Escherichia coli‐associated follicular cystitis in dogs: Clinical and pathologic characterization

Background Follicular cystitis is an uncommon inflammatory change in the urinary bladder wall characterized by the formation of tertiary lymphoid structures (TLSs) in the submucosa. Objectives To characterize clinical and pathologic features of follicular cystitis in dogs and to explore in situ dist...

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Published inJournal of veterinary internal medicine Vol. 37; no. 3; pp. 1059 - 1066
Main Authors Viitanen, Sanna J., Tuomisto, Laura, Salonen, Nina, Eskola, Katariina, Kegler, Kristel
Format Journal Article
LanguageEnglish
Published Hoboken, USA John Wiley & Sons, Inc 01.05.2023
Wiley
Subjects
Animal euthanasia
Animals
Biochemistry
Biopsy
Bladder
canine
cystitis
Cystitis - pathology
Cystitis - veterinary
Dendritic cells
descriptive studies
Dog Diseases - diagnosis
Dogs
E coli
Escherichia coli
Escherichia coli Infections - complications
Escherichia coli Infections - veterinary
Female
females
Hematology
Histopathology
Hybridization
in situ hybridization
inflammation
Laboratories
mucosa
Retrospective Studies
SMALL ANIMAL
Teaching hospitals
Ultrasonic imaging
urinary
Urinary Bladder - pathology
Urinary tract diseases
Urinary tract infections
Urinary Tract Infections - veterinary
Urine
Urogenital system
Veterinary medicine
California
United Kingdom > UK
United States > US
Germany
Finland
histopathology
canine
urinary
in situ hybridization
Online AccessGet full text

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Abstract Background Follicular cystitis is an uncommon inflammatory change in the urinary bladder wall characterized by the formation of tertiary lymphoid structures (TLSs) in the submucosa. Objectives To characterize clinical and pathologic features of follicular cystitis in dogs and to explore in situ distribution and possible role of Escherichia coli as an associated cause. Animals Eight dogs diagnosed with follicular cystitis and 2 control dogs. Methods Retrospective descriptive study. Dogs diagnosed with follicular cystitis (macroscopic follicular lesions in the urinary bladder mucosa and histopathologic detection of TLSs in bladder wall biopsies) were identified from medical records. Paraffin embedded bladder wall biopsies were subject to in situ hybridization for E. coli 16SrRNA identification. Results Follicular cystitis was diagnosed in large breed (median weight 24.9 kg, interquartile range [IQR] 18.8‐35.4 kg) female dogs with a history of chronic recurrent urinary tract infections (UTIs; median duration of clinical signs 7 months, IQR 3‐17 months; median number of previous UTIs 5, IQR 4‐6). Positive E. coli 16SrRNA signal was detected within developing, immature and mature TLSs in 7/8 dogs, through submucosal stroma in 8/8 dogs and within the urothelium in 3/8 dogs. Conclusions and Clinical Importance Chronic inflammation associated with an intramural E. coli infection in the urinary bladder wall represents a possible triggering factor for the development of follicular cystitis.
AbstractList Background Follicular cystitis is an uncommon inflammatory change in the urinary bladder wall characterized by the formation of tertiary lymphoid structures (TLSs) in the submucosa. Objectives To characterize clinical and pathologic features of follicular cystitis in dogs and to explore in situ distribution and possible role of Escherichia coli as an associated cause. Animals Eight dogs diagnosed with follicular cystitis and 2 control dogs. Methods Retrospective descriptive study. Dogs diagnosed with follicular cystitis (macroscopic follicular lesions in the urinary bladder mucosa and histopathologic detection of TLSs in bladder wall biopsies) were identified from medical records. Paraffin embedded bladder wall biopsies were subject to in situ hybridization for E. coli 16SrRNA identification. Results Follicular cystitis was diagnosed in large breed (median weight 24.9 kg, interquartile range [IQR] 18.8‐35.4 kg) female dogs with a history of chronic recurrent urinary tract infections (UTIs; median duration of clinical signs 7 months, IQR 3‐17 months; median number of previous UTIs 5, IQR 4‐6). Positive E. coli 16SrRNA signal was detected within developing, immature and mature TLSs in 7/8 dogs, through submucosal stroma in 8/8 dogs and within the urothelium in 3/8 dogs. Conclusions and Clinical Importance Chronic inflammation associated with an intramural E. coli infection in the urinary bladder wall represents a possible triggering factor for the development of follicular cystitis.
