Oroxylum indicum root bark extract prevents doxorubicin-induced cardiac damage by restoring redox balance

• Published in: Journal of ayurveda and integrative medicine Vol. 10; no. 3; pp. 159 - 165
• Main Authors: Menon, Seema, Lawrence, Lincy, Sivaram, Vipin P., Padikkala, Jose
• Format: Journal Article
• Language: English
• Published: United States Elsevier B.V 01.07.2019; Elsevier Limited; Elsevier
• Subjects: Acids; Antioxidants; Ayurvedic medicine; Cancer therapies; Cardioprotection; Chemotherapy; Chromatography; Doxorubicin; Free radicals; Heart; HPTLC; Inflammation; Laboratories; Lipid peroxidation; Original s- Experimental; Oroxylum indicum Vent; Oxidative stress; Phytochemicals; Proteins; Rheumatoid arthritis; Mumbai India; India; Cardioprotection; Oroxylum indicum Vent; Doxorubicin; HPTLC

Oroxylum indicum Vent., a Dasamula plant used in Ayurveda possesses antioxidant properties. To evaluate the cardioprotective effect of 70% methanolic extract of O. indicum Vent. root bark (OIM) against doxorubicin induced cardiomyopathy in female Sprague Dawley rats. Cardiotoxicity was induced by in...