Effects of mental health interventions among people hospitalized with COVID-19 infection: A systematic review of randomized controlled trials
We evaluated the effects of mental health interventions among people hospitalized with COVID-19. We conducted a systematic review and searched 9 databases (2 Chinese-language) from December 31, 2019 to June 28, 2021. Eligible randomized controlled trials assessed interventions among hospitalized COV...
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| Published in | General hospital psychiatry Vol. 77; pp. 40 - 68 |
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| Main Authors | , , , , , , , , , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Elsevier Inc
01.07.2022
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| Subjects | |
| Online Access | Get full text |
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| Abstract | We evaluated the effects of mental health interventions among people hospitalized with COVID-19.
We conducted a systematic review and searched 9 databases (2 Chinese-language) from December 31, 2019 to June 28, 2021. Eligible randomized controlled trials assessed interventions among hospitalized COVID-19 patients that targeted mental health symptoms. Due to the poor quality of trials, we sought to verify accuracy of trial reports including results.
We identified 47 randomized controlled trials from China (N = 42), Iran (N = 4) and Turkey (N = 1) of which 21 tested the efficacy of psychological interventions, 5 physical and breathing exercises, and 21 a combination of interventions. Trial information could only be verified for 3 trials of psychological interventions (cognitive behavioral, guided imagery, multicomponent online), and these were the only trials with low risk of bias on at least 4 of 7 domains. Results could not be pooled or interpreted with confidence due to the degree of poor reporting and trial quality, the frequency of what were deemed implausibly large effects, and heterogeneity.
Trials of interventions to address mental health in hospitalized COVID-19 patients, collectively, are not of sufficient quality to inform practice. Health care providers should refer to existing expert recommendations and standard hospital-based practices.
Registration: PROSPERO (CRD42020179703); registered on April 17, 2020. |
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| AbstractList | We evaluated the effects of mental health interventions among people hospitalized with COVID-19.
We conducted a systematic review and searched 9 databases (2 Chinese-language) from December 31, 2019 to June 28, 2021. Eligible randomized controlled trials assessed interventions among hospitalized COVID-19 patients that targeted mental health symptoms. Due to the poor quality of trials, we sought to verify accuracy of trial reports including results.
We identified 47 randomized controlled trials from China (N = 42), Iran (N = 4) and Turkey (N = 1) of which 21 tested the efficacy of psychological interventions, 5 physical and breathing exercises, and 21 a combination of interventions. Trial information could only be verified for 3 trials of psychological interventions (cognitive behavioral, guided imagery, multicomponent online), and these were the only trials with low risk of bias on at least 4 of 7 domains. Results could not be pooled or interpreted with confidence due to the degree of poor reporting and trial quality, the frequency of what were deemed implausibly large effects, and heterogeneity.
Trials of interventions to address mental health in hospitalized COVID-19 patients, collectively, are not of sufficient quality to inform practice. Health care providers should refer to existing expert recommendations and standard hospital-based practices.
