The importance of combining serological testing with RT-PCR assays for efficient detection of COVID-19 and higher diagnostic accuracy

• Published in: PeerJ (San Francisco, CA) Vol. 11; p. e15024
• Main Authors: Alamri, Sawsan S., Alsaieedi, Ahdab, Khouqeer, Yousef, Afeef, Marwah, Alharbi, Samiyah, Algaissi, Abdullah, Alghanmi, Maimonah, Altorki, Tarfa, Zawawi, Ayat, Alfaleh, Mohamed A., Hashem, Anwar M., Alhabbab, Rowa
• Format: Journal Article
• Language: English
• Published: United States PeerJ. Ltd 11.04.2023; PeerJ Inc
• Subjects: COVID-19; COVID-19 - diagnosis; COVID-19 Testing; Diagnostic; Enzyme-linked immunosorbent assay; Epidemiology; Health aspects; Humans; Immunoglobulin G; Immunoglobulin G - analysis; Immunoglobulin M - analysis; Infection; Infectious Diseases; Medical personnel; Medical research; Medicine, Experimental; Reverse Transcriptase Polymerase Chain Reaction; SARS-CoV-2; SARS-CoV-2 - genetics; Serology; Testing profile; Saudi Arabia; COVID-19; Infection; Healthcare worker; SARS-CoV-2; RT-PCR; Diagnostic; Serology; Testing profile

Misdiagnosing suspected COVID-19 individuals could largely contribute to the viruses transmission, therefore, making an accurate diagnosis of infected subjects vital in minimizing and containing the disease. Although RT-PCR is the standard method in detecting COVID-19, it is associated with some lim...