Corneal subbasal nerve plexus reinnervation and stromal cell morphology with different cap thicknesses in small incision lenticule extraction

The corneal cap thickness is a vital parameter designed in small incision lenticule extraction (SMILE). The purpose was to investigate the changes in corneal subbasal nerve plexus (SNP) and stromal cells with different cap thicknesses and evaluate the optimized design for the surgery. In this prospe...

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Published inEye and vision (Novato, Calif.) Vol. 11; no. 1; p. 15
Main Authors Song, Yanzheng, Deng, Shijing, Lyv, Xiaotong, Xu, Yushan, Zhang, Fengju, Guo, Ning
Format Journal Article
LanguageEnglish
Published England BioMed Central Ltd 08.04.2024
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Abstract The corneal cap thickness is a vital parameter designed in small incision lenticule extraction (SMILE). The purpose was to investigate the changes in corneal subbasal nerve plexus (SNP) and stromal cells with different cap thicknesses and evaluate the optimized design for the surgery. In this prospective, comparative, non-randomized study, a total of 108 eyes of 54 patients who underwent SMILE were allocated into three groups with different corneal cap thicknesses (110 μm, 120 μm or 130 μm group). The SNP and stromal cell morphological changes obtained from in vivo corneal confocal microscopy (IVCCM) along with their refractive outcomes were collected at 1 week, 1 month, 3 months and 6 months postoperatively. One-way analysis of variance (ANOVA) was used to compare the parameters among the three groups. The SNPs in the three groups all decreased after surgery and revealed a gradual increasing trend during the 6-month follow-up. The values of the quantitative nerve metrics were significantly lower in the 110 μm group than in the 120 μm and 130 μm groups, especially at 1 week postoperatively. No difference was detected between the 120 μm and 130 μm groups at any time point. Both Langerhans cells and keratocytes were activated after surgery, and the activation was alleviated during the follow-up. The SMILE surgeries with 110 μm, 120 μm or 130 μm cap thickness design achieved good efficacy, safety, accuracy and stability for moderate to high myopic correction while the thicker corneal cap was more beneficial for corneal nerve regeneration.
AbstractList PurposeThe corneal cap thickness is a vital parameter designed in small incision lenticule extraction (SMILE). The purpose was to investigate the changes in corneal subbasal nerve plexus (SNP) and stromal cells with different cap thicknesses and evaluate the optimized design for the surgery.MethodsIn this prospective, comparative, non-randomized study, a total of 108 eyes of 54 patients who underwent SMILE were allocated into three groups with different corneal cap thicknesses (110 μm, 120 μm or 130 μm group). The SNP and stromal cell morphological changes obtained from in vivo corneal confocal microscopy (IVCCM) along with their refractive outcomes were collected at 1 week, 1 month, 3 months and 6 months postoperatively. One-way analysis of variance (ANOVA) was used to compare the parameters among the three groups.ResultsThe SNPs in the three groups all decreased after surgery and revealed a gradual increasing trend during the 6-month follow-up. The values of the quantitative nerve metrics were significantly lower in the 110 μm group than in the 120 μm and 130 μm groups, especially at 1 week postoperatively. No difference was detected between the 120 μm and 130 μm groups at any time point. Both Langerhans cells and keratocytes were activated after surgery, and the activation was alleviated during the follow-up.ConclusionsThe SMILE surgeries with 110 μm, 120 μm or 130 μm cap thickness design achieved good efficacy, safety, accuracy and stability for moderate to high myopic correction while the thicker corneal cap was more beneficial for corneal nerve regeneration.
Abstract Purpose The corneal cap thickness is a vital parameter designed in small incision lenticule extraction (SMILE). The purpose was to investigate the changes in corneal subbasal nerve plexus (SNP) and stromal cells with different cap thicknesses and evaluate the optimized design for the surgery. Methods In this prospective, comparative, non-randomized study, a total of 108 eyes of 54 patients who underwent SMILE were allocated into three groups with different corneal cap thicknesses (110 μm, 120 μm or 130 μm group). The SNP and stromal cell morphological changes obtained from in vivo corneal confocal microscopy (IVCCM) along with their refractive outcomes were collected at 1 week, 1 month, 3 months and 6 months postoperatively. One-way analysis of variance (ANOVA) was used to compare the parameters among the three groups. Results The SNPs in the three groups all decreased after surgery and revealed a gradual increasing trend during the 6-month follow-up. The values of the quantitative nerve metrics were significantly lower in the 110 μm group than in the 120 μm and 130 μm groups, especially at 1 week postoperatively. No difference was detected between the 120 μm and 130 μm groups at any time point. Both Langerhans cells and keratocytes were activated after surgery, and the activation was alleviated during the follow-up. Conclusions The SMILE surgeries with 110 μm, 120 μm or 130 μm cap thickness design achieved good efficacy, safety, accuracy and stability for moderate to high myopic correction while the thicker corneal cap was more beneficial for corneal nerve regeneration.
