Biochemical and pharmacological effects of the direct thrombin inhibitor AR-H067637 - Deinum, Johanna; Mattsson, Christer; Inghardt, Tord; Elg, Margareta (Thrombosis and haemostasis, 2009)
Keywords: Amidines - pharmacokinetics; Amidines - pharmacology; Anticoagulants - pharmacology; Azetidines - pharmacokinetics; Azetidines - pharmacology; Binding, Competitive; Blood Coagulation - drug effects; Blood Coagulation Factors - metabolism; Blood Platelets - enzymology; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Humans; Inhibitory Concentration 50; Male; Platelet Activation - drug effects; Protein Binding; Thrombin - antagonists & inhibitors; Whole Blood Coagulation Time