Multimodal Strategies to Fight Obesity: Research on Tailored Therapies Based on Natural and Synthetic Compounds for Prevention, Management and Treatment

In the past 50 years, the global prevalence of obesity and overweight has tripled, reaching pandemic proportions and blatantly representing an urgent problem for public health [...].

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Bibliographic Details
Published inInternational journal of molecular sciences Vol. 24; no. 12; p. 10105
Main Authors D'Anneo, Antonella, Lauricella, Marianna
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 01.06.2023
MDPI
Subjects
Adipocytes
Antioxidants
B cells
Bioavailability
Body fat
Cardiovascular disease
Chronic illnesses
Diabetes
Glucose
Humans
Hyaluronic acid
Hypoxia
Inflammation
Kinases
Lipids
Metabolism
n/a
Obesity
Obesity - epidemiology
Obesity - prevention & control
Overweight - epidemiology
Polyphenols
Prevalence
Prevention
Public Health
Resveratrol
Type 2 diabetes
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Abstract In the past 50 years, the global prevalence of obesity and overweight has tripled, reaching pandemic proportions and blatantly representing an urgent problem for public health [...].
AbstractList In the past 50 years, the global prevalence of obesity and overweight has tripled, reaching pandemic proportions and blatantly representing an urgent problem for public health [...]
Audience Academic
Author D'Anneo, Antonella
Lauricella, Marianna
AuthorAffiliation 2 Department of Biomedicine, Neurosciences and Advanced Diagnostics (BIND), Institute of Biochemistry, University of Palermo, 90127 Palermo, Italy
1 Laboratory of Biochemistry, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, 90127 Palermo, Italy
AuthorAffiliation_xml – name: 1 Laboratory of Biochemistry, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, 90127 Palermo, Italy
– name: 2 Department of Biomedicine, Neurosciences and Advanced Diagnostics (BIND), Institute of Biochemistry, University of Palermo, 90127 Palermo, Italy
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  givenname: Antonella
  orcidid: 0000-0002-1785-8236
  surname: D'Anneo
  fullname: D'Anneo, Antonella
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– sequence: 2
  givenname: Marianna
  orcidid: 0000-0002-0157-3834
  surname: Lauricella
  fullname: Lauricella, Marianna
  organization: Department of Biomedicine, Neurosciences and Advanced Diagnostics (BIND), Institute of Biochemistry, University of Palermo, 90127 Palermo, Italy
BackLink https://www.ncbi.nlm.nih.gov/pubmed/37373254$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1194/jlr.R021089
10.1111/j.1467-789X.2004.00144.x
10.3390/ijms23052890
10.3389/fimmu.2019.01587
10.3390/ijms232113439
10.3390/ijms24054730
10.1016/j.biopha.2018.12.108
10.1016/j.exger.2022.111798
10.1016/j.fct.2018.05.010
10.1002/dmrr.3203
10.1038/sj.ijo.0803036
10.3390/ijms20092358
10.3390/ijms24044145
10.1126/science.164.3880.719
10.1016/S1098-3597(99)90002-9
10.1152/physrev.00017.2012
10.3390/ijms231911843
10.1079/NRR200371
10.1038/s41580-018-0093-z
10.3390/ijms24043467
10.1016/j.jff.2018.02.001
10.3390/nu12092499
10.3390/ijms21176181
10.1210/me.2008-0183
10.1146/annurev-physiol-060721-092930
10.3390/ijms24076621
10.3390/ijms222111832
10.1038/s41574-019-0176-8
10.3390/molecules26144328
10.3390/nu14235099
10.3390/ijms24032310
10.1152/ajpcell.00379.2020
10.1016/j.jdiacomp.2021.108026
10.1038/oby.2006.252
10.1093/advances/nmy055
10.3390/ijms23179867
10.3390/antiox11071313
