Individual-level cortical morphological network analysis in idiopathic normal pressure hydrocephalus: diagnostic and prognostic insights

• Published in: Fluids and barriers of the CNS Vol. 22; no. 1; pp. 43 - 20
• Main Authors: Yang, Yifeng, Yan, Meijing, Sun, Lianxi, Liu, Xiao, Fang, Xuhao, Li, Shihong, Lin, Guangwu
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 06.05.2025; BioMed Central; BMC
• Subjects: Advertising executives; Aged; Aged, 80 and over; Alzheimer Disease - diagnostic imaging; Alzheimer Disease - pathology; Alzheimer's disease; Atrophy; Brain architecture; Cerebral Cortex - diagnostic imaging; Cerebral Cortex - pathology; Cerebrospinal fluid; Cognitive ability; Diagnosis; Female; Gait; Hospitals; Humans; Hydrocephalus; Hydrocephalus, Normal Pressure - diagnosis; Hydrocephalus, Normal Pressure - diagnostic imaging; Hydrocephalus, Normal Pressure - pathology; Hydrocephalus, Normal Pressure - surgery; Idiopathic normal pressure hydrocephalus; Magnetic Resonance Imaging; Male; Middle Aged; Morphological similarity networks; Morphology; Morphometric inverse divergence network; Nerve Net - diagnostic imaging; Nerve Net - pathology; Nervous system diseases; Neurodegenerative diseases; Pathology; Patients; Prediction of shunt efficacy; Prognosis; Support Vector Machine; Surgery; Taiwan; Morphological similarity networks; Diagnosis; Morphometric inverse divergence network; Prediction of shunt efficacy; Idiopathic normal pressure hydrocephalus

Idiopathic normal-pressure hydrocephalus (iNPH) is a neurodegenerative disorder characterized by treatable cognitive impairment, remains poorly understood in terms of its underlying pathological mechanisms. Cortical morphological similarity network, which quantify synchronized morphological changes...