Early production of thymic stromal lymphopoietin precedes infiltration of dendritic cells expressing its receptor in allergen-induced late phase cutaneous responses in atopic subjects
Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)-7-like cytokine that triggers dendritic cell-mediated T helper (Th)2 inflammatory responses through a receptor consisting of a heterodimer of the IL-7 receptor alpha (IL-7Rα) chain and the TSLP receptor (TSLPR), which resembles the cytokine...
Saved in:
| Published in | Allergy (Copenhagen) Vol. 64; no. 7; pp. 1014 - 1022 |
|---|---|
| Main Authors | , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Oxford, UK
Oxford, UK : Blackwell Publishing Ltd
01.07.2009
Blackwell Publishing Ltd |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0105-4538 1398-9995 1398-9995 |
| DOI | 10.1111/j.1398-9995.2009.01947.x |
Cover
| Abstract | Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)-7-like cytokine that triggers dendritic cell-mediated T helper (Th)2 inflammatory responses through a receptor consisting of a heterodimer of the IL-7 receptor alpha (IL-7Rα) chain and the TSLP receptor (TSLPR), which resembles the cytokine receptor common gamma chain. Dendritic cells activated by TSLP prime development of CD4⁺ T cells into Th2 cells contributing to the pathogenesis of allergic inflammation. We hypothesized that allergen exposure induces expression of TSLP and results in recruitment of TSLPR bearing cells in the cutaneous allergen-induced late-phase reaction (LPR) in atopic subjects. Skin biopsies were obtained from atopic subjects (n = 9) at various times after cutaneous allergen challenge. In situ hybridization and immunohistochemistry were used to determine TSLP mRNA expression and to measure infiltration of TSLPR⁺ DC in skin LPR. RT-PCR and flow cytometry were employed to analyse TSLPR expression on isolated blood DC. Allergen-induced skin TSLP expression occurred as early as 1 h after allergen challenge, whereas TSLPR⁺ and CD11c⁺ cells infiltrated relatively late (24-48 h). The majority of TSLPR⁺ cells were DC co-expressing blood DC antigen-1 (BDCA-1) or BDCA-2. Freshly isolated blood DC expressed both TSLPR and IL-7Rα chains. Maturation and stimulation with TSLP or polyriboinosinic-polyribocytidylic acid in vitro upregulated the expression of both TSLPR and IL-7Rα chains in DC but not in chemoattractant receptor-homologous molecule expressed on Th2 cells⁺ CD4⁺ T cells. The data suggest that TSLP plays a role in augmenting, through DC recruitment and activation, the development of Th2-type T cells in allergic inflammation. |
|---|---|
| AbstractList | Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)-7-like cytokine that triggers dendritic cell-mediated T helper (Th)2 inflammatory responses through a receptor consisting of a heterodimer of the IL-7 receptor alpha (IL-7Rα) chain and the TSLP receptor (TSLPR), which resembles the cytokine receptor common gamma chain. Dendritic cells activated by TSLP prime development of CD4⁺ T cells into Th2 cells contributing to the pathogenesis of allergic inflammation. We hypothesized that allergen exposure induces expression of TSLP and results in recruitment of TSLPR bearing cells in the cutaneous allergen-induced late-phase reaction (LPR) in atopic subjects. Skin biopsies were obtained from atopic subjects (n = 9) at various times after cutaneous allergen challenge. In situ hybridization and immunohistochemistry were used to determine TSLP mRNA expression and to measure infiltration of TSLPR⁺ DC in skin LPR. RT-PCR and flow cytometry were employed to analyse TSLPR expression on isolated blood DC. Allergen-induced skin TSLP expression occurred as early as 1 h after allergen challenge, whereas TSLPR⁺ and CD11c⁺ cells infiltrated relatively late (24-48 h). The majority of TSLPR⁺ cells were DC co-expressing blood DC antigen-1 (BDCA-1) or BDCA-2. Freshly isolated blood DC expressed both TSLPR and IL-7Rα chains. Maturation and stimulation with TSLP or polyriboinosinic-polyribocytidylic acid in vitro upregulated the expression of both TSLPR and IL-7Rα chains in DC but not in chemoattractant receptor-homologous molecule expressed on Th2 cells⁺ CD4⁺ T cells. The data suggest that TSLP plays a role in augmenting, through DC recruitment and activation, the development of Th2-type T cells in allergic inflammation. Background: Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)-7-like cytokine that triggers dendritic cell-mediated T helper (Th)2 inflammatory responses through a receptor consisting of a heterodimer of the IL-7 receptor alpha (IL-7R alpha ) chain and the TSLP receptor (TSLPR), which resembles the cytokine receptor common gamma chain. Dendritic cells activated by TSLP prime development of CD4+ T cells into Th2 cells contributing to the pathogenesis of allergic inflammation. We hypothesized that allergen exposure induces expression of TSLP and results in