10.3390/ijms231810465
10.3390/ijms23137011
10.1038/s41418-022-01062-4
10.1186/s12889-018-5392-y
10.3390/antiox8100422
10.7150/ijms.27669
10.1684/ecn.2018.0415
10.3390/ijms24065672
10.3390/antiox11020363
10.3390/ijms23020956
10.1016/j.cell.2021.12.016
10.1055/s-0044-101752
10.3389/fphar.2020.621955
10.3390/ijms24065419
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References ref_50
Livesey (ref_25) 2003; 16
Ghaben (ref_12) 2019; 20
Carrageta (ref_42) 2018; 43
Cawthorn (ref_48) 2012; 53
ref_11
Mahmoud (ref_22) 2019; 111
ref_52
Fornai (ref_41) 2021; 11
ref_19
ref_18
Quines (ref_24) 2018; 118
Karczewski (ref_8) 2018; 29
Caballero (ref_2) 2019; 10
DiNicolantonio (ref_27) 2017; 114
Ishaq (ref_28) 2022; 163
ref_21
ref_20
Golozoubova (ref_44) 2006; 14
Olney (ref_23) 1969; 164
ref_29
ref_26
Liu (ref_13) 2019; 10
Zaragoza (ref_45) 2005; 29
Santaniello (ref_51) 2018; 15
ref_36
ref_35
Panahi (ref_37) 2018; 68
ref_34
ref_33
ref_32
ref_31
Keophiphath (ref_17) 2009; 23
ref_30
ref_38
Trayhurn (ref_14) 2013; 93
Terzo (ref_39) 2021; 35
Kawai (ref_9) 2021; 320
Conway (ref_3) 2004; 5
Khaodhiar (ref_5) 1999; 2
ref_47
ref_46
ref_43
ref_40
(ref_6) 2019; 35
ref_49
(ref_1) 2019; 15
Sakers (ref_15) 2022; 185
Marcelin (ref_16) 2022; 84
ref_4
ref_7
Hildebrandt (ref_10) 2023; 30
References_xml – volume: 53
  start-page: 227
  year: 2012
  ident: ref_48
  article-title: Adipose Tissue Stem Cells Meet Preadipocyte Commitment: Going Back to the Future
  publication-title: J. Lipid Res.
  doi: 10.1194/jlr.R021089
  contributor:
    fullname: Cawthorn
– volume: 5
  start-page: 145
  year: 2004
  ident: ref_3
  article-title: Obesity as a Disease: No Lightweight Matter
  publication-title: Obes. Rev.
  doi: 10.1111/j.1467-789X.2004.00144.x
  contributor:
    fullname: Conway
– ident: ref_7
  doi: 10.3390/ijms23052890
– volume: 10
  start-page: 1587
  year: 2019
  ident: ref_13
  article-title: Tissue Immune Cells Fuel Obesity-Associated Inflammation in Adipose Tissue and Beyond
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2019.01587
  contributor:
    fullname: Liu
– ident: ref_43
  doi: 10.3390/ijms232113439
– ident: ref_21
  doi: 10.3390/ijms24054730
– volume: 111
  start-page: 503
  year: 2019
  ident: ref_22
  article-title: Obesity: Pathophysiology, Monosodium Glutamate-Induced Model and Anti-Obesity Medicinal Plants
  publication-title: Biomed. Pharmacother.
  doi: 10.1016/j.biopha.2018.12.108
  contributor:
    fullname: Mahmoud
– volume: 114
  start-page: 303
  year: 2017
  ident: ref_27
  article-title: Good Fats versus Bad Fats: A Comparison of Fatty Acids in the Promotion of Insulin Resistance, Inflammation, and Obesity
  publication-title: Mo. Med.
  contributor:
    fullname: DiNicolantonio
– volume: 163
  start-page: 111798
  year: 2022
  ident: ref_28
  article-title: Palmitate Induces DNA Damage and Senescence in Human Adipocytes in Vitro That Can Be Alleviated by Oleic Acid but Not Inorganic Nitrate
  publication-title: Exp. Gerontol.
  doi: 10.1016/j.exger.2022.111798
  contributor:
    fullname: Ishaq
– volume: 118
  start-page: 168
  year: 2018
  ident: ref_24
  article-title: (P-ClPhSe)2 Stabilizes Metabolic Function in a Rat Model of Neuroendocrine Obesity Induced by Monosodium Glutamate
  publication-title: Food Chem. Toxicol.
  doi: 10.1016/j.fct.2018.05.010
  contributor:
    fullname: Quines
– volume: 35
  start-page: e3203
  year: 2019
  ident: ref_6
  article-title: Childhood Obesity: Aetiology, Comorbidities, and Treatment
  publication-title: Diabetes Metab. Res. Rev.