The corneal cap thickness is a vital parameter designed in small incision lenticule extraction (SMILE). The purpose was to investigate the changes in corneal subbasal nerve plexus (SNP) and stromal cells with different cap thicknesses and evaluate the optimized design for the surgery. In this prospective, comparative, non-randomized study, a total of 108 eyes of 54 patients who underwent SMILE were allocated into three groups with different corneal cap thicknesses (110 μm, 120 μm or 130 μm group). The SNP and stromal cell morphological changes obtained from in vivo corneal confocal microscopy (IVCCM) along with their refractive outcomes were collected at 1 week, 1 month, 3 months and 6 months postoperatively. One-way analysis of variance (ANOVA) was used to compare the parameters among the three groups. The SNPs in the three groups all decreased after surgery and revealed a gradual increasing trend during the 6-month follow-up. The values of the quantitative nerve metrics were significantly lower in the 110 μm group than in the 120 μm and 130 μm groups, especially at 1 week postoperatively. No difference was detected between the 120 μm and 130 μm groups at any time point. Both Langerhans cells and keratocytes were activated after surgery, and the activation was alleviated during the follow-up. The SMILE surgeries with 110 μm, 120 μm or 130 μm cap thickness design achieved good efficacy, safety, accuracy and stability for moderate to high myopic correction while the thicker corneal cap was more beneficial for corneal nerve regeneration.
Purpose The corneal cap thickness is a vital parameter designed in small incision lenticule extraction (SMILE). The purpose was to investigate the changes in corneal subbasal nerve plexus (SNP) and stromal cells with different cap thicknesses and evaluate the optimized design for the surgery. Methods In this prospective, comparative, non-randomized study, a total of 108 eyes of 54 patients who underwent SMILE were allocated into three groups with different corneal cap thicknesses (110 [mu]m, 120 [mu]m or 130 [mu]m group). The SNP and stromal cell morphological changes obtained from in vivo corneal confocal microscopy (IVCCM) along with their refractive outcomes were collected at 1 week, 1 month, 3 months and 6 months postoperatively. One-way analysis of variance (ANOVA) was used to compare the parameters among the three groups. Results The SNPs in the three groups all decreased after surgery and revealed a gradual increasing trend during the 6-month follow-up. The values of the quantitative nerve metrics were significantly lower in the 110 [mu]m group than in the 120 [mu]m and 130 [mu]m groups, especially at 1 week postoperatively. No difference was detected between the 120 [mu]m and 130 [mu]m groups at any time point. Both Langerhans cells and keratocytes were activated after surgery, and the activation was alleviated during the follow-up. Conclusions The SMILE surgeries with 110 [mu]m, 120 [mu]m or 130 [mu]m cap thickness design achieved good efficacy, safety, accuracy and stability for moderate to high myopic correction while the thicker corneal cap was more beneficial for corneal nerve regeneration. Keywords: ACCMetrics, Automated analysis, Cap thickness, In vivo corneal confocal microscopy, Myopia, Refractive surgery, Small incision lenticule extraction, Subbasal nerve plexus
The corneal cap thickness is a vital parameter designed in small incision lenticule extraction (SMILE). The purpose was to investigate the changes in corneal subbasal nerve plexus (SNP) and stromal cells with different cap thicknesses and evaluate the optimized design for the surgery. In this prospective, comparative, non-randomized study, a total of 108 eyes of 54 patients who underwent SMILE were allocated into three groups with different corneal cap thicknesses (110 [mu]m, 120 [mu]m or 130 [mu]m group). The SNP and stromal cell morphological changes obtained from in vivo corneal confocal microscopy (IVCCM) along with their refractive outcomes were collected at 1 week, 1 month, 3 months and 6 months postoperatively. One-way analysis of variance (ANOVA) was used to compare the parameters among the three groups. The SNPs in the three groups all decreased after surgery and revealed a gradual increasing trend during the 6-month follow-up. The values of the quantitative nerve metrics were significantly lower in the 110 [mu]m group than in the 120 [mu]m and 130 [mu]m groups, especially at 1 week postoperatively. No difference was detected between the 120 [mu]m and 130 [mu]m groups at any time point. Both Langerhans cells and keratocytes were activated after surgery, and the activation was alleviated during the follow-up. The SMILE surgeries with 110 [mu]m, 120 [mu]m or 130 [mu]m cap thickness design achieved good efficacy, safety, accuracy and stability for moderate to high myopic correction while the thicker corneal cap was more beneficial for corneal nerve regeneration.
