A guide to plasma membrane solute carrier proteins

• Published in: The FEBS journal Vol. 288; no. 9; pp. 2784 - 2835
• Main Authors: Pizzagalli, Mattia D., Bensimon, Ariel, Superti‐Furga, Giulio
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.05.2021; John Wiley and Sons Inc
• Subjects: A Guide To; amino acids; Cancer; Cell membranes; Cell surface; cellular metabolism; cellular transport; Environmental conditions; Environmental regulations; glucose; humans; Metabolism; Organelles; physiology; plasma membrane; Protein transport; Proteins; Reviews; solute carrier transporter; solutes; glucose; plasma membrane; cellular transport; amino acids; cellular metabolism; solute carrier transporter; cell surface; pH; physiology; cancer

This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily of transporter proteins and their roles in human cells. The SLC superfamily currently includes 458 transport proteins in 65 families that carry a wide variety of substances across cellular membranes. While...