Retinoic acid receptor alpha gene expression in the rat testis: potential role during the prophase of meiosis and in the transition from round to elongating spermatids

• Published in: Biology of reproduction Vol. 56; no. 2; pp. 549 - 556
• Main Authors: Akmal, K.M. (Washington State University, Pullman, WA.), Dufour, J.M, Kim, K.H
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Madison, WI Society for the Study of Reproduction 01.02.1997
• Subjects: Aging; Animals; ARN MENSAJERO; ARN MESSAGER; Biological and medical sciences; Blotting, Northern; Cell Nucleus - chemistry; CHIMIORECEPTEUR; ESPERMATOGENESIS; ESPERMATOZOO; EXPRESION GENICA; EXPRESSION DES GENES; Fundamental and applied biological sciences. Psychology; GENE; Gene Expression; GENES; Immunohistochemistry; In Situ Hybridization; Male; Mammalian male genital system; MEIOSE; MEIOSIS; Meiosis - physiology; Morphology. Physiology; Prophase - physiology; QUIMIORECEPTORES; RAT; RATA; Rats; Rats, Sprague-Dawley; Receptors, Retinoic Acid - analysis; Receptors, Retinoic Acid - genetics; RETINOL; RNA, Messenger - analysis; Spermatids - cytology; SPERMATOGENESE; Spermatogenesis; SPERMATOZOIDE; TESTICULE; TESTICULOS; Testis - growth & development; Testis - metabolism; Vertebrates: reproduction; Rat; Spermatogenesis; Rodentia; Vitamin; Male; Meiosis; Retinoids; Germinal cell; Gene expression; Testicle; Male genital system; Spermatid; Retinol; Vertebrata; Specificity; Mammalia; Target cell; Cell; Retinoic acid; Biological receptor

Mutational studies have identified retinoic acid receptor (RARalpha) as having an essential role in spermatogenesis. The objective of this study was to determine which cells express RARalpha within the normal rat testis by conducting in situ analyses for mRNA and protein. Characterization of RARalph...