recruitment of TSLPR bearing cells in the cutaneous allergen-induced late-phase reaction (LPR) in atopic subjects.Methods: Skin biopsies were obtained from atopic subjects (n = 9) at various times after cutaneous allergen challenge. In situ hybridization and immunohistochemistry were used to determine TSLP mRNA expression and to measure infiltration of TSLPR+ DC in skin LPR. RT-PCR and flow cytometry were employed to analyse TSLPR expression on isolated blood DC.Results: Allergen-induced skin TSLP expression occurred as early as 1 h after allergen challenge, whereas TSLPR+ and CD11c+ cells infiltrated relatively late (24-48 h). The majority of TSLPR+ cells were DC co-expressing blood DC antigen-1 (BDCA-1) or BDCA-2. Freshly isolated blood DC expressed both TSLPR and IL-7R alpha chains. Maturation and stimulation with TSLP or polyriboinosinic-polyribocytidylic acid in vitro upregulated the expression of both TSLPR and IL-7R alpha chains in DC but not in chemoattractant receptor-homologous molecule expressed on Th2 cells+ CD4+ T cells.Conclusion: The data suggest that TSLP plays a role in augmenting, through DC recruitment and activation, the development of Th2-type T cells in allergic inflammation. Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)-7-like cytokine that triggers dendritic cell-mediated T helper (Th)2 inflammatory responses through a receptor consisting of a heterodimer of the IL-7 receptor alpha (IL-7Ralpha) chain and the TSLP receptor (TSLPR), which resembles the cytokine receptor common gamma chain. Dendritic cells activated by TSLP prime development of CD4(+) T cells into Th2 cells contributing to the pathogenesis of allergic inflammation. We hypothesized that allergen exposure induces expression of TSLP and results in recruitment of TSLPR bearing cells in the cutaneous allergen-induced late-phase reaction (LPR) in atopic subjects.BACKGROUNDThymic stromal lymphopoietin (TSLP) is an interleukin (IL)-7-like cytokine that triggers dendritic cell-mediated T helper (Th)2 inflammatory responses through a receptor consisting of a heterodimer of the IL-7 receptor alpha (IL-7Ralpha) chain and the TSLP receptor (TSLPR), which resembles the cytokine receptor common gamma chain. Dendritic cells activated by TSLP prime development of CD4(+) T cells into Th2 cells contributing to the pathogenesis of allergic inflammation. We hypothesized that allergen exposure induces expression of TSLP and results in recruitment of TSLPR bearing cells in the cutaneous allergen-induced late-phase reaction (LPR) in atopic subjects.Skin biopsies were obtained from atopic subjects (n = 9) at various times after cutaneous allergen challenge. In situ hybridization and immunohistochemistry were used to determine TSLP mRNA expression and to measure infiltration of TSLPR(+) DC in skin LPR. RT-PCR and flow cytometry were employed to analyse TSLPR expression on isolated blood DC.METHODSSkin biopsies were obtained from atopic subjects (n = 9) at various times after cutaneous allergen challenge. In situ hybridization and immunohistochemistry were used to determine TSLP mRNA expression and to measure infiltration of TSLPR(+) DC in skin LPR. RT-PCR and flow cytometry were employed to analyse TSLPR expression on isolated blood DC.Allergen-induced skin TSLP expression occurred as early as 1 h after allergen challenge, whereas TSLPR(+) and CD11c(+) cells infiltrated relatively late (24-48 h). The majority of TSLPR(+) cells were DC co-expressing blood DC antigen-1 (BDCA-1) or BDCA-2. Freshly isolated blood DC expressed both TSLPR and IL-7Ralpha chains. Maturation and stimulation with TSLP or polyriboinosinic-polyribocytidylic acid in vitro upregulated the expression of both TSLPR and IL-7Ralpha chains in DC but not in chemoattractant receptor-homologous molecule expressed on Th2 cells(+) CD4(+) T cells.RESULTSAllergen-induced skin TSLP expression occurred as early as 1 h after allergen challenge, whereas TSLPR(+) and CD11c(+) cells infiltrated relatively late (24-48 h). The majority of TSLPR(+) cells were DC co-expressing blood DC antigen-1 (BDCA-1) or BDCA-2. Freshly isolated blood DC expressed both TSLPR and IL-7Ralpha chains. Maturation and stimulation with TSLP or polyriboinosinic-polyribocytidylic acid in vitro upregulated the expression of both TSLPR and IL-7Ralpha chains in DC but not in chemoattractant receptor-homologous molecule expressed on Th2 cells(+) CD4(+) T cells.The data suggest that TSLP plays a role in augmenting, through DC recruitment and activation, the development of Th2-type T cells in allergic inflammation.CONCLUSIONThe data suggest that TSLP plays a role in augmenting, through DC recruitment and activation, the development of Th2-type T cells in allergic inflammation. Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)-7-like cytokine that triggers dendritic cell-mediated T helper (Th)2 inflammatory responses through a receptor consisting of a heterodimer of the IL-7 receptor alpha (IL-7Rα) chain and the TSLP receptor (TSLPR), which resembles the cytokine receptor common gamma chain. Dendritic cells activated by TSLP prime development of CD4+ T cells into Th2 cells contributing to the pathogenesis of allergic inflammation. We hypothesized that allergen exposure induces expression of TSLP and results in recruitment of TSLPR bearing cells in the cutaneous allergen-induced late-phase reaction (LPR) in atopic subjects. Skin biopsies were obtained from atopic subjects ( n = 9) at various times after cutaneous allergen challenge. In situ hybridization and immunohistochemistry were used to determine TSLP mRNA expression and to measure infiltration of TSLPR+ DC in skin LPR. RT-PCR and flow cytometry were employed to analyse TSLPR expression on isolated blood DC. Allergen-induced skin TSLP expression occurred as early as 1 h after allergen challenge, whereas TSLPR+ and CD11c+ cells infiltrated relatively late (24-48 h). The majority of TSLPR+ cells were DC co-expressing blood DC antigen-1 (BDCA-1) or BDCA-2. Freshly isolated blood DC expressed both TSLPR and IL-7Rα chains. Maturation and stimulation with TSLP or polyriboinosinic-polyribocytidylic acid in vitro upregulated the expression of both TSLPR and IL-7Rα chains in DC but not in chemoattractant receptor-homologous molecule expressed on Th2 cells+ CD4+ T cells. The data suggest that TSLP plays a role in augmenting, through DC recruitment and activation, the development of Th2-type T cells in allergic inflammation. [PUBLICATION ABSTRACT] Background: Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)‐7‐like cytokine that triggers dendritic cell‐mediated T helper (Th)2 inflammatory responses through a receptor consisting of a heterodimer of the IL‐7 receptor alpha (IL‐7Rα) chain and the TSLP receptor (TSLPR), which resembles the cytokine receptor common gamma chain. Dendritic cells activated by TSLP prime development of CD4+ T cells into Th2 cells contributing to the pathogenesis of allergic inflammation. We hypothesized that allergen exposure induces expression of TSLP and results in recruitment of TSLPR bearing cells in the cutaneous allergen‐induced late‐phase reaction (LPR) in atopic subjects. Methods: Skin biopsies were obtained from atopic subjects (n = 9) at various times after cutaneous allergen challenge. In situ hybridization and immunohistochemistry were used to determine TSLP mRNA expression and to measure infiltration of TSLPR+ DC in skin LPR. RT‐PCR and flow cytometry were employed to analyse TSLPR expression on isolated blood DC. Results: Allergen‐induced skin TSLP expression occurred as early as 1 h after allergen challenge, whereas TSLPR+ and CD11c+ cells infiltrated relatively late (24–48 h). The majority of TSLPR+ cells were DC co‐expressing blood DC antigen‐1 (BDCA‐1) or BDCA‐2. Freshly isolated blood DC expressed both TSLPR and IL‐7Rα chains. Maturation and stimulation with TSLP or polyriboinosinic–polyribocytidylic acid in vitro upregulated the expression of both TSLPR and IL‐7Rα chains in DC but not in chemoattractant receptor‐homologous molecule expressed on Th2 cells+ CD4+ T cells. Conclusion: The data suggest that TSLP plays a role in augmenting, through DC recruitment and activation, the development of Th2‐type T cells in allergic inflammation. Background: Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)‐7‐like cytokine that triggers dendritic cell‐mediated T helper (Th)2 inflammatory responses through a receptor consisting of a heterodimer of the IL‐7 receptor alpha (IL‐7Rα) chain and the TSLP receptor (TSLPR), which resembles the cytokine receptor common gamma chain. Dendritic cells activated by TSLP prime development of CD4 + T cells into Th2 cells contributing to the pathogenesis of allergic inflammation. We hypothesized that allergen exposure induces expression of TSLP and results in recruitment of TSLPR bearing cells in the cutaneous allergen‐induced late‐phase reaction (LPR) in atopic subjects. Methods: Skin biopsies were obtained from atopic subjects ( n = 9) at various times after cutaneous allergen challenge. In situ hybridization and immunohistochemistry were used to determine TSLP mRNA expression and to measure infiltration of TSLPR + DC in skin LPR. RT‐PCR and flow cytometry were employed to analyse TSLPR expression on isolated blood DC. Results: Allergen‐induced skin TSLP expression occurred as early as 1 h after allergen challenge, whereas TSLPR + and CD11c + cells infiltrated relatively late (24–48 h). The majority of TSLPR + cells were DC co‐expressing blood DC antigen‐1 (BDCA‐1) or BDCA‐2. Freshly isolated blood DC expressed both TSLPR and IL‐7Rα chains. Maturation and stimulation with TSLP or polyriboinosinic–polyribocytidylic acid in vitro upregulated the expression of both TSLPR and IL‐7Rα chains in DC but not in chemoattractant receptor‐homologous molecule expressed on Th2 cells + CD4 + T cells. Conclusion: The data suggest that TSLP plays a role in augmenting, through DC recruitment and activation, the development of Th2‐type T cells in allergic inflammation. Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)-7-like cytokine that triggers dendritic cell-mediated T helper (Th)2 inflammatory responses through a receptor consisting of a heterodimer of the IL-7 receptor alpha (IL-7Ralpha) chain and the TSLP receptor (TSLPR), which resembles the cytokine receptor common gamma chain. Dendritic cells activated by TSLP prime development of CD4(+) T cells into Th2 cells contributing to the pathogenesis of allergic inflammation. We hypothesized that allergen exposure induces expression of TSLP and results in recruitment of TSLPR bearing cells in the cutaneous allergen-induced late-phase reaction (LPR) in atopic subjects. Skin biopsies were obtained from atopic subjects (n = 9) at various times after cutaneous allergen challenge. In situ hybridization and immunohistochemistry were used to determine TSLP mRNA expression and to measure infiltration of TSLPR(+) DC in skin LPR. RT-PCR and flow cytometry were employed to analyse TSLPR expression on isolated blood DC. Allergen-induced skin TSLP expression occurred as early as 1 h after allergen challenge, whereas TSLPR(+) and CD11c(+) cells infiltrated relatively late (24-48 h). The majority of TSLPR(+) cells were DC co-expressing blood DC antigen-1 (BDCA-1) or BDCA-2. Freshly isolated blood DC expressed both TSLPR and IL-7Ralpha chains. Maturation and stimulation with TSLP or polyriboinosinic-polyribocytidylic acid in vitro upregulated the expression of both TSLPR and IL-7Ralpha chains in DC but not in chemoattractant receptor-homologous molecule expressed on Th2 cells(+) CD4(+) T cells. The data suggest that TSLP plays a role in augmenting, through DC recruitment and activation, the development of Th2-type T cells in allergic inflammation. |
| Author | Liu, Y Corrigan, C.J Jayaratnam, A Wang, Y Ying, S Kay, A.B Phipps, S Meng, Q Lee, T.H de Waal Malefyt, R |
| Author_xml | – sequence: 1 fullname: Corrigan, C.J – sequence: 2 fullname: Jayaratnam, A – sequence: 3 fullname: Wang, Y – sequence: 4 fullname: Liu, Y – sequence: 5 fullname: de Waal Malefyt, R – sequence: 6 fullname: Meng, Q – sequence: 7 fullname: Kay, A.B – sequence: 8 fullname: Phipps, S – sequence: 9 fullname: Lee, T.H – sequence: 10 fullname: Ying, S |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/19187393$$D View this record in MEDLINE/PubMed |
| BookMark | eNqNks1uGyEQgFGVqnHcvkKLemhO68KyGDi0UhSlP5KlHtqcEd5lbSwWtsCq9pP19QJ2kkMOTbks0n7fzDAzF-DMeacBgBgtcD4fdwtMBK-EEHRRIyQWCIuGLfYvwOzxxxmYIYxo1VDCz8FFjDuEEKsFegXOscCcEUFm4O-NCvYAx-C7qU3GO-h7mLaHwbQwpuAHZaE9DOPWj97oZFxGdas7HaFxvbEpqAer064LJmWx1dZGqPcZjdG4DTQpwqKNyYfsQWWtDhvtKuNyWt1Bq5KG41ZFDdspKaf9VIw4ehePqaBKfiw1TeudblN8DV72ykb95v47B7dfbn5df6tWP75-v75aVS1tGKs47zihAi9Z0_RUoK4XQtG-U5orvOYN0x1FiDRN21OFGOY1QWK9pj2huaWoJnNweYqbO_R70jHJwcTyvlONkhFCGVrmXs7Bh3-SzbIWDNf4WbAuY2K8gO-fgDs_BZefK7FYckEoZRl6ew9N60F3cgxmUOEgH0acgc8noA0-xqB72Zp0HFqenbESI1l2Su5kWR1ZVqeUIORxp-Q-B-BPAjzmeF79dFL_GKsP_-3Jq9Wq3LL_7uT3yku1CSbK2581wgThJeE1JeQOtJrwdw |
| CitedBy_id | crossref_primary_10_1056_NEJMoa1402895 crossref_primary_10_2332_allergolint_11_RAI_0395 crossref_primary_10_1111_vde_12199 crossref_primary_10_1038_jid_2015_318 crossref_primary_10_1164_rccm_201508_1623OC crossref_primary_10_1016_j_anai_2011_01_004 crossref_primary_10_4049_jimmunol_1100355 crossref_primary_10_2340_actadv_v102_2925 crossref_primary_10_1111_pai_12482 crossref_primary_10_1038_mi_2009_134 crossref_primary_10_1016_j_coi_2010_10_020 crossref_primary_10_1097_ICO_0000000000001832 crossref_primary_10_1007_s12026_012_8264_z crossref_primary_10_1155_2014_231036 crossref_primary_10_1038_mi_2010_19 crossref_primary_10_1097_MOP_0b013e32834cad0a crossref_primary_10_3390_cells11101683 crossref_primary_10_1016_j_jaci_2011_03_043 crossref_primary_10_1111_all_12435 crossref_primary_10_5667_tang_2016_0021 crossref_primary_10_3390_biom14040401 crossref_primary_10_17116_klinderma20151424_10 crossref_primary_10_4049_jimmunol_1800709 crossref_primary_10_1111_j_1365_2222_2010_03684_x crossref_primary_10_1016_j_jaci_2012_07_010 crossref_primary_10_1016_j_clim_2020_108421 crossref_primary_10_1111_imr_12632 crossref_primary_10_1111_cea_12451 crossref_primary_10_1111_1346_8138_16652 crossref_primary_10_1111_bjd_13621 crossref_primary_10_1016_j_jaci_2013_06_033 |
| Cites_doi | 10.1038/ni1247 10.1111/j.1365-2230.2005.01980.x 10.1157/13091042 10.1016/j.immuni.2006.06.004 10.4049/jimmunol.147.3.816 10.1038/ni805 10.4049/jimmunol.141.12.4158 10.1016/j.immuni.2006.03.019 10.4049/jimmunol.176.2.966 10.1046/j.1365-2222.2002.01375.x 10.4049/jimmunol.174.12.8183 10.1056/NEJM200101043440106 10.1084/jem.20041503 10.1084/jem.20031975 10.1038/ni1360 10.1084/jem.20050199 10.1111/j.1398-9995.2005.00708.x 10.1038/nri1776 10.4049/jimmunol.163.7.3976 10.1084/jem.192.5.659 10.1136/thorax.56.11.823 10.1038/76923 10.4049/jimmunol.167.1.336 10.1016/j.jaci.2004.11.043 10.4049/jimmunol.174.8.5082 10.4049/jimmunol.158.10.5050 10.1165/rcmb.2004-0279OC |
