Global Metabolomics of the Placenta Reveals Distinct Metabolic Profiles between Maternal and Fetal Placental Tissues Following Delivery in Non-Labored Women

• Published in: Metabolites Vol. 8; no. 1; p. 10
• Main Authors: Walejko, Jacquelyn M, Chelliah, Anushka, Keller-Wood, Maureen, Gregg, Anthony, Edison, Arthur S
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 23.01.2018; MDPI
• Subjects: 1H-NMR; Cesarean section; Fetuses; human; Metabolism; Metabolites; Metabolomics; NMR; Nuclear magnetic resonance; Placenta; pregnancy; placenta; 1H-NMR; metabolomics; human; pregnancy

We evaluated the metabolic alterations in maternal and fetal placental tissues from non-labored women undergoing cesarean section using samples collected from 5 min to 24 h following delivery. Using ¹H-NMR, we identified 14 metabolites that significantly differed between maternal and fetal placental...