Gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA suggest prolonged gastrointestinal infection

• Published in: Med (New York, N.Y. : Online) Vol. 3; no. 6; pp. 371 - 387.e9
• Main Authors: Natarajan, Aravind, Zlitni, Soumaya, Brooks, Erin F., Vance, Summer E., Dahlen, Alex, Hedlin, Haley, Park, Ryan M., Han, Alvin, Schmidtke, Danica T., Verma, Renu, Jacobson, Karen B., Parsonnet, Julie, Bonilla, Hector F., Singh, Upinder, Pinsky, Benjamin A., Andrews, Jason R., Jagannathan, Prasanna, Bhatt, Ami S.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 10.06.2022
• Subjects: Clinical Advances; Communicable Diseases; COVID-19; COVID-19 - diagnosis; COVID-19 Testing; fecal RNA; Feces; Gastrointestinal Diseases - diagnosis; gastrointestinal infection; Humans; Lung; RNA, Viral - genetics; SARS-CoV-2; SARS-CoV-2 - genetics; viral shedding; COVID-19; SARS-CoV-2; gastrointestinal infection; Translation to patients; viral shedding; fecal RNA

COVID-19 manifests with respiratory, systemic, and gastrointestinal (GI) symptoms.1, SARS-CoV-2 RNA is detected in respiratory and fecal samples, and recent reports demonstrate viral replication in both the lung and intestinal tissue.2–4 Although much is known about early fecal RNA shedding, little...