Follicular cystitis is an uncommon inflammatory change in the urinary bladder wall characterized by the formation of tertiary lymphoid structures (TLSs) in the submucosa.BACKGROUNDFollicular cystitis is an uncommon inflammatory change in the urinary bladder wall characterized by the formation of tertiary lymphoid structures (TLSs) in the submucosa.To characterize clinical and pathologic features of follicular cystitis in dogs and to explore in situ distribution and possible role of Escherichia coli as an associated cause.OBJECTIVESTo characterize clinical and pathologic features of follicular cystitis in dogs and to explore in situ distribution and possible role of Escherichia coli as an associated cause.Eight dogs diagnosed with follicular cystitis and 2 control dogs.ANIMALSEight dogs diagnosed with follicular cystitis and 2 control dogs.Retrospective descriptive study. Dogs diagnosed with follicular cystitis (macroscopic follicular lesions in the urinary bladder mucosa and histopathologic detection of TLSs in bladder wall biopsies) were identified from medical records. Paraffin embedded bladder wall biopsies were subject to in situ hybridization for E. coli 16SrRNA identification.METHODSRetrospective descriptive study. Dogs diagnosed with follicular cystitis (macroscopic follicular lesions in the urinary bladder mucosa and histopathologic detection of TLSs in bladder wall biopsies) were identified from medical records. Paraffin embedded bladder wall biopsies were subject to in situ hybridization for E. coli 16SrRNA identification.Follicular cystitis was diagnosed in large breed (median weight 24.9 kg, interquartile range [IQR] 18.8-35.4 kg) female dogs with a history of chronic recurrent urinary tract infections (UTIs; median duration of clinical signs 7 months, IQR 3-17 months; median number of previous UTIs 5, IQR 4-6). Positive E. coli 16SrRNA signal was detected within developing, immature and mature TLSs in 7/8 dogs, through submucosal stroma in 8/8 dogs and within the urothelium in 3/8 dogs.RESULTSFollicular cystitis was diagnosed in large breed (median weight 24.9 kg, interquartile range [IQR] 18.8-35.4 kg) female dogs with a history of chronic recurrent urinary tract infections (UTIs; median duration of clinical signs 7 months, IQR 3-17 months; median number of previous UTIs 5, IQR 4-6). Positive E. coli 16SrRNA signal was detected within developing, immature and mature TLSs in 7/8 dogs, through submucosal stroma in 8/8 dogs and within the urothelium in 3/8 dogs.Chronic inflammation associated with an intramural E. coli infection in the urinary bladder wall represents a possible triggering factor for the development of follicular cystitis.CONCLUSIONS AND CLINICAL IMPORTANCEChronic inflammation associated with an intramural E. coli infection in the urinary bladder wall represents a possible triggering factor for the development of follicular cystitis.
BACKGROUND: Follicular cystitis is an uncommon inflammatory change in the urinary bladder wall characterized by the formation of tertiary lymphoid structures (TLSs) in the submucosa. OBJECTIVES: To characterize clinical and pathologic features of follicular cystitis in dogs and to explore in situ distribution and possible role of Escherichia coli as an associated cause. ANIMALS: Eight dogs diagnosed with follicular cystitis and 2 control dogs. METHODS: Retrospective descriptive study. Dogs diagnosed with follicular cystitis (macroscopic follicular lesions in the urinary bladder mucosa and histopathologic detection of TLSs in bladder wall biopsies) were identified from medical records. Paraffin embedded bladder wall biopsies were subject to in situ hybridization for E. coli 16SrRNA identification. RESULTS: Follicular cystitis was diagnosed in large breed (median weight 24.9 kg, interquartile range [IQR] 18.8‐35.4 kg) female dogs with a history of chronic recurrent urinary tract infections (UTIs; median duration of clinical signs 7 months, IQR 3‐17 months; median number of previous UTIs 5, IQR 4‐6). Positive E. coli 16SrRNA signal was detected within developing, immature and mature TLSs in 7/8 dogs, through submucosal stroma in 8/8 dogs and within the urothelium in 3/8 dogs. CONCLUSIONS AND CLINICAL IMPORTANCE: Chronic inflammation associated with an intramural E. coli infection in the urinary bladder wall represents a possible triggering factor for the development of follicular cystitis.
