Recovery from cortical blindness with mepivacaïne

• Published in: Annals of clinical and translational neurology Vol. 6; no. 8; pp. 1541 - 1545
• Main Authors: Cohen, Laurent, Ponchel, Amélie, Kas, Aurélie, Ströer, Sébastian, Del Cul, Antoine, Guérineau de Lamérie, Guillaume, El Hachem, Randa, Crépin, Piirika, Morin, Alexandre
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.08.2019; Wiley; John Wiley and Sons Inc
• Subjects: Anesthesia; Blindness, Cortical - drug therapy; Blindness, Cortical - etiology; Blindness, Cortical - physiopathology; Brain; Brain - pathology; Brief Communication; Brief Communications; Cerebral Cortex - pathology; Cognition & reasoning; Humans; Life Sciences; Magnetic Resonance Imaging; Male; Medication; Mepivacaine - therapeutic use; Metabolism; Middle Aged; Neurobiology; Neurons and Cognition; Paroxetine - therapeutic use; Pharmaceutical sciences; Stroke; Stroke - complications; Stroke - physiopathology

We report the case of a patient suffering from cortical blindness following bilateral occipital stroke, who recovered normal vision in his right visual field following injection of the local anesthetic mepivacaïne. The effect was transient but reproducible, allowing the patient to lead a normal life...