Improved tumor-type informed compared to tumor-informed mutation tracking for ctDNA detection and microscopic residual disease assessment in epithelial ovarian cancer - Ben Sassi, Mehdi; Azais, Henri; Marcaillou, Charles; Guibert, Sylvain; Martin, Emmanuel; Alexandre, Jérôme; Benoit, Louise; de Reynies, Aurélien; Laude, Emilie; Duong, Cam; Medioni, Jacques; Borghese, Bruno; et al. (Journal of experimental & clinical cancer research, 2025)
Keywords: Adult; Aged; Biomarkers, Tumor - genetics; Cancer therapies; Carcinoma, Ovarian Epithelial - blood; Carcinoma, Ovarian Epithelial - diagnosis; Carcinoma, Ovarian Epithelial - genetics; Carcinoma, Ovarian Epithelial - pathology; Chemotherapy; Circulating Tumor DNA - blood; Circulating Tumor DNA - genetics; Design; DNA Methylation; Epigenetics; Exome Sequencing; Female; Health aspects; Humans; Methylation; Middle Aged; Mortality; Mutation; Neoplasm, Residual - genetics; Ovarian cancer; Ovarian Neoplasms - blood; Ovarian Neoplasms - genetics; Ovarian Neoplasms - pathology; Patients; Plasma; Surgery; Tumors; Whole genome sequencing