Effect of exercise on the plasma vesicular proteome: a methodological study comparing acoustic trapping and centrifugation

• Published in: Lab on a chip Vol. 18; no. 20; pp. 3101 - 3111
• Main Authors: Bryl-Górecka, Paulina, Sathanoori, Ramasri, Al-Mashat, Mariam, Olde, Björn, Jögi, Jonas, Evander, Mikael, Laurell, Thomas, Erlinge, David
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 2018
• Subjects: Acoustic coupling; Acoustics; Basic Medicine; Biomarkers; Blood plasma; Cell and Molecular Biology; Cell- och molekylärbiologi; Cellular communication; Centrifugation; Engineering and Technology; Exercise; Extracellular Vesicles - metabolism; Flow cytometry; Flow stability; High speed; Humans; Medical and Health Sciences; Medical Engineering; Medical Laboratory and Measurements Technologies; Medical Laboratory Technologies; Medicin och hälsovetenskap; Medicinsk laboratorie- och mätteknik; Medicinsk laboratorieteknik; Medicinska och farmaceutiska grundvetenskaper; Medicinteknik; Physical exercise; Plasma - cytology; Proteins; Proteomics; Proteomics - methods; Standing waves; Teknik; Trapping; Vesicles

Extracellular vesicles (EVs) are a heterogeneous group of actively released vesicles originating from a wide range of cell types. Characterization of these EVs and their proteomes in the human plasma provides a novel approach in clinical diagnostics, as they reflect physiological and pathological st...