Novel insights from our special issue on maternal factors during pregnancy that influence maternal, fetal and childhood outcomes

• Published in: BMC medicine Vol. 22; no. 1; p. 79
• Main Authors: Tong, Stephen, Benhalima, Katrien, Muglia, Louis, Ozanne, Susan
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 20.02.2024; BioMed Central; BMC
• Subjects: Adipocytes; Artificial intelligence; Body mass index; Breast feeding; Breastfeeding & lactation; Child; Children; Cohort analysis; Diabetes mellitus; Family; Female; Fetuses; Gestational age; Gestational diabetes; Heart; Humans; Machine learning; Medicine; Mental disorders; Meta-analysis; Metabolic disorders; Metabolic syndrome; Microbiota; Neonates; Offspring; Physiology; Population studies; Pre-eclampsia; Pregnancy; Pregnancy complications; Pregnancy Complications - epidemiology; Premature birth; Proton pump inhibitors; Protons; Reviews; Risk factors; Sepsis; Small for gestational age; Steroids; Vagina; Womens health; Sweden
• DOI: 10.1186/s12916-024-03278-2
• ISSN: 1741-7015

Part of the collection are insightful reviews, including an umbrella review examining risk factors for preterm birth (an adverse outcome that frequently echoes upon the lifelong health of the offspring) [1], a meta-analysis exploring potential links between breastfeeding and mental health conditions in both mother and child [2] and a fascinating narrative review on how in utero fetal programming of the metabolic syndrome may be facilitated through a failure of proper differentiation of fetal adipocytes. Another population-based cohort study from Sweden reported potential harms associated with pregnant women taking proton pump inhibitors (a treatment for gastric reflux symptoms), including increased risks of preeclampsia, gestational diabetes and the birth of a small for gestational age infant [5]. [...]as continuing members of the editorial board, we hope those in our field will keep the manuscripts rolling in. Breddels EM, Simin J, Fornes R, Lilja Engstrand H, Engstrand L, Bruyndonckx R, Brusselaers N. Population-based cohort study: proton pump inhibitor use during pregnancy in Sweden and the risk of maternal and neonatal adverse events.