ArticleNumber 15
Audience Academic
Author Zhang, Fengju
Xu, Yushan
Deng, Shijing
Song, Yanzheng
Lyv, Xiaotong
Guo, Ning
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Cites_doi 10.1167/iovs.62.6.5
10.3928/1081597X-20160512-01
10.1159/000520241
10.3928/1081597X-20191216-01
10.1007/s00417-013-2400-x
10.1167/iovs.18-24516
10.1167/iovs.17-23342
10.1097/APO.0000000000000259
10.1097/ICO.0000000000002312
10.3390/jcm11092611
10.1097/ICO.0000000000000924
10.1186/s12886-023-02786-8
10.1080/08820538.2020.1807028
10.1371/journal.pone.0081435
10.3928/1081597X-20190205-01
10.1097/OPX.0000000000001484
10.1097/ICO.0000000000000571
10.1080/02713683.2019.1600196
10.1007/s10792-020-01362-z
10.1038/srep29802
10.1016/j.ophtha.2014.11.006
10.1097/ICO.0000000000002549
10.1007/s00417-018-04225-7
10.1016/j.jtos.2016.09.004
10.1167/iovs.11-8786
10.1097/ICO.0000000000003294
10.3928/1081597X-20141218-01
10.1371/journal.pone.0163259
10.1007/s10792-021-01821-1
10.3928/1081597X-20150820-02
10.1212/WNL.0000000000206902
10.1097/ICO.0000000000001835
10.1212/WNL.0000000000004033
10.1167/iovs.17-23675
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Issue 1
Keywords Subbasal nerve plexus
In vivo corneal confocal microscopy
Small incision lenticule extraction
Myopia
Refractive surgery
Automated analysis
ACCMetrics
Cap thickness
Language English
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References AA Ahmed (381_CR1) 2020; 35
M Liu (381_CR11) 2016; 35
JS Takhar (381_CR20) 2021; 40
A Kheirkhah (381_CR4) 2015; 122
AH Vestergaard (381_CR27) 2013; 251
J Siedlecki (381_CR35) 2019; 8
LH Colorado (381_CR24) 2019; 44
S Ganesh (381_CR32) 2016; 32
D Wu (381_CR9) 2020; 36
LH Colorado (381_CR17) 2022; 11
EA Deák (381_CR18) 2019; 60
EJH Lewis (381_CR19) 2017; 88
S Ganesh (381_CR7) 2021; 41
A Recchioni (381_CR5) 2020; 39
H Lee (381_CR14) 2019; 35
AA El-Massry (381_CR10) 2015; 34
X Chen (381_CR22) 2018; 59
YC Liu (381_CR25) 2016; 6
IB Damgaard (381_CR30) 2018; 59
G Giannaccare (381_CR21) 2019; 257
M He (381_CR6) 2016; 11
L D'Onofrio (381_CR23) 2021; 62
R Ishii (381_CR26) 2015; 31
T Liu (381_CR29) 2018; 2018
F Zhang (381_CR28) 2012; 53
M Markoulli (381_CR3) 2020; 97
X Lv (381_CR15) 2023; 23
C Liang (381_CR34) 2022; 65
M Li (381_CR16) 2013; 8
F Wu (381_CR8) 2019; 38
W Yang (381_CR12) 2020; 40
JL Güell (381_CR31) 2015; 31
A Cruzat (381_CR2) 2017; 15
S Zarei-Ghanavati (381_CR33) 2024; 43
SS Gylfadottir (381_CR13) 2023; 100
References_xml – volume: 62
  start-page: 5
  issue: 6
  year: 2021
  ident: 381_CR23
  publication-title: Invest Ophthalmol Vis Sci
  doi: 10.1167/iovs.62.6.5
  contributor:
    fullname: L D'Onofrio
– volume: 32
  start-page: 473
  issue: 7
  year: 2016
  ident: 381_CR32
  publication-title: J Refract Surg
  doi: 10.3928/1081597X-20160512-01
  contributor:
    fullname: S Ganesh
– volume: 65
  start-page: 4
  issue: 1
  year: 2022
  ident: 381_CR34
  publication-title: Ophthalmic Res
  doi: 10.1159/000520241
  contributor:
    fullname: C Liang
– volume: 36
  start-page: 82
  issue: 2
  year: 2020
  ident: 381_CR9
  publication-title: J Refract Surg
  doi: 10.3928/1081597X-20191216-01
  contributor:
    fullname: D Wu
– volume: 251
  start-page: 2591
  issue: 11
  year: 2013
  ident: 381_CR27
  publication-title: Graefes Arch Clin Exp Ophthalmol
  doi: 10.1007/s00417-013-2400-x
  contributor:
    fullname: AH Vestergaard
– volume: 60
  start-page: 830
  issue: 2
  year: 2019
  ident: 381_CR18
  publication-title: Invest Ophthalmol Vis Sci
