Congenital pneumonia with sepsis caused by intrauterine infection of Ureaplasma parvum in a term newborn: a first case report

• Published in: Journal of perinatology Vol. 30; no. 5; pp. 359 - 362
• Main Authors: Morioka, I, Fujibayashi, H, Enoki, E, Yokoyama, N, Yokozaki, H, Matsuo, M
• Format: Journal Article
• Language: English
• Published: New York Nature Publishing Group US 01.05.2010; Nature Publishing Group
• Subjects: 692/420/256/1980; 692/699/1785; 692/699/255/1318; 692/700/1720; Autopsies; Autopsy; Bacterial pneumonia; Care and treatment; Case reports; Case studies; Chorioamnionitis - microbiology; Diagnosis; Fatal Outcome; Female; Health aspects; Humans; Infant, Newborn; Infants (Newborn); Infections; Male; Medicine; Medicine & Public Health; Mycoplasmatales; Neonates; Pathogenesis; Pediatric Surgery; Pediatrics; perinatal-neonatal-case-presentation; Pneumonia; Pneumonia, Bacterial - congenital; Pneumonia, Bacterial - diagnosis; Pneumonia, Bacterial - therapy; Pregnancy; Pregnancy Complications, Infectious - microbiology; Risk factors; Sepsis; Sepsis - congenital; Sepsis - diagnosis; Sepsis - therapy; Ureaplasma; Ureaplasma Infections - congenital; Ureaplasma Infections - diagnosis; Ureaplasma Infections - therapy; Ureaplasma parvum; Japan; intrauterine infection; pneumonia; multiplex polymerase chain reaction; term newborn; sepsis
• ISSN: 0743-8346; 1476-5543
• DOI: 10.1038/jp.2009.145

We present an autopsy case of intrauterine pneumonia in a term newborn in whom Ureaplasma parvum was confirmed by PCR examinations, including a novel diagnostic tool for detecting pathogens that caused neonatal infections using multiplex PCR. This is the first report of U. parvum being implicated in the pathogenesis of congenital pneumonia with sepsis in a term newborn.