Deleterious- and Disease-Allele Prevalence in Healthy Individuals: Insights from Current Predictions, Mutation Databases, and Population-Scale Resequencing - Xue, Yali; Chen, Yuan; Ayub, Qasim; Huang, Ni; Ball, Edward V.; Mort, Matthew; Phillips, Andrew D.; Shaw, Katy; Stenson, Peter D.; Cooper, David N.; Tyler-Smith, Chris (American journal of human genetics, 2012)
Keywords: Alleles; Biological and medical sciences; Databases, Nucleic Acid; Fundamental and applied biological sciences. Psychology; Genetic disorders; Genetics of eukaryotes. Biological and molecular evolution; Genome, Human; Genome-Wide Association Study; Human Genome Project; Humans; Medical genetics; Medical sciences; Molecular and cellular biology; Mutation; Mutation Rate; Mutation, Missense; Polymorphism; Prevalence; Human; Allele; Prevalence; Disease; Evaluation scale; Prediction; Database; Genetics; Population; Mutation; Predictive factor; Public health