  doi: 10.1167/iovs.18-24516
  contributor:
    fullname: EA Deák
– volume: 59
  start-page: 1113
  issue: 2
  year: 2018
  ident: 381_CR22
  publication-title: Invest Ophthalmol Vis Sci
  doi: 10.1167/iovs.17-23342
  contributor:
    fullname: X Chen
– volume: 8
  start-page: 406
  issue: 5
  year: 2019
  ident: 381_CR35
  publication-title: Asia Pac J Ophthalmol
  doi: 10.1097/APO.0000000000000259
  contributor:
    fullname: J Siedlecki
– volume: 39
  start-page: 851
  issue: 7
  year: 2020
  ident: 381_CR5
  publication-title: Cornea
  doi: 10.1097/ICO.0000000000002312
  contributor:
    fullname: A Recchioni
– volume: 11
  start-page: 2611
  issue: 9
  year: 2022
  ident: 381_CR17
  publication-title: J Clin Med
  doi: 10.3390/jcm11092611
  contributor:
    fullname: LH Colorado
– volume: 35
  start-page: 1308
  issue: 10
  year: 2016
  ident: 381_CR11
  publication-title: Cornea
  doi: 10.1097/ICO.0000000000000924
  contributor:
    fullname: M Liu
– volume: 23
  start-page: 42
  issue: 1
  year: 2023
  ident: 381_CR15
  publication-title: BMC Ophthalmol
  doi: 10.1186/s12886-023-02786-8
  contributor:
    fullname: X Lv
– volume: 2018
  start-page: 6040873
  year: 2018
  ident: 381_CR29
  publication-title: J Ophthalmol
  contributor:
    fullname: T Liu
– volume: 35
  start-page: 224
  issue: 4
  year: 2020
  ident: 381_CR1
  publication-title: Semin Ophthalmol
  doi: 10.1080/08820538.2020.1807028
  contributor:
    fullname: AA Ahmed
– volume: 8
  issue: 12
  year: 2013
  ident: 381_CR16
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0081435
  contributor:
    fullname: M Li
– volume: 35
  start-page: 153
  issue: 3
  year: 2019
  ident: 381_CR14
  publication-title: J Refract Surg
  doi: 10.3928/1081597X-20190205-01
  contributor:
    fullname: H Lee
– volume: 97
  start-page: 145
  issue: 3
  year: 2020
  ident: 381_CR3
  publication-title: Optom Vis Sci
  doi: 10.1097/OPX.0000000000001484
  contributor:
    fullname: M Markoulli
– volume: 34
  start-page: 1272
  issue: 10
  year: 2015
  ident: 381_CR10
  publication-title: Cornea
  doi: 10.1097/ICO.0000000000000571
  contributor:
    fullname: AA El-Massry
– volume: 44
  start-page: 840
  issue: 8
  year: 2019
  ident: 381_CR24
  publication-title: Curr Eye Res
  doi: 10.1080/02713683.2019.1600196
  contributor:
    fullname: LH Colorado
– volume: 40
  start-page: 1905
  issue: 8
  year: 2020
  ident: 381_CR12
  publication-title: Int Ophthalmol
  doi: 10.1007/s10792-020-01362-z
  contributor:
    fullname: W Yang
– volume: 6
  start-page: 29802
  year: 2016
  ident: 381_CR25
  publication-title: Sci Rep
  doi: 10.1038/srep29802
  contributor:
    fullname: YC Liu
– volume: 122
  start-page: 662
  issue: 4
  year: 2015
  ident: 381_CR4
  publication-title: Ophthalmology
  doi: 10.1016/j.ophtha.2014.11.006
  contributor:
    fullname: A Kheirkhah
– volume: 40
  start-page: 603
  issue: 5
  year: 2021
  ident: 381_CR20
  publication-title: Cornea
  doi: 10.1097/ICO.0000000000002549
  contributor:
    fullname: JS Takhar
– volume: 257
  start-page: 583
  issue: 3
  year: 2019
  ident: 381_CR21
  publication-title: Graefes Arch Clin Exp Ophthalmol
  doi: 10.1007/s00417-018-04225-7
  contributor:
    fullname: G Giannaccare
– volume: 15
  start-page: 15
  issue: 1
  year: 2017
  ident: 381_CR2
  publication-title: Ocul Surf
  doi: 10.1016/j.jtos.2016.09.004
  contributor:
    fullname: A Cruzat
– volume: 53
