Plasma FGF21 levels are increased in patients with hypothyroidism independently of lipid profile

• Published in: Endocrine Journal Vol. 60; no. 8; pp. 977 - 983
• Main Authors: Lee, Yenna, Park, Young Joo, Ahn, Hwa Young, Lim, Jung Ah, Park, Kyoung Un, Choi, Sung Hee, Park, Do Joon, Oh, Byung-Chul, Jang, Hak C., Yi, Ka Hee
• Format: Journal Article
• Language: English
• Published: Japan The Japan Endocrine Society 2013
• Subjects: Adipocytokine; Adult; Body Mass Index; Cholesterol - blood; Cholesterol, LDL - blood; Female; FGF21; Fibroblast Growth Factors; Humans; Hyperlipidemia; Hyperlipidemias - blood; Hypothyroidism; Hypothyroidism - blood; Lipids - blood; Male; Middle Aged; Subclinical hypothyroidism; Triglycerides - blood

Thyroid hormone is a potent regulator of metabolic and energy homeostasis implicated in various metabolic diseases. Fibroblast growth factor 21(FGF21) is a systemic metabolic regulator known to modulate various biological functions similar to the actions of thyroid hormone. We investigated the diffe...