  doi: 10.1002/dmrr.3203
– volume: 29
  start-page: 1402
  year: 2005
  ident: ref_45
  article-title: Influence of a Selective Histamine H3 Receptor Antagonist on Hypothalamic Neural Activity, Food Intake and Body Weight
  publication-title: Int. J. Obes.
  doi: 10.1038/sj.ijo.0803036
  contributor:
    fullname: Zaragoza
– ident: ref_11
  doi: 10.3390/ijms20092358
– ident: ref_20
  doi: 10.3390/ijms24044145
– volume: 164
  start-page: 719
  year: 1969
  ident: ref_23
  article-title: Brain Lesions, Obesity, and Other Disturbances in Mice Treated with Monosodium Glutamate
  publication-title: Science
  doi: 10.1126/science.164.3880.719
  contributor:
    fullname: Olney
– volume: 2
  start-page: 17
  year: 1999
  ident: ref_5
  article-title: Obesity and Its Comorbid Conditions
  publication-title: Clin. Cornerstone
  doi: 10.1016/S1098-3597(99)90002-9
  contributor:
    fullname: Khaodhiar
– volume: 93
  start-page: 1
  year: 2013
  ident: ref_14
  article-title: Hypoxia and Adipose Tissue Function and Dysfunction in Obesity
  publication-title: Physiol. Rev.
  doi: 10.1152/physrev.00017.2012
  contributor:
    fullname: Trayhurn
– ident: ref_19
  doi: 10.3390/ijms231911843
– volume: 16
  start-page: 163
  year: 2003
  ident: ref_25
  article-title: Health Potential of Polyols as Sugar Replacers, with Emphasis on Low Glycaemic Properties
  publication-title: Nutr. Res. Rev.
  doi: 10.1079/NRR200371
  contributor:
    fullname: Livesey
– volume: 20
  start-page: 242
  year: 2019
  ident: ref_12
  article-title: Adipogenesis and Metabolic Health
  publication-title: Nat. Rev. Mol. Cell Biol.
  doi: 10.1038/s41580-018-0093-z
  contributor:
    fullname: Ghaben
– ident: ref_40
  doi: 10.3390/ijms24043467
– volume: 43
  start-page: 84
  year: 2018
  ident: ref_42
  article-title: Anti-Obesity Potential of Natural Methylxanthines
  publication-title: J. Funct. Foods
  doi: 10.1016/j.jff.2018.02.001
  contributor:
    fullname: Carrageta
– ident: ref_36
  doi: 10.3390/nu12092499
– ident: ref_52
  doi: 10.3390/ijms21176181
– volume: 23
  start-page: 11
  year: 2009
  ident: ref_17
  article-title: Macrophage-Secreted Factors Promote a Profibrotic Phenotype in Human Preadipocytes
  publication-title: Mol. Endocrinol.
  doi: 10.1210/me.2008-0183
  contributor:
    fullname: Keophiphath
– volume: 84
  start-page: 135
  year: 2022
  ident: ref_16
  article-title: Adipose Tissue Fibrosis in Obesity: Etiology and Challenges
  publication-title: Annu. Rev. Physiol.
  doi: 10.1146/annurev-physiol-060721-092930
  contributor:
    fullname: Marcelin
– ident: ref_38
  doi: 10.3390/ijms24076621
– ident: ref_29
  doi: 10.3390/ijms222111832
– volume: 15
  start-page: 288
  year: 2019
  ident: ref_1
  article-title: Obesity: Global Epidemiology and Pathogenesis
  publication-title: Nat. Rev. Endocrinol.
  doi: 10.1038/s41574-019-0176-8
– ident: ref_31
  doi: 10.3390/molecules26144328
– ident: ref_50
  doi: 10.3390/nu14235099
– ident: ref_47
  doi: 10.3390/ijms24032310
– volume: 320
  start-page: C375
  year: 2021
  ident: ref_9
  article-title: Adipose Tissue Inflammation and Metabolic Dysfunction in Obesity
  publication-title: Am. J. Physiol.-Cell Physiol.
  doi: 10.1152/ajpcell.00379.2020
  contributor:
    fullname: Kawai
– volume: 35
  start-page: 108026
  year: 2021
  ident: ref_39
  article-title: From Obesity to Alzheimer’s Disease through Insulin Resistance
  publication-title: J. Diabetes Complicat.
