Bilateral Whisker Representations in the Primary Somatosensory Cortex in Robo3cKO Mice Are Reflected in the Primary Motor Cortex

• Published in: Neuroscience Vol. 544; pp. 128 - 137
• Main Authors: Tsytsarev, Vassiliy, Plachez, Céline, Zhao, Shuxin, O'Connor, Daniel H., Erzurumlu, Reha S.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 19.04.2024
• Subjects: Animals; barrel cortex; bifacial cortical maps; Mice; Motor Cortex - physiology; premotor/prefrontal cortex; Somatosensory Cortex - physiology; Thalamus - diagnostic imaging; Trigeminal Nuclei; Vibrissae - physiology; voltage-sensitive dye imaging; Ab; RT; M1; bifacial cortical maps; MRI; cKO; Ms; PFA; VSDi; barrel cortex; SD; voltage-sensitive dye imaging; VPM; PMPF; WT; VGlut2; DCC; DAPI; ACSF; HGPPS; ROBO; ROI; POM; fMRI; PB; TCA; PrV; AAV; premotor/prefrontal cortex; TMS; S1; S2

•Imaging Robo3cKO mouse cortex with bilateral whisker representation.•S1 to M1 and Prefrontal Cortex projections.•Bilateral whisker representation in the M1 cortex of Robo3cKO mice. In Robo3cKO mice, midline crossing defects of the trigeminothalamic projections from the trigeminal principal sensory...