Abnormalities of Mitochondrial Dynamics in Neurodegenerative Diseases

• Published in: Antioxidants Vol. 6; no. 2; p. 25
• Main Authors: Gao, Ju, Wang, Luwen, Liu, Jingyi, Xie, Fei, Su, Bo, Wang, Xinglong
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 05.04.2017; MDPI
• Subjects: Alzheimer's disease; Amyotrophic lateral sclerosis; Central nervous system; Disease; Huntington's disease; Mitochondria; Mitochondrial DNA; mitochondrial dynamics; mitochondrial dysfunction; mitochondrial fusion and fission; mitochondrial trafficking; Molecular modelling; Movement disorders; Nervous system; neurodegeneration; Neurodegenerative diseases; Neurological diseases; Organelles; Parkinson's disease; Review; Structure-function relationships; neurodegenerative diseases; Alzheimer’s disease; mitochondrial trafficking; neurodegeneration; Huntington’s disease; mitochondrial dysfunction; mitochondrial fusion and fission; amyotrophic lateral sclerosis; Parkinson’s disease; mitochondrial dynamics

Neurodegenerative diseases are incurable and devastating neurological disorders characterized by the progressive loss of the structure and function of neurons in the central nervous system or peripheral nervous system. Mitochondria, organelles found in most eukaryotic cells, are essential for neuron...