The Role of Acrolein in Neurodegenerative Diseases and Its Protective Strategy

• Published in: Foods Vol. 11; no. 20; p. 3203
• Main Authors: Chang, Xinxin, Wang, Yudan, Zheng, Bing, Chen, Yi, Xie, Jianhua, Song, Yiming, Ding, Xiaomeng, Hu, Xiaoyi, Hu, Xiaobo, Yu, Qiang
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.10.2022; MDPI
• Subjects: Acrolein; Aldehydes; Alzheimer's disease; Contaminants; Degeneration; Fatty acids; Food; Food processing; Food science; Health aspects; inflammation; Ischemia; Lipid peroxidation; Lipids; Metabolism; Metabolites; Movement disorders; Multiple sclerosis; Natural products; Nervous system; Nervous system diseases; Neurodegenerative diseases; Optimization; Oxidative metabolism; Oxidative stress; Parkinson's disease; Pathogenesis; Pollutants; Pollution control; Polyamines; Regulatory mechanisms (biology); Review; Smoking; Stroke; Toxicity; Urine; China; United States > US; neurodegenerative diseases; inflammation; oxidative stress; acrolein

Neurodegenerative diseases are characterized by a massive loss of specific neurons, which can be fatal. Acrolein, an omnipresent environmental pollutant, is classified as a priority control contaminant by the EPA. Evidence suggests that acrolein is a highly active unsaturated aldehyde related to man...