Follicular cystitis is an uncommon inflammatory change in the urinary bladder wall characterized by the formation of tertiary lymphoid structures (TLSs) in the submucosa. To characterize clinical and pathologic features of follicular cystitis in dogs and to explore in situ distribution and possible role of Escherichia coli as an associated cause. Eight dogs diagnosed with follicular cystitis and 2 control dogs. Retrospective descriptive study. Dogs diagnosed with follicular cystitis (macroscopic follicular lesions in the urinary bladder mucosa and histopathologic detection of TLSs in bladder wall biopsies) were identified from medical records. Paraffin embedded bladder wall biopsies were subject to in situ hybridization for E. coli 16SrRNA identification. Follicular cystitis was diagnosed in large breed (median weight 24.9 kg, interquartile range [IQR] 18.8-35.4 kg) female dogs with a history of chronic recurrent urinary tract infections (UTIs; median duration of clinical signs 7 months, IQR 3-17 months; median number of previous UTIs 5, IQR 4-6). Positive E. coli 16SrRNA signal was detected within developing, immature and mature TLSs in 7/8 dogs, through submucosal stroma in 8/8 dogs and within the urothelium in 3/8 dogs. Chronic inflammation associated with an intramural E. coli infection in the urinary bladder wall represents a possible triggering factor for the development of follicular cystitis.
Abstract Background Follicular cystitis is an uncommon inflammatory change in the urinary bladder wall characterized by the formation of tertiary lymphoid structures (TLSs) in the submucosa. Objectives To characterize clinical and pathologic features of follicular cystitis in dogs and to explore in situ distribution and possible role of Escherichia coli as an associated cause. Animals Eight dogs diagnosed with follicular cystitis and 2 control dogs. Methods Retrospective descriptive study. Dogs diagnosed with follicular cystitis (macroscopic follicular lesions in the urinary bladder mucosa and histopathologic detection of TLSs in bladder wall biopsies) were identified from medical records. Paraffin embedded bladder wall biopsies were subject to in situ hybridization for E. coli 16SrRNA identification. Results Follicular cystitis was diagnosed in large breed (median weight 24.9 kg, interquartile range [IQR] 18.8‐35.4 kg) female dogs with a history of chronic recurrent urinary tract infections (UTIs; median duration of clinical signs 7 months, IQR 3‐17 months; median number of previous UTIs 5, IQR 4‐6). Positive E. coli 16SrRNA signal was detected within developing, immature and mature TLSs in 7/8 dogs, through submucosal stroma in 8/8 dogs and within the urothelium in 3/8 dogs. Conclusions and Clinical Importance Chronic inflammation associated with an intramural E. coli infection in the urinary bladder wall represents a possible triggering factor for the development of follicular cystitis.
