TopBP1 deficiency impairs V(D)J recombination during lymphocyte development - Kim, Jieun; Kyu Lee, Sung; Jeon, Yoon; Kim, Yehyun; Lee, Changjin; Ho Jeon, Sung; Shim, Jaegal; Kim, In-Hoo; Hong, Seokmann; Kim, Nayoung; Lee, Ho; Seong, Rho Hyun (The EMBO journal, 2014)
Keywords: Animals; Carrier Proteins - genetics; Carrier Proteins - immunology; Carrier Proteins - metabolism; Chromatin Immunoprecipitation; Defects; Deoxyribonucleic acid; DNA; DNA - genetics; DNA Breaks, Double-Stranded; DNA Damage; DNA Repair; EMBO19; Gene Expression; Histones - genetics; Histones - metabolism; lymphocyte development; Lymphocytes; Lymphocytes - immunology; Lymphocytes - physiology; Mice; Mice, Knockout; Natural Killer T-Cells - immunology; Natural Killer T-Cells - physiology; Precursor Cells, B-Lymphoid - immunology; Precursor Cells, B-Lymphoid - physiology; Sequence Deletion; Specific Pathogen-Free Organisms; T cell receptors; TopBP1; Transgenes; V(D)J Recombination - genetics; V(D)J Recombination - immunology; VDJ recombination; VDJ recombination; TopBP1; lymphocyte development