Mouse Genome Database: From sequence to phenotypes and disease models

Summary The Mouse Genome Database (MGD, www.informatics.jax.org) is the international scientific database for genetic, genomic, and biological data on the laboratory mouse to support the research requirements of the biomedical community. To accomplish this goal, MGD provides broad data coverage, ser...

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Published inGenesis (New York, N.Y. : 2000) Vol. 53; no. 8; pp. 458 - 473
Main Authors Eppig, Janan T., Richardson, Joel E., Kadin, James A., Smith, Cynthia L., Blake, Judith A., Bult, Carol J.
Format Journal Article
LanguageEnglish
Published United States Blackwell Publishing Ltd 01.08.2015
Wiley Subscription Services, Inc
John Wiley and Sons Inc
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Abstract Summary The Mouse Genome Database (MGD, www.informatics.jax.org) is the international scientific database for genetic, genomic, and biological data on the laboratory mouse to support the research requirements of the biomedical community. To accomplish this goal, MGD provides broad data coverage, serves as the authoritative standard for mouse nomenclature for genes, mutants, and strains, and curates and integrates many types of data from literature and electronic sources. Among the key data sets MGD supports are: the complete catalog of mouse genes and genome features, comparative homology data for mouse and vertebrate genes, the authoritative set of Gene Ontology (GO) annotations for mouse gene functions, a comprehensive catalog of mouse mutations and their phenotypes, and a curated compendium of mouse models of human diseases. Here, we describe the data acquisition process, specifics about MGD's key data areas, methods to access and query MGD data, and outreach and user help facilities. genesis 53:458–473, 2015. © 2015 The Authors. Genesis Published by Wiley Periodicals, Inc.
AbstractList The Mouse Genome Database (MGD, www.informatics.jax.org ) is the international scientific database for genetic, genomic, and biological data on the laboratory mouse to support the research requirements of the biomedical community. To accomplish this goal, MGD provides broad data coverage, serves as the authoritative standard for mouse nomenclature for genes, mutants, and strains, and curates and integrates many types of data from literature and electronic sources. Among the key data sets MGD supports are: the complete catalog of mouse genes and genome features, comparative homology data for mouse and vertebrate genes, the authoritative set of Gene Ontology (GO) annotations for mouse gene functions, a comprehensive catalog of mouse mutations and their phenotypes, and a curated compendium of mouse models of human diseases. Here, we describe the data acquisition process, specifics about MGD's key data areas, methods to access and query MGD data, and outreach and user help facilities. genesis 53:458-473, 2015.
Summary The Mouse Genome Database (MGD, www.informatics.jax.org) is the international scientific database for genetic, genomic, and biological data on the laboratory mouse to support the research requirements of the biomedical community. To accomplish this goal, MGD provides broad data coverage, serves as the authoritative standard for mouse nomenclature for genes, mutants, and strains, and curates and integrates many types of data from literature and electronic sources. Among the key data sets MGD supports are: the complete catalog of mouse genes and genome features, comparative homology data for mouse and vertebrate genes, the authoritative set of Gene Ontology (GO) annotations for mouse gene functions, a comprehensive catalog of mouse mutations and their phenotypes, and a curated compendium of mouse models of human diseases. Here, we describe the data acquisition process, specifics about MGD's key data areas, methods to access and query MGD data, and outreach and user help facilities. genesis 53:458-473, 2015. © 2015 The Authors. Genesis Published by Wiley Periodicals, Inc.
The Mouse Genome Database (MGD, www.informatics.jax.org) is the international scientific database for genetic, genomic, and biological data on the laboratory mouse to support the research requirements of the biomedical community. To accomplish this goal, MGD provides broad data coverage, serves as the authoritative standard for mouse nomenclature for genes, mutants, and strains, and curates and integrates many types of data from literature and electronic sources. Among the key data sets MGD supports are: the complete catalog of mouse genes and genome features, comparative homology data for mouse and vertebrate genes, the authoritative set of Gene Ontology (GO) annotations for mouse gene functions, a comprehensive catalog of mouse mutations and their phenotypes, and a curated compendium of mouse models of human diseases. Here, we describe the data acquisition process, specifics about MGD's key data areas, methods to access and query MGD data, and outreach and user help facilities.
