The imagined itch: brain circuitry supporting nocebo‐induced itch in atopic dermatitis patients

• Published in: Allergy (Copenhagen) Vol. 70; no. 11; pp. 1485 - 1492
• Main Authors: Napadow, V., Li, A., Loggia, M.L., Kim, J., Mawla, I., Desbordes, G., Schalock, P. C., Lerner, E. A., Tran, T. N., Ring, J., Rosen, B. R., Kaptchuk, T. J., Pfab, F.
• Format: Journal Article
• Language: English
• Published: Denmark Blackwell Publishing Ltd 01.11.2015
• Subjects: Adolescent; Adult; Allergens - immunology; atopic dermatitis; Brain - physiopathology; caudate; Dermatitis; Dermatitis, Atopic - diagnosis; Dermatitis, Atopic - psychology; Female; Humans; Magnetic Resonance Imaging; Male; Neuropsychology; nocebo; Nocebo Effect; placebo; pruritus; Pruritus - diagnosis; Pruritus - psychology; Sensory perception; Skin Tests; Young Adult; pruritus; atopic dermatitis; caudate; placebo; nocebo

Background Psychological factors are known to significantly modulate itch in patients suffering from chronic itch. Itch is also highly susceptible to both placebo and nocebo (negative placebo) effects. Brain activity likely supports nocebo‐induced itch, but is currently unknown. Methods We collected...