Significance of Intercellular adhesion molecule-1 Lys496Glu gene polimorphism on plasma redox status regulation in laryngeal carcinoma

• Published in: Journal of cancer research and therapeutics Vol. 19; no. 7; pp. 1781 - 1787
• Main Authors: Yanar, Karolin, Atayik, Mehmet Can, Horozoğlu, Cem, Demirkol, Şeyda, Simsek, Bahadir, Verim, Aysegul, Küçükhüseyin, Özlem, Aydın, Seval, Yaylım, İlhan, Çakatay, Ufuk
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer - Medknow 01.10.2023; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd
• Edition: 2
• Subjects: Alleles; Blood proteins; Cancer; Carcinoma; Cell adhesion molecules; Development and progression; Ethylenediaminetetraacetic acid; Genes; Genetic aspects; Genetic polymorphisms; Health aspects; Humans; Intercellular Adhesion Molecule-1 - genetics; Laryngeal cancer; Laryngeal Neoplasms - genetics; Medical research; Medicine, Experimental; Original Article; Oxidation-Reduction; Oxidation-reduction reaction; Physiological aspects; Plasma; Polymorphism; Single nucleotide polymorphisms; Turkey; Gene polymorphisms; laryngeal cancer; plasma proteins; intercellular adhesion molecule 1; oxidative stress

ABSTRACT Background: Intercellular adhesion molecule-1 (ICAM-1) is a surface glycoprotein important for tumor invasion and angiogenesis. The present research is conducted to investigate whether specific gene polymorphism of ICAM-1 K469E (rs5498) and plasma redox status could be associated with laryn...