Evaluating the Release of Different Commercial Orally Modified Niacin Formulations In Vitro

• Published in: Polymers Vol. 15; no. 14; p. 3046
• Main Authors: Chbib, Christiane, Rashid, Md Abdur, Shah, Sarthak M, Kazi, Mohsin, Uddin, Mohammad N
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.07.2023; MDPI
• Subjects: Acids; Bioavailability; Coatings; Comparative analysis; Dietary supplements; Dosage; Drug dosages; FDA approval; Good Manufacturing Practice; in vitro dissolution studies; Metabolic disorders; Metabolites; modified-release tablets; Niacin; niacin (nicotinic acid); Polymers; Product introduction; quantification; Stomach; Tablets; UV spectroscopy; Vitamin B; United States > US; quantification; niacin (nicotinic acid); UV spectroscopy; bioavailability; modified-release tablets; in vitro dissolution studies

To evaluate the release profile of different modified-release oral formulations of niacin, such as immediate-release (IR) powder and tablets, timed-release (TR) caplets, extended-release (ER) capsules, and controlled-release (CR) tablets, to assure their defined release pattern and correlate this re...