Anterior Leaflet Laceration to Prevent Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Replacement

• Published in: Journal of the American College of Cardiology Vol. 73; no. 20; pp. 2521 - 2534
• Main Authors: Khan, Jaffar M., Babaliaros, Vasilis C., Greenbaum, Adam B., Foerst, Jason R., Yazdani, Shahram, McCabe, James M., Paone, Gaetano, Eng, Marvin H., Leshnower, Bradley G., Gleason, Patrick T., Chen, Marcus Y., Wang, Dee Dee, Tian, Xin, Stine, Annette M., Rogers, Toby, Lederman, Robert J.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 28.05.2019; Elsevier Limited
• Subjects: Aged; Aged, 80 and over; Alcohol; Calcification; Cardiac Catheterization - methods; Cardiology; Cardiovascular; Cardiovascular diseases; Catheters; Echocardiography; Echocardiography, Transesophageal; Electrosurgery - methods; Female; Follow-Up Studies; Heart; Heart Septum - diagnostic imaging; Heart Septum - surgery; Heart Valve Diseases - complications; Heart Valve Diseases - diagnosis; Heart Valve Diseases - surgery; Heart Valve Prosthesis Implantation - methods; Humans; Intraoperative Period; Laboratories; Male; Middle Aged; mitral annular calcification; Mitral valve; Mitral Valve - diagnostic imaging; Mitral Valve - surgery; Mortality; Prospective Studies; structural heart disease; Surgery; Survival; Tomography; Tomography, X-Ray Computed; transcatheter electrosurgery; transcatheter mitral valve replacement; transseptal interventions; Treatment Outcome; valve-in-ring; Ventricle; Ventricular Outflow Obstruction - diagnosis; Ventricular Outflow Obstruction - etiology; Ventricular Outflow Obstruction - prevention & control; United States > US; mitral annular calcification; transcatheter mitral valve replacement; LAMPOON; TMVR; NHLBI; transseptal interventions; PVL; transcatheter electrosurgery; valve-in-ring; LVOT; structural heart disease; MAC; intentional laceration of the anterior mitral leaflet to prevent left ventricular outflow obstruction; left ventricular outflow tract; National Heart Lung and Blood Institute; paravalvular leak

Left ventricular outflow tract (LVOT) obstruction is a leading cause of mortality and exclusion from transcatheter mitral valve replacement (TMVR). Intentional laceration of the anterior mitral valve leaflet to prevent LVOT obstruction (LAMPOON) is a transcatheter mimic of surgical chord-sparing lea...