The Mouse Genome Database (MGD, www.informatics.jax.org ) is the international scientific database for genetic, genomic, and biological data on the laboratory mouse to support the research requirements of the biomedical community. To accomplish this goal, MGD provides broad data coverage, serves as the authoritative standard for mouse nomenclature for genes, mutants, and strains, and curates and integrates many types of data from literature and electronic sources. Among the key data sets MGD supports are: the complete catalog of mouse genes and genome features, comparative homology data for mouse and vertebrate genes, the authoritative set of Gene Ontology (GO) annotations for mouse gene functions, a comprehensive catalog of mouse mutations and their phenotypes, and a curated compendium of mouse models of human diseases. Here, we describe the data acquisition process, specifics about MGD's key data areas, methods to access and query MGD data, and outreach and user help facilities. genesis 53:458–473, 2015. © 2015 The Authors. Genesis Published by Wiley Periodicals, Inc.
Summary The Mouse Genome Database (MGD, www.informatics.jax.org) is the international scientific database for genetic, genomic, and biological data on the laboratory mouse to support the research requirements of the biomedical community. To accomplish this goal, MGD provides broad data coverage, serves as the authoritative standard for mouse nomenclature for genes, mutants, and strains, and curates and integrates many types of data from literature and electronic sources. Among the key data sets MGD supports are: the complete catalog of mouse genes and genome features, comparative homology data for mouse and vertebrate genes, the authoritative set of Gene Ontology (GO) annotations for mouse gene functions, a comprehensive catalog of mouse mutations and their phenotypes, and a curated compendium of mouse models of human diseases. Here, we describe the data acquisition process, specifics about MGD's key data areas, methods to access and query MGD data, and outreach and user help facilities. genesis 53:458–473, 2015. © 2015 The Authors. Genesis Published by Wiley Periodicals, Inc.
Author Blake, Judith A.
Richardson, Joel E.
Smith, Cynthia L.
Eppig, Janan T.
Bult, Carol J.
Kadin, James A.
AuthorAffiliation 1 The Jackson Laboratory Bar Harbor Maine
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Issue 8
Keywords mouse
genomics
database
gene function
human disease models
Language English
License Attribution
2015 The Authors. Genesis Published by Wiley Periodicals, Inc.
http://creativecommons.org/licenses/by/4.0
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
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Members of the MGD Team: Anna Anagnostopoulos, Richard M. Baldarelli, Jonathan S. Beal, Susan M. Bello, Joanne Berghout, Olin Blodgett, Nancy Butler, Jeffrey W. Campbell, Lori E. Corbani, Howard Dene, Harold J. Drabkin, Kim L. Forthofer, Peter Frost, Sharon C. Giannatto, Paul Hale, Lucie Hutchins, Michelle Knowlton, MeiYee Law, Jill R. Lewis, Monica McAndrews, David B. Miers, Howie Motenko, Li Ni, Hiroaki Onda, Janice E. Ormsby, Wendy Pitman, Jill M. Recla, Beverly Richards‐Smith, David R. Shaw, Dmitry Sitnikov, Kevin R. Stone, Monika Tomcuk, Linda L. Washburn, Yunxia Zhu
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Snippet Summary The Mouse Genome Database (MGD, www.informatics.jax.org) is the international scientific database for genetic, genomic, and biological data on the...
The Mouse Genome Database (MGD, www.informatics.jax.org) is the international scientific database for genetic, genomic, and biological data on the laboratory...
The Mouse Genome Database (MGD, www.informatics.jax.org ) is the international scientific database for genetic, genomic, and biological data on the laboratory...
Summary The Mouse Genome Database (MGD, www.informatics.jax.org) is the international scientific database for genetic, genomic, and biological data on the...
The Mouse Genome Database (MGD, www.informatics.jax.org ) is the international scientific database for genetic, genomic, and biological data on the laboratory...
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wiley
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SubjectTerms Animals
Databases, Genetic
Disease Models, Animal
gene function
Genetic Association Studies
Genome
genomics
Genomics - methods
human disease models
Internet
Mice - genetics
Models, Animal
mouse
Review
Reviews
Sequence Analysis, DNA
Title Mouse Genome Database: From sequence to phenotypes and disease models
URI https://api.istex.fr/ark:/67375/WNG-3KM7Z5LH-R/fulltext.pdf
https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fdvg.22874
https://www.ncbi.nlm.nih.gov/pubmed/26150326
https://www.proquest.com/docview/1705411725
https://search.proquest.com/docview/1712563040
https://pubmed.ncbi.nlm.nih.gov/PMC4545690
Volume 53
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