Phosphorylation alters Bim‐mediated Mcl‐1 stabilization and priming - Conage‐Pough, Jason E.; Boise, Lawrence H. (The FEBS journal, 2018)
Keywords: Antineoplastic Agents - pharmacology; Apoptosis; Apoptosis - drug effects; Apoptosis - genetics; Bcl-2-Like Protein 11 - genetics; Bcl-2-Like Protein 11 - metabolism; bcl-X Protein - genetics; bcl-X Protein - metabolism; Bim phosphorylation; Binding; Bortezomib - pharmacology; Cell Line, Tumor; Dependence; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Mcl‐1 stability; Mutation; Myeloid Cell Leukemia Sequence 1 Protein - genetics; Myeloid Cell Leukemia Sequence 1 Protein - metabolism; Myeloid Cells - drug effects; Myeloid Cells - metabolism; Myeloid Cells - pathology; Phosphorylation; Phosphorylation - drug effects; Plasma Cells - drug effects; Plasma Cells - metabolism; Plasma Cells - pathology; Priming; Protein Binding; Protein Processing, Post-Translational; Protein Stability; Proteins; Proto-Oncogene Proteins c-bcl-2 - genetics; Proto-Oncogene Proteins c-bcl-2 - metabolism; Signal Transduction; Stability; priming; Bim phosphorylation; Mcl-1 stability