Reduced mtDNA Copy Number Links to Vascular Calcification and Restores After Transplantation - Schwarz, Angelina; Qureshi, Abdul Rashid; Hernandez, Leah; Wennberg, Lars; Wernerson, Annika; Kublickiene, Karolina; Shiels, Paul G.; Filograna, Roberta; Stenvinkel, Peter; Witasp, Anna (Cells (Basel, Switzerland), 2025)
Keywords: Adult; Age; Aged; Aging; Analysis; Blood pressure; Body mass index; CAC score; Calcification; Calcification (ectopic); Cancer; Cardiovascular diseases; Case-Control Studies; Cholesterol; Chronic kidney failure; CKD; Copy number; Coronary vessels; Development and progression; Diabetes; DNA Copy Number Variations - genetics; DNA, Mitochondrial - genetics; early vascular calcification; Female; Genes; Genetic testing; Health aspects; Hemoglobin; High density lipoprotein; Homeostasis; Humans; Inflammation; Kidney diseases; Kidney Transplantation; Kidneys; Male; Middle Aged; Mitochondria; Mitochondrial DNA; Mortality; mtDNA copy number; Oxidative phosphorylation; Patients; Phosphorylation; Renal Insufficiency, Chronic - genetics; renal transplantation; Senescence; Therapeutic targets; Transplantation; Type 2 diabetes; United States; Vascular Calcification - genetics; Veins & arteries; United States; United States--US; Germany; CAC score; early vascular calcification; CKD; mtDNA copy number; renal transplantation