BackgroundFollicular cystitis is an uncommon inflammatory change in the urinary bladder wall characterized by the formation of tertiary lymphoid structures (TLSs) in the submucosa.ObjectivesTo characterize clinical and pathologic features of follicular cystitis in dogs and to explore in situ distribution and possible role of Escherichia coli as an associated cause.AnimalsEight dogs diagnosed with follicular cystitis and 2 control dogs.MethodsRetrospective descriptive study. Dogs diagnosed with follicular cystitis (macroscopic follicular lesions in the urinary bladder mucosa and histopathologic detection of TLSs in bladder wall biopsies) were identified from medical records. Paraffin embedded bladder wall biopsies were subject to in situ hybridization for E. coli 16SrRNA identification.ResultsFollicular cystitis was diagnosed in large breed (median weight 24.9 kg, interquartile range [IQR] 18.8-35.4 kg) female dogs with a history of chronic recurrent urinary tract infections (UTIs; median duration of clinical signs 7 months, IQR 3-17 months; median number of previous UTIs 5, IQR 4-6). Positive E. coli 16SrRNA signal was detected within developing, immature and mature TLSs in 7/8 dogs, through submucosal stroma in 8/8 dogs and within the urothelium in 3/8 dogs.Conclusions and Clinical ImportanceChronic inflammation associated with an intramural E. coli infection in the urinary bladder wall represents a possible triggering factor for the development of follicular cystitis.
Author Kegler, Kristel
Viitanen, Sanna J.
Eskola, Katariina
Tuomisto, Laura
Salonen, Nina
AuthorAffiliation 2 Department of Veterinary Biosciences, Pathology and Parasitology Unit, Faculty of Veterinary Medicine University of Helsinki Helsinki Finland
1 Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine University of Helsinki Helsinki Finland
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– name: 2 Department of Veterinary Biosciences, Pathology and Parasitology Unit, Faculty of Veterinary Medicine University of Helsinki Helsinki Finland
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Cites_doi 10.1016/j.tvjl.2010.11.013
10.1111/j.1939-1676.2010.0562.x
10.1016/j.eucr.2017.06.008
10.1016/S0002-9343(02)01054-9
10.1038/s41385-020-0290-x
10.1128/AAC.00014-10
10.1038/nri1786
10.1016/j.juro.2011.07.114
10.1136/vetreccr-2014-000106
10.1128/9781555816728
10.1016/j.jmb.2019.04.008
10.3389/fmicb.2017.01566
10.1016/S0022-5347(17)39950-0
10.1073/pnas.0602136103
10.1177/1040638717729395
10.1016/S0022-5347(17)70783-5
10.1016/j.tvjl.2019.02.008
10.1007/s11250-011-9978-y
10.1016/j.imbio.2011.05.011
10.1016/S0022-5347(17)61817-2
10.1016/j.urology.2015.04.002
10.4049/jimmunol.2000873
10.1111/jvim.15728
10.1046/j.1462-5822.2002.00193.x
10.1111/j.1365-2362.2008.01986.x
10.1038/s41598-017-02516-3
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Issue 3
Keywords histopathology
canine
urinary
in situ hybridization
Language English
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References 2017; 7
2010; 54
1970; 104
2011; 216
2011
2002; 113
2017; 24
2008; 38
2021; 206
2019; 247
2006; 6
2002; 4
2020; 13
2020; 34
2011; 190
2020; 55
1942; 47
1990; 143
2014; 2
2010; 24
1940; 29
2017; 15
2017; 14
2015; 86
2020; 9
2018; 30
2014
2013
2012; 44
2019; 431
2006; 103
2011; 186
Ediz C (e_1_2_11_15_1) 2017; 24
e_1_2_11_32_1
e_1_2_11_31_1
e_1_2_11_30_1
Gulinac M (e_1_2_11_10_1) 2020; 9
e_1_2_11_14_1
e_1_2_11_13_1
e_1_2_11_12_1
e_1_2_11_11_1
e_1_2_11_33_1
e_1_2_11_7_1
Clinical and Laboratory Standards Institute (CLSI) (e_1_2_11_21_1) 2014
e_1_2_11_29_1
e_1_2_11_6_1
e_1_2_11_28_1
e_1_2_11_27_1
e_1_2_11_4_1
Clinical and Laboratory Standards Institute (CLSI) (e_1_2_11_20_1) 2013
e_1_2_11_26_1
