.edu.co
AuthorAffiliation_xml – name: 1 Industrial Design Department, Universidad Industrial de Santander, Bucaramanga 680002, Colombia; clalogu@uis.edu.co
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  fullname: Garnica-Bohórquez, Israel
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  givenname: Viviana R
  orcidid: 0000-0003-0050-1887
  surname: Güiza-Argüello
  fullname: Güiza-Argüello, Viviana R
  organization: Metallurgical Engineering and Materials Science Department, Universidad Industrial de Santander, Bucaramanga 680002, Colombia
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  givenname: Clara I
  surname: López-Gualdrón
  fullname: López-Gualdrón, Clara I
  organization: Industrial Design Department, Universidad Industrial de Santander, Bucaramanga 680002, Colombia
BackLink https://www.ncbi.nlm.nih.gov/pubmed/37571211$$D View this record in MEDLINE/PubMed
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Issue 15
Keywords polylactic acid (PLA)
additive manufacturing
material extrusion (MEX)
sterilization
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Snippet To successfully implement additive manufacturing (AM) techniques for custom medical device (MD) production with low-cost resources, it is imperative to...
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StartPage 3317
SubjectTerms 3-D printers
additive manufacturing
Analysis
Back surgery
Chemical processes
Deposition
Developing countries
Dimensional stability
Formaldehyde
Fused deposition modeling
Lactic acid
LDCs
Low income groups
Manufacturing
material extrusion (MEX)
Mechanical properties
Medical device industry
Medical devices
Medical equipment
Methods
Orthopedics
Polylactic acid
polylactic acid (PLA)
Polymers
Software
Sterilization
Surgeons
Surgical instruments
Temperature
Titanium alloys
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Title Effect of Sterilization on the Dimensional and Mechanical Behavior of Polylactic Acid Pieces Produced by Fused Deposition Modeling
URI https://www.ncbi.nlm.nih.gov/pubmed/37571211
https://www.proquest.com/docview/2849089397/abstract/
https://search.proquest.com/docview/2850307757
https://pubmed.ncbi.nlm.nih.gov/PMC10422276
https://doaj.org/article/ea5a771698e64b1b948d05475556758d
Volume 15
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