Meta-Analysis of Cytokines and Chemokines in Suicidality: Distinguishing Suicidal Versus Nonsuicidal Patients

• Published in: Biological psychiatry (1969) Vol. 78; no. 1; pp. 28 - 37
• Main Authors: Black, Carmen, Miller, Brian J.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2015
• Subjects: Adolescent; Adult; Brain - metabolism; Chemokines; Chemokines - blood; Chemokines - cerebrospinal fluid; Cytokines; Cytokines - blood; Cytokines - cerebrospinal fluid; Depression; Female; Humans; Inflammation; Inflammation - blood; Inflammation - cerebrospinal fluid; Interleukin-1beta - blood; Interleukin-1beta - cerebrospinal fluid; Interleukin-8 - blood; Interleukin-8 - cerebrospinal fluid; Male; Mental Disorders - blood; Mental Disorders - cerebrospinal fluid; Mental Disorders - complications; Meta-analysis; Middle Aged; Psychiatric/Mental Health; Receptors, Interleukin-6 - analysis; Receptors, Interleukin-6 - blood; Suicide; Depression; Inflammation; Cytokines; Suicide; Chemokines; Meta-analysis

Major psychiatric disorders are associated with inflammation. Aberrant cytokine and chemokine levels have been associated with psychiatric disorders and suicidal behavior. We performed a meta-analysis of cytokine and chemokine levels in patients with versus without suicidality and patients with suic...