| ContentType | Journal Article |
| Copyright | 2009 John Wiley & Sons A/S Journal compilation © 2009 Blackwell Munksgaard |
| Copyright_xml | – notice: 2009 John Wiley & Sons A/S – notice: Journal compilation © 2009 Blackwell Munksgaard |
| DBID | FBQ AAYXX CITATION CGR CUY CVF ECM EIF NPM 7T5 H94 K9. 7S9 L.6 7X8 |
| DOI | 10.1111/j.1398-9995.2009.01947.x |
| DatabaseName | AGRIS CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Immunology Abstracts AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) AGRICOLA AGRICOLA - Academic MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Immunology Abstracts AGRICOLA AGRICOLA - Academic MEDLINE - Academic |
| DatabaseTitleList | AIDS and Cancer Research Abstracts MEDLINE - Academic AIDS and Cancer Research Abstracts CrossRef MEDLINE AGRICOLA |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: FBQ name: AGRIS url: http://www.fao.org/agris/Centre.asp?Menu_1ID=DB&Menu_2ID=DB1&Language=EN&Content=http://www.fao.org/agris/search?Language=EN sourceTypes: Publisher |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1398-9995 |
| EndPage | 1022 |
| ExternalDocumentID | 1738476941 19187393 10_1111_j_1398_9995_2009_01947_x ALL1947 US201301638253 |
| Genre | article Research Support, Non-U.S. Gov't Journal Article |
| GroupedDBID | .3N .GA .GJ .Y3 05W 0R~ 10A 1OB 1OC 23M 2WC 31~ 33P 36B 3SF 4.4 50Y 50Z 51W 51X 52M 52N 52O 52P 52R 52S 52T 52U 52V 52W 52X 53G 5GY 5HH 5LA 5RE 5VS 66C 702 7PT 8-0 8-1 8-3 8-4 8-5 8F7 8UM 930 A01 A03 AAESR AAEVG AAHHS AAHQN AAIPD AAKAS AAMNL AANHP AANLZ AAONW AASGY AAXRX AAYCA AAZKR ABCQN ABCUV ABEML ABJNI ABLJU ABOCM ABPVW ABQWH ABXGK ACAHQ ACBWZ ACCFJ ACCZN ACGFS ACGOF ACMXC ACPOU ACPRK ACRPL ACSCC ACXBN ACXQS ACYXJ ADBBV ADBTR ADEOM ADIZJ ADKYN ADMGS ADNMO ADOZA ADXAS ADZCM ADZMN AEEZP AEIGN AEIMD AENEX AEQDE AEUYR AFBPY AFEBI AFFNX AFFPM AFGKR AFRAH AFWVQ AFZJQ AGHNM AHBTC AHEFC AHMBA AIACR AITYG AIURR AIWBW AJBDE ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN ALVPJ AMBMR AMYDB AOETA ATUGU AZBYB AZFZN AZVAB BAFTC BAWUL BDRZF BFHJK BHBCM BMXJE BROTX BRXPI BY8 C45 CAG COF CS3 D-6 D-7 D-E D-F DC6 DCZOG DPXWK DR2 DRFUL DRMAN DRSTM E3Z EBS EJD EMOBN EX3 F00 F01 F04 F5P FBQ FEDTE FUBAC FZ0 G-S G.N GODZA H.X HF~ HGLYW HVGLF HZI HZ~ IHE IX1 J0M K48 KBYEO LATKE LC2 LC3 LEEKS LH4 LITHE LOXES LP6 LP7 LUTES LW6 LYRES MEWTI MK4 MRFUL MRMAN MRSTM MSFUL MSMAN MSSTM MXFUL MXMAN MXSTM N04 N05 N9A NF~ O66 O9- OIG OK1 OVD P2P P2W P2X P2Z P4B P4D P6G PALCI PQQKQ Q.N Q11 QB0 R.K RIWAO RJQFR ROL RX1 SAMSI SUPJJ TEORI TR2 UB1 V9Y W8V W99 WBKPD WHWMO WIH WIJ WIK WIN WOHZO WOW WQJ WVDHM WXI WXSBR XG1 Y6R ZGI ZXP ZZTAW ~IA ~KM ~WT 24P AEUQT AFPWT DIK ESX WRC WUP AAYXX AEYWJ AGQPQ AGYGG CITATION CGR CUY CVF ECM EIF NPM 7T5 AAMMB AEFGJ AGXDD AIDQK AIDYY H94 K9. 7S9 L.6 7X8 |
| ID | FETCH-LOGICAL-c5477-88d835916744f590df99a5fdae8a1b847ed500344cf5a07182309bb5f35019023 |
| IEDL.DBID | DR2 |
| ISSN | 0105-4538 1398-9995 |
| IngestDate | Fri Jul 11 00:04:08 EDT 2025 Fri Jul 11 06:17:52 EDT 2025 Fri Jul 11 08:54:10 EDT 2025 Fri Jul 25 05:50:59 EDT 2025 Wed Feb 19 01:44:10 EST 2025 Tue Jul 01 04:14:47 EDT 2025 Thu Apr 24 23:03:16 EDT 2025 Wed Jan 22 16:48:56 EST 2025 Thu Apr 03 09:44:32 EDT 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 7 |
| Language | English |
| License | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c5477-88d835916744f590df99a5fdae8a1b847ed500344cf5a07182309bb5f35019023 |
| Notes | http://dx.doi.org/10.1111/j.1398-9995.2009.01947.x ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Article-2 ObjectType-Feature-1 content type line 23 |
| PMID | 19187393 |
| PQID | 196893557 |
| PQPubID | 34098 |
| PageCount | 9 |
| ParticipantIDs | proquest_miscellaneous_733570639 proquest_miscellaneous_46297121 proquest_miscellaneous_20072781 proquest_journals_196893557 pubmed_primary_19187393 crossref_citationtrail_10_1111_j_1398_9995_2009_01947_x crossref_primary_10_1111_j_1398_9995_2009_01947_x wiley_primary_10_1111_j_1398_9995_2009_01947_x_ALL1947 fao_agris_US201301638253 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | July 2009 |
| PublicationDateYYYYMMDD | 2009-07-01 |
| PublicationDate_xml | – month: 07 year: 2009 text: July 2009 |
| PublicationDecade | 2000 |
| PublicationPlace | Oxford, UK |
| PublicationPlace_xml | – name: Oxford, UK – name: Denmark – name: Zurich |
| PublicationTitle | Allergy (Copenhagen) |
| PublicationTitleAlternate | Allergy |
| PublicationYear | 2009 |
| Publisher | Oxford, UK : Blackwell Publishing Ltd Blackwell Publishing Ltd |
| Publisher_xml | – name: Oxford, UK : Blackwell Publishing Ltd – name: Blackwell Publishing Ltd |
