Kinetics, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate in healthy adult subjects - Clarke, Kieran; Tchabanenko, Kirill; Pawlosky, Robert; Carter, Emma; Todd King, M.; Musa-Veloso, Kathy; Ho, Manki; Roberts, Ashley; Robertson, Jeremy; VanItallie, Theodore B.; Veech, Richard L. (Regulatory toxicology and pharmacology, 2012)
Keywords: (R)-3-hydroxybutyl (R)-3-hydroxybutyrate; 3-hydroxybutyric acid; Acetoacetate; Adolescent; Adult; adults; blood; body weight; cognition; Dietary Supplements; Female; gastrointestinal system; half life; Humans; Hydroxybutyrates - administration & dosage; Hydroxybutyrates - adverse effects; Hydroxybutyrates - pharmacokinetics; hyperketonemia; ingestion; ketogenic diet; Ketone; ketones; Ketones - blood; Kinetics; Male; Middle Aged; milk; Safety; Tolerability; volunteers; Young Adult; β-Hydroxybutyrate; Ketone monoester; Cl/F; Cmax; GC–MS; T1/2; ECG; Tolerability; Ketone; AUC; (R)-3-hydroxybutyl (R)-3-hydroxybutyrate; β-Hydroxybutyrate; bw; Tmax; Kinetics; Safety; TMS; Acetoacetate; BMI