Stored erythrocytes have less capacity than normal erythrocytes to support primary haemostasis

• Published in: Thrombosis and haemostasis Vol. 101; no. 4; p. 720
• Main Authors: Reinhart, Walter H, Zehnder, Linda, Schulzki, Thomas
• Format: Journal Article
• Language: English
• Published: Germany 01.04.2009
• Subjects: Adult; Blood Coagulation Tests; Blood Donors; Blood Specimen Collection; Blood Viscosity; Erythrocyte Count; Erythrocyte Deformability; Erythrocyte Transfusion - adverse effects; Erythrocytes - pathology; Female; Hematocrit; Hemorrhage - blood; Hemorrhage - etiology; Hemostasis; Humans; Male; Middle Aged; Platelet Adhesiveness; Platelet Aggregation; Platelet Function Tests; Refrigeration; Time Factors; Young Adult

Primary haemostasis is mediated by platelet aggregation. Red blood cells (RBCs) are involved in this process. We hypothesised that stored RBCs could have less capacity to support primary haemostasis. This was tested with RBC units from 17 healthy volunteers stored for 45 days. Fresh citrated blood w...