| References | 2004; 200 1997; 158 2001; 344 2001; 167 2006; 31 2005; 174 2006; 34 2005; 115 2002; 32 2006; 7 2002; 3 2006; 176 1999; 163 2006; 6 2000; 1 1988; 141 2005; 60 1991; 147 2006; 24 2005; 202 2005; 74 2005; 6 2005; 32 2000; 1925 2001; 56 Ying S (e_1_2_7_5_2) 1999; 163 e_1_2_7_9_2 Gaga M (e_1_2_7_3_2) 1991; 147 e_1_2_7_8_2 e_1_2_7_6_2 e_1_2_7_19_2 e_1_2_7_18_2 e_1_2_7_17_2 e_1_2_7_16_2 e_1_2_7_15_2 e_1_2_7_14_2 e_1_2_7_13_2 e_1_2_7_12_2 e_1_2_7_11_2 e_1_2_7_10_2 e_1_2_7_26_2 Frew AJ (e_1_2_7_2_2) 1988; 141 e_1_2_7_27_2 e_1_2_7_28_2 Soumelis V (e_1_2_7_7_2) 2002; 3 e_1_2_7_25_2 e_1_2_7_24_2 e_1_2_7_23_2 e_1_2_7_22_2 e_1_2_7_21_2 e_1_2_7_20_2 Ying S (e_1_2_7_4_2) 1997; 158 |
| References_xml | – volume: 202 start-page: 829 year: 2005 end-page: 839 article-title: A role for TSLP in the development of inflammation in an asthma model publication-title: J Exp Med – volume: 167 start-page: 336 year: 2001 end-page: 343 article-title: Human thymic stromal lymphopoietin preferentially stimulates myeloid cells publication-title: J Immunol – volume: 7 start-page: 709 year: 2006 end-page: 714 article-title: Thymic stromal lymphopoietin in normal and pathogenic T cell development and function publication-title: Nat Immunol – volume: 147 start-page: 816 year: 1991 end-page: 822 article-title: Eosinophil activation and T lymphocyte activation in allergen‐induced late phase reactions and classical delayed‐type hypersensitivity in man publication-title: J Immunol – volume: 176 start-page: 966 year: 2006 end-page: 973 article-title: Prostaglandin E2 is generally required for human dendritic cell migration and experts its effects via EP2 and EP4 receptors publication-title: J Immunol – volume: 24 start-page: 827 year: 2006 end-page: 838 article-title: Maintenance and polarization of human T 2 central memory T cells by thymic stromal lymphopoietin‐activated dendritic cells publication-title: Immunity – volume: 3 start-page: 6673 year: 2002 end-page: 6680 article-title: Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP publication-title: Nat Immunol – volume: 31 start-page: 89 year: 2006 end-page: 93 article-title: The pathophysiology of atopic eczema publication-title: Clin Exp Dermatol – volume: 34 start-page: 156 year: 2006 end-page: 170 article-title: New aspects on inflammation in allergic diseases publication-title: Allergol Immunopathol – volume: 200 start-page: 159 year: 2004 end-page: 168 article-title: A role of thymic stromal lymphopoietin in CD4+ T cell development publication-title: J Exp Med – volume: 115 start-page: 771 year: 2005 end-page: 778 article-title: Asthmatic bronchial epithelium activated by the proteolytic allergen Der p 1 increases selective dendritic cell recruitment publication-title: J Allergy Clin Immunol – volume: 174 start-page: 5082 year: 2005 end-page: 5091 article-title: CCL1–CCR8 interactions: an axis mediating the recruitment of T cells and Langerhans‐type dendritic cells to sites of atopic skin inflammation publication-title: J Immunol – volume: 158 start-page: 5050 year: 1997 end-page: 5057 article-title: Associations between IL‐13 and IL‐4 (mRNA and protein), VCAM‐1 expression and the infiltration of eosinophils, macrophages and T cells in allergen‐induced late‐phase cutaneous reactions in atopic subjects publication-title: J Immunol – volume: 6 start-page: 159 year: 2006 end-page: 164 article-title: Chemokines: more than just road signs publication-title: Nat Rev Immunol – volume: 32 start-page: 177 year: 2005 end-page: 184 article-title: Identification and characterization of human pulmonary dendritic cells publication-title: Am J Respir Cell Mol Bio – volume: 163 start-page: 3976 year: 1999 end-page: 3984 article-title: C‐C chemokines in allergen‐induced late phase cutaneous responses in atopic subjects: association of eotaxin with early 6‐hour eosinophils, and eotaxin‐2 and MCP‐4 with the later 24‐hour tissue eosinophilia, and relationship to basophils and other C‐C chemokines (MCP‐3 and RANTES) publication-title: J Immunol – volume: 56 start-page: 823 year: 2001 end-page: 826 article-title: Rapid dendritic cell recruitment to the bronchial mucosa of patients with atopic asthma in response to local allergen challenge publication-title: Thorax – volume: 24 start-page: 673 year: 2006 end-page: 675 article-title: Tweaking of memory T helper 2 cells by TSLP publication-title: Immunity – volume: 141 start-page: 4158 year: 1988 end-page: 4164 article-title: The relationship between CD4 lymphocytes, activated eosinophils and the magnitude of the allergen‐induced late phase skin reaction in man publication-title: J Immunol – volume: 32 start-page: 805 year: 2002 end-page: 810 article-title: Rapid response of circulating myeloid dendritic cells into inhaled allergen in asthmatic subjects publication-title: Clin Exp Allergy – volume: 6 start-page: 1047 year: 2005 end-page: 1053 article-title: Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice publication-title: Nat Immunol – volume: 74 start-page: 