Hepatic uptake of epirubicin by isolated rat hepatocytes and its biliary excretion after intravenous infusion in rats - Shin, Dae Hwan; Park, Seong Hyeok; Jeong, Sung Woo; Park, Chun-Woong; Han, Kun; Chung, Youn Bok (Archives of pharmacal research, 2014)
Keywords: Animals; antibiotics; Antibiotics, Antineoplastic - administration & dosage; Antibiotics, Antineoplastic - blood; Antibiotics, Antineoplastic - pharmacokinetics; bile; Bile - metabolism; carcinoma; Cells, Cultured; epirubicin; Epirubicin - administration & dosage; Epirubicin - blood; Epirubicin - pharmacokinetics; excretion; hepatocytes; Hepatocytes - metabolism; Infusions, Intravenous; intravenous injection; liver; Liver - metabolism; Male; Medicine; Metabolic Clearance Rate; metabolic inhibitors; Organic Anion Transporters - metabolism; Pharmacology/Toxicology; Pharmacy; polypeptides; rats; Rats, Sprague-Dawley; Research Article; rotenone; Tissue Distribution; transporters; uptake mechanisms; 약학; Isolated hepatocytes; Infusion; Hepatobiliary transport; Epirubicin; Bile excretion