PROSPERO (CRD42020179703); registered on April 17, 2020. We evaluated the effects of mental health interventions among people hospitalized with COVID-19. We conducted a systematic review and searched 9 databases (2 Chinese-language) from December 31, 2019 to June 28, 2021. Eligible randomized controlled trials assessed interventions among hospitalized COVID-19 patients that targeted mental health symptoms. Due to the poor quality of trials, we sought to verify accuracy of trial reports including results. We identified 47 randomized controlled trials from China (N = 42), Iran (N = 4) and Turkey (N = 1) of which 21 tested the efficacy of psychological interventions, 5 physical and breathing exercises, and 21 a combination of interventions. Trial information could only be verified for 3 trials of psychological interventions (cognitive behavioral, guided imagery, multicomponent online), and these were the only trials with low risk of bias on at least 4 of 7 domains. Results could not be pooled or interpreted with confidence due to the degree of poor reporting and trial quality, the frequency of what were deemed implausibly large effects, and heterogeneity. Trials of interventions to address mental health in hospitalized COVID-19 patients, collectively, are not of sufficient quality to inform practice. Health care providers should refer to existing expert recommendations and standard hospital-based practices. Registration: PROSPERO (CRD42020179703); registered on April 17, 2020. We evaluated the effects of mental health interventions among people hospitalized with COVID-19.OBJECTIVEWe evaluated the effects of mental health interventions among people hospitalized with COVID-19.We conducted a systematic review and searched 9 databases (2 Chinese-language) from December 31, 2019 to June 28, 2021. Eligible randomized controlled trials assessed interventions among hospitalized COVID-19 patients that targeted mental health symptoms. Due to the poor quality of trials, we sought to verify accuracy of trial reports including results.METHODSWe conducted a systematic review and searched 9 databases (2 Chinese-language) from December 31, 2019 to June 28, 2021. Eligible randomized controlled trials assessed interventions among hospitalized COVID-19 patients that targeted mental health symptoms. Due to the poor quality of trials, we sought to verify accuracy of trial reports including results.We identified 47 randomized controlled trials from China (N = 42), Iran (N = 4) and Turkey (N = 1) of which 21 tested the efficacy of psychological interventions, 5 physical and breathing exercises, and 21 a combination of interventions. Trial information could only be verified for 3 trials of psychological interventions (cognitive behavioral, guided imagery, multicomponent online), and these were the only trials with low risk of bias on at least 4 of 7 domains. Results could not be pooled or interpreted with confidence due to the degree of poor reporting and trial quality, the frequency of what were deemed implausibly large effects, and heterogeneity.RESULTSWe identified 47 randomized controlled trials from China (N = 42), Iran (N = 4) and Turkey (N = 1) of which 21 tested the efficacy of psychological interventions, 5 physical and breathing exercises, and 21 a combination of interventions. Trial information could only be verified for 3 trials of psychological interventions (cognitive behavioral, guided imagery, multicomponent online), and these were the only trials with low risk of bias on at least 4 of 7 domains. Results could not be pooled or interpreted with confidence due to the degree of poor reporting and trial quality, the frequency of what were deemed implausibly large effects, and heterogeneity.Trials of interventions to address mental health in hospitalized COVID-19 patients, collectively, are not of sufficient quality to inform practice. Health care providers should refer to existing expert recommendations and standard hospital-based practices.CONCLUSIONTrials of interventions to address mental health in hospitalized COVID-19 patients, collectively, are not of sufficient quality to inform practice. Health care providers should refer to existing expert recommendations and standard hospital-based practices.PROSPERO (CRD42020179703); registered on April 17, 2020.REGISTRATIONPROSPERO (CRD42020179703); registered on April 17, 2020. |
| Author | Sun, Ying Fahim, Christine Agic, Branka Dal Santo, Tiffany Thombs, Brett D. Jiang, Xiaowen Wu, Yin Martin, Michael S. Markham, Sarah Rice, Danielle B. Li, Letong Sockalingam, Sanjeev Thombs-Vite, Ian Krishnan, Ankur Bonardi, Olivia Fan, Suiqiong Tasleem, Amina Wang, Yutong Li, Kexin Benedetti, Andrea Boruff, Jill T. He, Chen |
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| Cites_doi | 10.1136/bmj.323.7303.42 10.1136/bmj.d5928 10.1136/bmj.c869 10.1080/13548506.2021.1916956 10.1038/s41591-021-01292-y 10.1016/j.jclinepi.2014.11.023 10.1016/S2213-2600(20)30161-2 10.1177/07067437211070648 10.2196/26883 10.1016/j.jpsychores.2020.110113 10.1001/jama.2020.19719 10.1097/CCM.0000000000003974 10.1111/ppc.12750 10.4103/jfmpc.jfmpc_847_20 10.1016/j.jclinepi.2010.07.015 10.1016/j.jclinepi.2020.04.025 10.1016/j.jclinepi.2017.08.010 10.1016/j.ctcp.2020.101132 10.1136/bmj.g1687 10.1631/jzus.B2010013 10.1001/jama.2018.17824 10.1186/s12888-021-03085-6 10.1016/j.ctcp.2021.101335 10.1001/jamainternmed.2018.8009 |
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| Keywords | COVID-19 Interventions CI Mental health Systematic review ICU TIDieR SMD Randomized controlled trials |
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| Title | Effects of mental health interventions among people hospitalized with COVID-19 infection: A systematic review of randomized controlled trials |
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