  start-page: 5536
  issue: 9
  year: 2012
  ident: 381_CR28
  publication-title: Invest Ophthalmol Vis Sci
  doi: 10.1167/iovs.11-8786
  contributor:
    fullname: F Zhang
– volume: 43
  start-page: 154
  issue: 2
  year: 2024
  ident: 381_CR33
  publication-title: Cornea
  doi: 10.1097/ICO.0000000000003294
  contributor:
    fullname: S Zarei-Ghanavati
– volume: 31
  start-page: 10
  issue: 1
  year: 2015
  ident: 381_CR26
  publication-title: J Refract Surg
  doi: 10.3928/1081597X-20141218-01
  contributor:
    fullname: R Ishii
– volume: 11
  issue: 9
  year: 2016
  ident: 381_CR6
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0163259
  contributor:
    fullname: M He
– volume: 41
  start-page: 2657
  issue: 8
  year: 2021
  ident: 381_CR7
  publication-title: Int Ophthalmol
  doi: 10.1007/s10792-021-01821-1
  contributor:
    fullname: S Ganesh
– volume: 31
  start-page: 580
  issue: 9
  year: 2015
  ident: 381_CR31
  publication-title: J Refract Surg
  doi: 10.3928/1081597X-20150820-02
  contributor:
    fullname: JL Güell
– volume: 100
  start-page: e1680
  issue: 16
  year: 2023
  ident: 381_CR13
  publication-title: Neurology
  doi: 10.1212/WNL.0000000000206902
  contributor:
    fullname: SS Gylfadottir
– volume: 38
  start-page: 617
  issue: 5
  year: 2019
  ident: 381_CR8
  publication-title: Cornea
  doi: 10.1097/ICO.0000000000001835
  contributor:
    fullname: F Wu
– volume: 88
  start-page: 2294
  issue: 24
  year: 2017
  ident: 381_CR19
  publication-title: Neurology
  doi: 10.1212/WNL.0000000000004033
  contributor:
    fullname: EJH Lewis
– volume: 59
  start-page: 1836
  issue: 5
  year: 2018
  ident: 381_CR30
  publication-title: Invest Ophthalmol Vis Sci
  doi: 10.1167/iovs.17-23675
  contributor:
    fullname: IB Damgaard
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Snippet The corneal cap thickness is a vital parameter designed in small incision lenticule extraction (SMILE). The purpose was to investigate the changes in corneal...
Purpose The corneal cap thickness is a vital parameter designed in small incision lenticule extraction (SMILE). The purpose was to investigate the changes in...
PurposeThe corneal cap thickness is a vital parameter designed in small incision lenticule extraction (SMILE). The purpose was to investigate the changes in...
PURPOSEThe corneal cap thickness is a vital parameter designed in small incision lenticule extraction (SMILE). The purpose was to investigate the changes in...
Abstract Purpose The corneal cap thickness is a vital parameter designed in small incision lenticule extraction (SMILE). The purpose was to investigate the...
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SubjectTerms ACCMetrics
Automated analysis
Cap thickness
Cornea
Eye
In vivo corneal confocal microscopy
Medical imaging
Microscopy
Morphology
Myopia
Ophthalmology
Refractive surgery
Statistical analysis
Surgeons
Surgery
Surgical outcomes
Variance analysis
Visual acuity
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Title Corneal subbasal nerve plexus reinnervation and stromal cell morphology with different cap thicknesses in small incision lenticule extraction
URI https://www.ncbi.nlm.nih.gov/pubmed/38584290
https://www.proquest.com/docview/3037883771
https://search.proquest.com/docview/3034773289
https://pubmed.ncbi.nlm.nih.gov/PMC11000360
https://doaj.org/article/32879085fd414db0b9f39a7c255a5559
Volume 11
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