Intensified conditioning containing decitabine versus standard myeloablative conditioning for adult patients with KMT2A-rearranged leukemia: a multicenter retrospective study - Hu, Zhongli; Feng, Zinan; Liu, Shiqi; He, Hai; Dong, Ying; Fan, Zhiping; Li, Yiqing; Huang, Fen; Xu, Na; Liu, Can; Zeng, Yunxin; Zhu, Ping; et al. (BMC medicine, 2024)
Keywords: 5-aza-2'-deoxycytidine; Acute leukemia; Adolescent; Adult; Aged; Allo-HSCT; Allografts; Blood; Blood platelets; Bone marrow; Busulfan; Cancer; Care and treatment; China - epidemiology; Conditioning; Cyclophosphamide; Cytogenetics; Decitabine; Decitabine - administration & dosage; Decitabine - therapeutic use; Disease prevention; Female; Gene Rearrangement; Graft versus host disease; Graft-versus-host reaction; Hematopoietic Stem Cell Transplantation - methods; Hematopoietic stem cells; Histone-Lysine N-Methyltransferase - genetics; Humans; Intensified conditioning; Irradiation; KMT2A-r leukemia; Leukemia; Leukemia - therapy; Male; Medical diagnosis; Medical prognosis; Middle Aged; Myeloid-Lymphoid Leukemia Protein - genetics; Neutrophils; Patient outcomes; Patients; Relapse; Remission (Medicine); Retrospective Studies; Stem cell transplantation; Stem cells; Subgroups; Survival; Toxicity; Transplantation; Transplantation Conditioning - methods; Transplantation, Homologous - methods; Transplants & implants; Young Adult; China; Decitabine; Intensified conditioning; Allo-HSCT; KMT2A-r leukemia