Activation-independent, antibody-mediated removal of GPVI from circulating human platelets: development of a novel NOD/SCID mouse model to evaluate the in vivo effectiveness of anti–human platelet agents - Boylan, Brian; Berndt, Michael C.; Kahn, Mark L.; Newman, Peter J. (Blood, 2006)
Keywords: Animals; Antibodies, Monoclonal - pharmacology; Antibodies, Monoclonal - therapeutic use; Biological and medical sciences; Blood Platelets - drug effects; Blood. Blood coagulation. Reticuloendothelial system; Cell Survival - drug effects; Hemostasis, Thrombosis, and Vascular Biology; Humans; Medical sciences; Mice; Mice, Inbred NOD; Mice, SCID; Models, Animal; Pharmacology. Drug treatments; Platelet Activation - drug effects; Platelet Aggregation - drug effects; Platelet Aggregation Inhibitors - pharmacology; Platelet Membrane Glycoproteins - immunology; Human; In vivo; Animal model; Platelet; Platelet function; NOD/SCID mouse; Glycoprotein VI; Monoclonal antibody; Antiplatelet agent