Water pumps

• Published in: The Journal of physiology Vol. 542; no. 1; pp. 53 - 60
• Main Authors: Loo, Donald D. F., Wright, Ernest M., Zeuthen, Thomas
• Format: Journal Article
• Language: English
• Published: Oxford, UK The Physiological Society 01.07.2002; Blackwell Publishing Ltd; Blackwell Science Inc
• Subjects: Animals; Biological Transport, Active - physiology; Epithelium - metabolism; Humans; Ion Channels - physiology; Kinetics; Osmosis; Topical Review; Water - metabolism

The transport of water across epithelia has remained an enigma ever since it was discovered over 100 years ago that water was transported across the isolated small intestine in the absence of osmotic and hydrostatic pressure gradients. While it is accepted that water transport is linked to solute tr...