8183 year: 2005 end-page: 8190 article-title: Thymic stromal lymphopoietin (TSLP) expression is increased in asthmatic airways correlates with expression of Th2‐attracting chemokines and disease severity publication-title: J Immunol – volume: 1925 start-page: 659 year: 2000 end-page: 670 article-title: Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: formation of a functional heteromeric complex requires interleukin 7 receptor publication-title: J Exp Med – volume: 202 start-page: 541 year: 2005 end-page: 549 article-title: Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin publication-title: J Exp Med – volume: 1 start-page: 59 year: 2000 end-page: 64 article-title: Cloning of a receptor subunit required for signalling by thymic stromal lymphopoietin publication-title: Nat Immunol – volume: 60 start-page: 271 year: 2005 end-page: 282 article-title: Dendritic cells and the regulation of the allergic immune response publication-title: Allergy – volume: 344 start-page: 30 year: 2001 end-page: 37 article-title: Allergy and allergic diseases publication-title: N Engl J Med – ident: e_1_2_7_10_2 doi: 10.1038/ni1247 – ident: e_1_2_7_19_2 doi: 10.1111/j.1365-2230.2005.01980.x – ident: e_1_2_7_25_2 doi: 10.1157/13091042 – ident: e_1_2_7_26_2 doi: 10.1016/j.immuni.2006.06.004 – volume: 147 start-page: 816 year: 1991 ident: e_1_2_7_3_2 article-title: Eosinophil activation and T lymphocyte activation in allergen‐induced late phase reactions and classical delayed‐type hypersensitivity in man publication-title: J Immunol doi: 10.4049/jimmunol.147.3.816 – volume: 3 start-page: 6673 year: 2002 ident: e_1_2_7_7_2 article-title: Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP publication-title: Nat Immunol doi: 10.1038/ni805 – volume: 141 start-page: 4158 year: 1988 ident: e_1_2_7_2_2 article-title: The relationship between CD4+ lymphocytes, activated eosinophils and the magnitude of the allergen‐induced late phase skin reaction in man publication-title: J Immunol doi: 10.4049/jimmunol.141.12.4158 – ident: e_1_2_7_12_2 doi: 10.1016/j.immuni.2006.03.019 – ident: e_1_2_7_24_2 doi: 10.4049/jimmunol.176.2.966 – ident: e_1_2_7_15_2 doi: 10.1046/j.1365-2222.2002.01375.x – ident: e_1_2_7_8_2 doi: 10.4049/jimmunol.174.12.8183 – ident: e_1_2_7_6_2 doi: 10.1056/NEJM200101043440106 – ident: e_1_2_7_9_2 doi: 10.1084/jem.20041503 – ident: e_1_2_7_27_2 doi: 10.1084/jem.20031975 – ident: e_1_2_7_28_2 doi: 10.1038/ni1360 – ident: e_1_2_7_11_2 doi: 10.1084/jem.20050199 – ident: e_1_2_7_14_2 doi: 10.1111/j.1398-9995.2005.00708.x – ident: e_1_2_7_22_2 doi: 10.1038/nri1776 – volume: 163 start-page: 3976 year: 1999 ident: e_1_2_7_5_2 article-title: C‐C chemokines in allergen‐induced late phase cutaneous responses in atopic subjects: association of eotaxin with early 6‐hour eosinophils, and eotaxin‐2 and MCP‐4 with the later 24‐hour tissue eosinophilia, and relationship to basophils and other C‐C chemokines (MCP‐3 and RANTES) publication-title: J Immunol doi: 10.4049/jimmunol.163.7.3976 – ident: e_1_2_7_21_2 doi: 10.1084/jem.192.5.659 – ident: e_1_2_7_16_2 doi: 10.1136/thorax.56.11.823 – ident: e_1_2_7_20_2 doi: 10.1038/76923 – ident: e_1_2_7_13_2 doi: 10.4049/jimmunol.167.1.336 – ident: e_1_2_7_17_2 doi: 10.1016/j.jaci.2004.11.043 – ident: e_1_2_7_23_2 doi: 10.4049/jimmunol.174.8.5082 – volume: 158 start-page: 5050 year: 1997 ident: e_1_2_7_4_2 article-title: Associations between IL‐13 and IL‐4 (mRNA and protein), VCAM‐1 expression and the infiltration of eosinophils, macrophages and T cells in allergen‐induced late‐phase cutaneous reactions in atopic subjects publication-title: J Immunol doi: 10.4049/jimmunol.158.10.5050 – ident: e_1_2_7_18_2 doi: 10.1165/rcmb.2004-0279OC |
| SSID | ssj0007290 |
| Score | 2.1234343 |
| Snippet | Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)-7-like cytokine that triggers dendritic cell-mediated T helper (Th)2 inflammatory responses through... Background: Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)‐7‐like cytokine that triggers dendritic cell‐mediated T helper (Th)2 inflammatory... Background: Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)‐7‐like cytokine that triggers dendritic cell‐mediated T helper (Th)2 inflammatory... Background: Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)-7-like cytokine that triggers dendritic cell-mediated T helper (Th)2 inflammatory... |
| SourceID | proquest pubmed crossref wiley fao |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 1014 |