e_1_2_11_3_1
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References_xml – year: 2011
– volume: 29
  start-page: 511
  year: 1940
  end-page: 516
  article-title: Cystitis follicularis in a dog
  publication-title: Arch Pathol
– volume: 9
  start-page: 64
  issue: 5
  year: 2020
  article-title: Current concept for tertiary lymphoid structures in urothelial carcinoma of the bladder: a literature review and our experience
  publication-title: Am J Clin Exp Immunol
– volume: 47
  start-page: 168
  issue: 2
  year: 1942
  end-page: 170
  article-title: Cystitis follicularis
  publication-title: J Urol
– volume: 38
  start-page: 2
  issue: SUPPL 2
  year: 2008
  end-page: 11
  article-title: Mechanisms and consequences of bladder cell invasion by uropathogenic
  publication-title: Eur J Clin Invest
– volume: 216
  start-page: 1164
  issue: 11
  year: 2011
  end-page: 1171
  article-title: Intramacrophage survival of uropathogenic : differences between diverse clinical isolates and between mouse and human macrophages
  publication-title: Immunobiology
– volume: 4
  start-page: 257
  issue: 5
  year: 2002
  end-page: 271
  article-title: Adhesion and entry of uropathogenic
  publication-title: Cell Microbiol
– volume: 54
  start-page: 1855
  issue: 5
  year: 2010
  end-page: 1863
  article-title: Persistence of uropathogenic in the face of multiple antibiotics
  publication-title: Antimicrob Agents Chemother
– volume: 6
  start-page: 205
  issue: 3
  year: 2006
  end-page: 217
  article-title: Lymphoid neogenesis in chronic inflammatory diseases
  publication-title: Nat Rev Immunol
– volume: 30
  start-page: 64
  issue: 1
  year: 2018
  end-page: 70
  article-title: Phylogroup and virulence gene association with clinical characteristics of urinary tract infections from dogs and cats
  publication-title: J Vet Diagn Invest
– volume: 2
  issue: 1
  year: 2014
  article-title: Follicular cystitis in a dog
  publication-title: Vet Rec Case Rep
– volume: 186
  start-page: 2359
  issue: 6
  year: 2011
  end-page: 2364
  article-title: B cell infiltration and lymphonodular hyperplasia in bladder submucosa of patients with persistent bacteriuria and recurrent urinary tract infections
  publication-title: J Urol
– volume: 24
  start-page: 117
  issue: 1
  year: 2017
  end-page: 120
  article-title: Follicular cystitis: a review of the literature with several cases/Folikuler sistit: cesitli olgular esliginde literatur derlemesi
  publication-title: J Turgut Ozal Med Cent
– year: 2014
– volume: 113
  start-page: 5
  issue: 1
  year: 2002
  end-page: 13
  article-title: Epidemiology of urinary tract infections: incidence, morbidity, and economic costs
  publication-title: Am J Med
– volume: 103
  start-page: 14170
  issue: 38
  year: 2006
  end-page: 14175
  article-title: Mechanisms of uropathogenic persistence and eradication from the urinary tract
  publication-title: Proc Natl Acad Sci U S A
– volume: 14
  start-page: 38
  year: 2017
  end-page: 41
  article-title: von Brunn's nests and follicular cystitis following intradetrusor onabotulinumtoxinA injections for overactive bladder
  publication-title: Urol Case Rep
– volume: 55
  start-page: 49
  issue: 2
  year: 2020
  end-page: 54
  article-title: Isolation and prevalence of uropathogenic in different breed, sex and age of dogs
  publication-title: Rev Vet Clin
– volume: 7
  start-page: 5752
  year: 2017
  article-title: Comparison of DNA‐, PMA‐, and RNA‐based 16S rRNA Illumina sequencing for detection of live bacteria in water
  publication-title: Sci Rep
– volume: 44
  start-page: 855
  issue: 4
  year: 2012
  end-page: 861
