Deciphering cholangiocarcinoma heterogeneity and specific progenitor cell niche of extrahepatic cholangiocarcinoma at single-cell resolution - Liu, Chunliang; Wang, Xiang; Liu, Erdong; Zong, Yali; Yu, Wenlong; Jiang, Youhai; Chen, Jianan; Gu, Mingye; Meng, Zhengyuan; Li, Jingfeng; Liu, Yang; Zhang, Yongjie; et al. (Journal of hematology and oncology, 2025)
Keywords: Analysis; Animal models; Animals; B cells; Bile Duct Neoplasms - genetics; Bile Duct Neoplasms - pathology; Bile ducts; Biological response modifiers; Cancer; Cell cycle; Cholangiocarcinoma; Cholangiocarcinoma - genetics; Cholangiocarcinoma - pathology; Clinical trials; DNA microarrays; Drug resistance; Epithelial cells; Genes; Genomes; Genomics; Humans; Immunotherapy; Inflammation; Interferon; Malignancy; Medical prognosis; Mice; Microenvironments; Neoplastic Stem Cells - metabolism; Neoplastic Stem Cells - pathology; Oncology; Organoids; Patients; Precision medicine; Progenitor cells; RNA; RNA sequencing; Senescence; Single-Cell Analysis - methods; Stem Cell Niche; Stem cells; Therapeutic targets; Transcriptomics; Tumor Microenvironment; Tumorigenesis