| SubjectTerms | Adolescent Adult agonists Allergens Allergens - immunology allergic inflammation Allergies Antigens, CD1 Antigens, Surface Antigens, Surface - immunology Antigens, Surface - metabolism biosynthesis CD4-Positive T-Lymphocytes CD4-Positive T-Lymphocytes - drug effects CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - metabolism Cellular biology Cytokines Cytokines - biosynthesis Cytokines - immunology Cytokines - pharmacology dendritic cells Dendritic Cells - drug effects Dendritic Cells - immunology Dendritic Cells - metabolism drug effects Glycoproteins Humans Hypersensitivity Hypersensitivity - immunology Hypersensitivity - metabolism Immune system immunology Interferon Inducers Interferon Inducers - pharmacology Interleukin-15 Interleukin-15 - pharmacology Interleukin-7 Interleukin-7 - pharmacology Lectins, C-Type Lectins, C-Type - immunology Lectins, C-Type - metabolism Lymphocytes Membrane Glycoproteins Membrane Glycoproteins - immunology Membrane Glycoproteins - metabolism metabolism Middle Aged Pathology pharmacology Poly I-C Poly I-C - pharmacology Receptors, Cytokine Receptors, Cytokine - agonists Receptors, Cytokine - immunology Receptors, Cytokine - metabolism Receptors, Immunologic Receptors, Immunologic - immunology Receptors, Immunologic - metabolism Receptors, Interleukin-7 Receptors, Interleukin-7 - agonists Receptors, Interleukin-7 - immunology Receptors, Interleukin-7 - metabolism Skin Skin - immunology Skin - pathology thymic stromal lymphopoietin Young Adult |
| Title | Early production of thymic stromal lymphopoietin precedes infiltration of dendritic cells expressing its receptor in allergen-induced late phase cutaneous responses in atopic subjects |
| URI | https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fj.1398-9995.2009.01947.x https://www.ncbi.nlm.nih.gov/pubmed/19187393 https://www.proquest.com/docview/196893557 https://www.proquest.com/docview/20072781 https://www.proquest.com/docview/46297121 https://www.proquest.com/docview/733570639 |
| Volume | 64 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1LT9wwELZaDlUvhT4J9OFDr1ltHo7jIyogVEEPbVfiZtmOTSOWJNokEu2Jn9C_07_TX8KMk126FUio6m2l9SRx5uEvnvE3hLxPk2kBMLsIneNIqq3TUHOWhmbqFIclIdaexPXkU3Y0Sz-estOx_gnPwgz8EKsNN_QMH6_RwZVu1508EeCsQrCRdhK-x_kE8WSUZEijv__5hkmKj9stACfgiZJ8vajn1gutrVQPnapvA6HrmNYvSoeb5Hw5naEW5XzSd3pifvzF9Ph_5rtFnozYle4NxvaUPLDVM_LoZMzOPye_PFsybQYSWVA4rR0FQ7goDW27RX0BwvPvYD51U5d41BqGWmML21Kw83I-MviiFETDwjdhoJhZaKm9HAp2qzNadi1FsaarFyBHsRkMniD9ffWzrODGtqBzANC0-QYLNDU9oF9b9yjjq4H9zajq6gafqte4D9W-ILPDg68fjsKxNURoWApGlecFQEeBRyhSx8S0cEIo5gplcxVpWHFtwTyboXFMAYrCdKLQmjnMowrAKS_JRlVXdptQm0URV1okQvHUaKtFHJmpVtxkucq5DQhfmoE0I286tu-Yyz--n0AzEjWDXT2F9JqRlwGJVpLNwB1yD5ltsDSpziDEy9mXGBPLCJljlgRkd2l-cgw0rYQAmiNFPg_Iu9W_ECFQOcPrxcsDSM2ju0ekWSx4FMMIescIniSMI5oNyKvB8G9mJKIcaRUDknnzvfdU5d7xMf7a-VfBXfJ4yO1h8fRrstEtevsGIGKn33rnvwbx6ln4 |
| linkProvider | Wiley-Blackwell |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3NbtQwELagSMCFf2goUB-47mrz4zg-VkC1wG4P0JV6s2zHaSPSJNokUtsTj8Dr8Do8CTNOdsuiVqoQt0jxJHFmPP7sGX9DyNsonKQAs9NRlnEk1dbRSHMWjcwkUxymhEA7Etf5QTxdRJ-O2NFQDgjPwvT8EOsNNxwZzl_jAMcN6c1RHgoYrUKwgXcSFuR8DIDyTgS4A1di779ccknxYcMFAAV8U5hspvVc-aSNuep2pqqrYOgmqnXT0v5DUqw61GejfBt3rR6bi7-4Hv9Tjx-RBwN8pXu9vT0mt2z5hNydDwH6p-SnI0ymdc8jCzqnVUbBFk5zQ5t2WZ2CcHEOFlTVVY6nraGpNTa1DQVTz4uBxBelwCGmrg4DxeBCQ-1Zn7NbHtO8bSiK1W21BDmK9WDwEOmv7z_yEl5sU1oAhqb1CczR1HQAgG3VoYxLCHYvo6qtavyqTuNWVPOMLPY_HL6bjobqECPDIrCrJEkBPQo8RRFlTEzSTAjFslTZRPkaJl2bMkdoaDKmAEhhRFFozTIMpQqAKs_JVlmVdptQG_s-V1qEQvHIaKtF4JuJVtzEiUq49Qhf2YE0A3U6VvAo5B9LKNCMRM1gYU8hnWbkmUf8tWTd04fcQGYbTE2qY_DycvE1wNgyouaAhR7ZWdmfHHxNI8GHJsiSzz2yu74LTgKV0_9efDzg1MS_vkUUB4L7AbSg17TgYcg4AlqPvOgt_7JHwk-QWdEjsbPfG3dV7s1mePXyXwV3yb3p4XwmZx8PPu-Q-32oD3OpX5GtdtnZ14AYW_3GeYLfgE1eFw |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3NbtQwELagSBUX_qGhQH3guqvNj-P4WAGrAtsKASv1ZtmOXaJuk2iTSIUTj8Dr8Do8CTNOdsuiVqoQt5XWk8SZ8cwXz_gbQl4m8SQHmJ2PnONIqq2TkeYsGZmJUxxCQqQ9ievhUXowT94ds-Oh_gnPwvT8EOsNN1wZ3l_jAq9zt7nIYwGLVQg20E7C9zgfA568laQALBAgfbygkuLDfgvgCXikONus6rn0Shuh6qZT1WUodBPU-qg0vUtOV_Ppi1FOx12rx-bbX1SP_2fC98idAbzS_d7a7pMbtnxAtg-H9PxD8tPTJdO6Z5EFjdPKUbCEs8LQpl1WZyC8-Ar2U9VVgWetYag1NrcNBUMvFgOFL0qBO8x9FwaKqYWG2vO-Yrc8oUXbUBSr22oJchS7weAR0l_ffxQl3NjmdAEImtZfIEJT0wH8tVWHMr4c2N-Mqraq8ak6jRtRzSMyn775_OpgNPSGGBmWgFVlWQ7YUeAZisQxMcmdEIq5XNlMhRpCrs2ZpzM0jimAUZhPFFozh4lUAUDlMdkqq9LuEGrTMORKi1gonhhttYhCM9GKmzRTGbcB4SszkGYgTsf-HQv5xwcUaEaiZrCtp5BeM_I8IOFasu7JQ64hswOWJtUJ-Hg5_xRhZhkxc8TigOyuzE8OnqaR4EEz5MjnAdlb_wsuApXTv168PKDULLx6RJJGgocRjKBXjOBxzDjC2YA86Q3_YkYizJBXMSCpN99rT1Xuz2b46-m_Cu6R7Q-vp3L29uj9Lrnd5_mwkPoZ2WqXnX0OcLHVL7wf-A0OKlzG |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Early+production+of+thymic+stromal+lymphopoietin+precedes+infiltration+of+dendritic+cells+expressing+its+receptor+in+allergen-induced+late+phase+cutaneous+responses+in+atopic+subjects&rft.jtitle=Allergy+%28Copenhagen%29&rft.au=Corrigan%2C+C+J&rft.au=Jayaratnam%2C+A&rft.au=Wang%2C+Y&rft.au=Liu%2C+Y&rft.date=2009-07-01&rft.issn=0105-4538&rft.eissn=1398-9995&rft.volume=64&rft.issue=7&rft.spage=1014&rft.epage=1022&rft_id=info:doi/10.1111%2Fj.1398-9995.2009.01947.x&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0105-4538&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0105-4538&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0105-4538&client=summon |