  article-title: Pathological study of non‐neoplastic urinary bladder lesions in cattle and buffaloes: a preliminary report
  publication-title: Tropl Anim Health Prod
– volume: 431
  start-page: 4368
  issue: 21
  year: 2019
  end-page: 4379
  article-title: Direct detection of tissue‐resident bacteria and chronic inflammation in the bladder wall of postmenopausal women with recurrent urinary tract infection
  publication-title: J Mol Biol
– volume: 13
  start-page: 908
  issue: 6
  year: 2020
  end-page: 918
  article-title: Single cell and tissue‐transcriptomic analysis of murine bladders reveals age‐ and TNFα‐dependent but microbiota‐independent tertiary lymphoid tissue formation
  publication-title: Mucosal Immunol
– volume: 15
  start-page: 1566
  issue: 8
  year: 2017
  article-title: UroPathogenic (UPEC) infections: virulence factors, bladder responses, antibiotic, and non‐antibiotic antimicrobial strategies
  publication-title: Front Microbiol
– volume: 143
  start-page: 330
  issue: 2
  year: 1990
  end-page: 332
  article-title: Follicular cystitis in girls with untreated asymptomatic or covert bacteriuria
  publication-title: J Urol
– volume: 24
  start-page: 1055
  issue: 5
  year: 2010
  end-page: 1062
  article-title: Congenital ureteral ectopia in continent and incontinent‐related Entlebucher mountain dogs: 13 cases (2006–2009)
  publication-title: J Vet Intern Med
– volume: 190
  start-page: 22
  issue: 1
  year: 2011
  end-page: 27
  article-title: Canine bacterial urinary tract infections: new developments in old pathogens
  publication-title: Vet J
– volume: 104
  start-page: 709
  issue: 5
  year: 1970
  end-page: 714
  article-title: On the nature of cystitis follicularis
  publication-title: J Urol
– volume: 34
  start-page: 790
  issue: 2
  year: 2020
  end-page: 796
  article-title: Transurethral cystoscopy in dogs with recurrent urinary tract infections: retrospective study (2011‐2018)
  publication-title: J Vet Intern Med
– volume: 86
  start-page: 425
  issue: 3
  year: 2015
  end-page: 431
  article-title: Intracellular bacterial communities: a potential etiology for chronic lower urinary tract symptoms
  publication-title: Urology
– volume: 247
  start-page: 8
  year: 2019
  end-page: 25
  article-title: International Society for Companion Animal Infectious Diseases (ISCAID) guidelines for the diagnosis and management of bacterial urinary tract infections in dogs and cats
  publication-title: Vet J
– volume: 206
  start-page: 273
  issue: 2
  year: 2021
  end-page: 281
  article-title: Tertiary lymphoid structures: diversity in their development, composition, and role
  publication-title: J Immunol
– year: 2013
– volume-title: Performance Standards for Antimicrobial Disk and Dilution Susceptibility Tests for Bacteria Isolated from Animals, CLSI Supplement VET01‐A4
  year: 2013
  ident: e_1_2_11_20_1
– ident: e_1_2_11_12_1
  doi: 10.1016/j.tvjl.2010.11.013
– ident: e_1_2_11_17_1
  doi: 10.1111/j.1939-1676.2010.0562.x
– ident: e_1_2_11_9_1
  doi: 10.1016/j.eucr.2017.06.008
– ident: e_1_2_11_11_1
  doi: 10.1016/S0002-9343(02)01054-9
– ident: e_1_2_11_24_1
  doi: 10.1038/s41385-020-0290-x
– ident: e_1_2_11_32_1
  doi: 10.1128/AAC.00014-10
– ident: e_1_2_11_23_1
  doi: 10.1038/nri1786
– ident: e_1_2_11_8_1
  doi: 10.1016/j.juro.2011.07.114
– volume: 55
  start-page: 49
  issue: 2
  year: 2020
  ident: e_1_2_11_22_1
  article-title: Isolation and prevalence of uropathogenic E. coli in different breed, sex and age of dogs
  publication-title: Rev Vet Clin
– ident: e_1_2_11_16_1
  doi: 10.1136/vetreccr-2014-000106
– ident: e_1_2_11_19_1
  doi: 10.1128/9781555816728
– ident: e_1_2_11_28_1
  doi: 10.1016/j.jmb.2019.04.008
– ident: e_1_2_11_14_1
  doi: 10.3389/fmicb.2017.01566
