Ionic liquids and cyclodextrin inclusion complexes: limitation of the affinity capillary electrophoresis technique

• Published in: Analytical and bioanalytical chemistry Vol. 408; no. 28; pp. 8211 - 8220
• Main Authors: Mofaddel, Nadine, Fourmentin, Sophie, Guillen, Fréderic, Landy, David, Gouhier, Géraldine
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.11.2016; Springer; Springer Nature B.V; Springer Verlag
• Subjects: Affinity; Analytical Chemistry; Biochemistry; Calorimetry; Capillary electrophoresis; Characterization and Evaluation of Materials; Chemical properties; Chemical Sciences; Chemistry; Chemistry and Materials Science; Chromatography; Cyclodextrins; Electrophoresis; Food Science; Holes; Inclusion complexes; Ionic liquids; Laboratory Medicine; Mathematical analysis; Methods; Monitoring/Environmental Analysis; NMR; Nuclear magnetic resonance; Research Paper; Titration calorimetry; France; Affinity capillary electrophoresis; Cyclodextrin; Isothermal titration calorimetry; Binding constants; Ionic liquid
• ISSN: 1618-2642; 1618-2650
• DOI: 10.1007/s00216-016-9931-z

The state of the art of inclusion complex formation between cyclodextrins and ionic liquids is reported. Mechanisms, stoichiometries, and binding constants are summarized and classified by anion. We investigated the supramolecular interactions between the β-cyclodextrin cavity and six ionic liquids based on 1-dodecyl-3-methylimidazolium by affinity capillary electrophoresis and compared the results with those obtained by isothermal titration calorimetry. We show that the presence of basic or acidic buffers leads to a metathesis reaction, underlining the limitation of the affinity capillary electrophoresis technique.