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Keywords: 631/1647/2210/2213; 692/699/67/589/466; 692/700/139; Antigens; Biomarkers, Tumor - genetics; Biomedical and Life Sciences; Biomedicine; Biopsy; Body fluids; Body Fluids - chemistry; Cancer Research; Case-Control Studies; Clinical Study; DNA Methylation; DNA Primers; DNA, Neoplasm - genetics; Drug Resistance; Epidemiology; Genomes; Glutathione S-Transferase pi - genetics; Humans; Male; Medical diagnosis; Medical research; Meta-analysis; Molecular Medicine; Oncology; Plasma; Polymerase Chain Reaction; Promoter Regions, Genetic - genetics; Prostate - metabolism; Prostate cancer; Prostate-Specific Antigen - genetics; Prostatic Neoplasms - diagnosis; Prostatic Neoplasms - genetics; Sensitivity and Specificity; Urine; United States--US; molecular epidemiology; methylation sensitive restriction endonuclease-qPCR; quantitative methylation test; prostate cancer diagnosis; methylated and unmethylated sequence; serial testing, primer sequence