– ident: e_1_2_11_7_1
  doi: 10.1016/S0022-5347(17)39950-0
– volume-title: Performance Standards for Antimicrobial Susceptibility Testing, CLSI Supplement M100‐S2
  year: 2014
  ident: e_1_2_11_21_1
– ident: e_1_2_11_33_1
  doi: 10.1073/pnas.0602136103
– ident: e_1_2_11_13_1
  doi: 10.1177/1040638717729395
– ident: e_1_2_11_3_1
  doi: 10.1016/S0022-5347(17)70783-5
– ident: e_1_2_11_30_1
  doi: 10.1016/j.tvjl.2019.02.008
– ident: e_1_2_11_6_1
  doi: 10.1007/s11250-011-9978-y
– ident: e_1_2_11_27_1
  doi: 10.1016/j.imbio.2011.05.011
– ident: e_1_2_11_2_1
  doi: 10.1016/S0022-5347(17)61817-2
– ident: e_1_2_11_29_1
  doi: 10.1016/j.urology.2015.04.002
– ident: e_1_2_11_4_1
  doi: 10.4049/jimmunol.2000873
– volume: 9
  start-page: 64
  issue: 5
  year: 2020
  ident: e_1_2_11_10_1
  article-title: Current concept for tertiary lymphoid structures in urothelial carcinoma of the bladder: a literature review and our experience
  publication-title: Am J Clin Exp Immunol
– volume: 24
  start-page: 117
  issue: 1
  year: 2017
  ident: e_1_2_11_15_1
  article-title: Follicular cystitis: a review of the literature with several cases/Folikuler sistit: cesitli olgular esliginde literatur derlemesi
  publication-title: J Turgut Ozal Med Cent
– ident: e_1_2_11_18_1
  doi: 10.1111/jvim.15728
– ident: e_1_2_11_25_1
  doi: 10.1046/j.1462-5822.2002.00193.x
– ident: e_1_2_11_26_1
  doi: 10.1111/j.1365-2362.2008.01986.x
– ident: e_1_2_11_31_1
  doi: 10.1038/s41598-017-02516-3
– volume: 29
  start-page: 511
  year: 1940
  ident: e_1_2_11_5_1
  article-title: Cystitis follicularis in a dog
  publication-title: Arch Pathol
– reference: 37497786 - J Vet Intern Med. 2023 Jul 27;:
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Snippet Background Follicular cystitis is an uncommon inflammatory change in the urinary bladder wall characterized by the formation of tertiary lymphoid structures...
Follicular cystitis is an uncommon inflammatory change in the urinary bladder wall characterized by the formation of tertiary lymphoid structures (TLSs) in the...
BackgroundFollicular cystitis is an uncommon inflammatory change in the urinary bladder wall characterized by the formation of tertiary lymphoid structures...
BACKGROUND: Follicular cystitis is an uncommon inflammatory change in the urinary bladder wall characterized by the formation of tertiary lymphoid structures...
Abstract Background Follicular cystitis is an uncommon inflammatory change in the urinary bladder wall characterized by the formation of tertiary lymphoid...
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StartPage 1059
SubjectTerms Animal euthanasia
Animals
Biochemistry
Biopsy
Bladder
canine
cystitis
Cystitis - pathology
Cystitis - veterinary
Dendritic cells
descriptive studies
Dog Diseases - diagnosis
Dogs
E coli
Escherichia coli
Escherichia coli Infections - complications
Escherichia coli Infections - veterinary
Female
females
Hematology
Histopathology
Hybridization
in situ hybridization
inflammation
Laboratories
mucosa
Retrospective Studies
SMALL ANIMAL
Teaching hospitals
Ultrasonic imaging
urinary
Urinary Bladder - pathology
Urinary tract diseases
Urinary tract infections
Urinary Tract Infections - veterinary
Urine
Urogenital system
Veterinary medicine
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Title Escherichia coli‐associated follicular cystitis in dogs: Clinical and pathologic characterization
URI https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fjvim.16719
https://www.ncbi.nlm.nih.gov/pubmed/37154220
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https://doaj.org/article/f992c45277a94dbf8334a8fe6a43e1c9
Volume 37
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