  doi: 10.1016/j.jdiacomp.2021.108026
  contributor:
    fullname: Terzo
– volume: 14
  start-page: 2154
  year: 2006
  ident: ref_44
  article-title: Increase of Neuronal Histamine in Obese Rats Is Associated with Decreases in Body Weight and Plasma Triglycerides
  publication-title: Obesity
  doi: 10.1038/oby.2006.252
  contributor:
    fullname: Golozoubova
– volume: 10
  start-page: S4
  year: 2019
  ident: ref_2
  article-title: Humans against Obesity: Who Will Win?
  publication-title: Adv. Nutr.
  doi: 10.1093/advances/nmy055
  contributor:
    fullname: Caballero
– ident: ref_26
  doi: 10.3390/ijms23179867
– ident: ref_33
  doi: 10.3390/antiox11071313
– ident: ref_35
  doi: 10.3390/ijms231810465
– ident: ref_46
  doi: 10.3390/ijms23137011
– volume: 30
  start-page: 279
  year: 2023
  ident: ref_10
  article-title: Cell Death and Inflammation during Obesity: “Know My Methods, WAT(Son)”
  publication-title: Cell Death Differ.
  doi: 10.1038/s41418-022-01062-4
  contributor:
    fullname: Hildebrandt
– ident: ref_4
  doi: 10.1186/s12889-018-5392-y
– ident: ref_32
  doi: 10.3390/antiox8100422
– volume: 15
  start-page: 1631
  year: 2018
  ident: ref_51
  article-title: Melatonin and Vitamin D Orchestrate Adipose Derived Stem Cell Fate by Modulating Epigenetic Regulatory Genes
  publication-title: Int. J. Med. Sci.
  doi: 10.7150/ijms.27669
  contributor:
    fullname: Santaniello
– volume: 29
  start-page: 83
  year: 2018
  ident: ref_8
  article-title: Obesity and Inflammation
  publication-title: Eur. Cytokine Netw.
  doi: 10.1684/ecn.2018.0415
  contributor:
    fullname: Karczewski
– ident: ref_18
  doi: 10.3390/ijms24065672
– ident: ref_30
  doi: 10.3390/antiox11020363
– ident: ref_49
  doi: 10.3390/ijms23020956
– volume: 185
  start-page: 419
  year: 2022
  ident: ref_15
  article-title: Adipose-Tissue Plasticity in Health and Disease
  publication-title: Cell
  doi: 10.1016/j.cell.2021.12.016
  contributor:
    fullname: Sakers
– volume: 68
  start-page: 403
  year: 2018
  ident: ref_37
  article-title: Effects of Curcuminoids Plus Piperine on Glycemic, Hepatic and Inflammatory Biomarkers in Patients with Type 2 Diabetes Mellitus: A Randomized Double-Blind Placebo-Controlled Trial
  publication-title: Drug Res.
  doi: 10.1055/s-0044-101752
  contributor:
    fullname: Panahi
– volume: 11
  start-page: 621955
  year: 2021
  ident: ref_41
  article-title: Managing Obesity and Related Comorbidities: A Potential Pharmacological Target in the Adenosine System?
  publication-title: Front. Pharmacol.
  doi: 10.3389/fphar.2020.621955
  contributor:
    fullname: Fornai
– ident: ref_34
  doi: 10.3390/ijms24065419
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Snippet In the past 50 years, the global prevalence of obesity and overweight has tripled, reaching pandemic proportions and blatantly representing an urgent problem...
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SubjectTerms Adipocytes
Antioxidants
B cells
Bioavailability
Body fat
Cardiovascular disease
Chronic illnesses
Diabetes
Glucose
Humans
Hyaluronic acid
Hypoxia
Inflammation
Kinases
Lipids
Metabolism
n/a
Obesity
Obesity - epidemiology
Obesity - prevention & control
Overweight - epidemiology
Polyphenols
Prevalence
Prevention
Public Health
Resveratrol
Type 2 diabetes
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Title Multimodal Strategies to Fight Obesity: Research on Tailored Therapies Based on Natural and Synthetic Compounds for Prevention, Management and Treatment
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