Regular consumption of a cocoa product improves the cardiometabolic profile in healthy and moderately hypercholesterolaemic adults

• Published in: British journal of nutrition Vol. 111; no. 1; pp. 122 - 134
• Main Authors: Sarriá, Beatriz, Martínez-López, Sara, Sierra-Cinos, José Luis, García-Diz, Luis, Mateos, Raquel, Bravo, Laura
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 14.01.2014
• Subjects: Adult; adults; anti-inflammatory activity; Anti-Inflammatory Agents - pharmacology; Anti-Inflammatory Agents - therapeutic use; Anticholesteremic Agents - pharmacology; Anticholesteremic Agents - therapeutic use; Antioxidants; Antioxidants - pharmacology; Antioxidants - therapeutic use; Biological and medical sciences; Blood Glucose - metabolism; blood lipids; Blood pressure; Blood Pressure - drug effects; blood serum; Cacao - chemistry; Carbonyl compounds; Cardiovascular Diseases - blood; Cardiovascular Diseases - prevention & control; Cardiovascular system; cell adhesion; Cell Adhesion Molecules - blood; chemokine CCL2; Cholesterol, HDL - blood; Cocoa; cocoa products; Cytokines - blood; diastolic blood pressure; Dietary fiber; Dietary Fiber - administration & dosage; Dietary Fiber - pharmacology; Dietary Fiber - therapeutic use; Feeding. Feeding behavior; Female; flavanols; Fundamental and applied biological sciences. Psychology; glucose; Health Status; Heart rate; Heart Rate - drug effects; high density lipoprotein cholesterol; Human and Clinical Nutrition; Humans; hypercholesterolemia; Hypercholesterolemia - blood; Hypercholesterolemia - diet therapy; Hypoglycemic Agents - pharmacology; Hypoglycemic Agents - therapeutic use; interleukin-10; interleukin-1beta; interleukin-6; interleukin-8; Male; malondialdehyde; Malondialdehyde - blood; Milk; Nutrition; oxygen radical absorbance capacity; physical activity; Phytotherapy; Plant Preparations - pharmacology; Plant Preparations - therapeutic use; polyphenols; Polyphenols - pharmacology; Polyphenols - therapeutic use; Protein Carbonylation - drug effects; Reference Values; tumor necrosis factor-alpha; Vertebrates: anatomy and physiology, studies on body, several organs or systems; volunteers; weight gain; Young Adult; Antioxidants; Cytokines; HDL-cholesterol; Cocoa polyphenols; Adhesion molecules; Dietary fibre; Inflammation; Nutrition; Cytokine; Antioxidant; Adhesion; Cocoa; Profile; Feeding; Micronutrient; Molecules; Polyphenol; Cholesterol HDL; Food intake; Proanthocyanidin

Cocoa products present great health potential due to their high content of polyphenols, mainly of flavanols. However, the antioxidant, anti-inflammatory and other health effects of regularly consuming cocoa products seem to depend on the intake and health status of the consumer, etc. and need to be...