Transient receptor potential vanilloid 4–expressing macrophages and keratinocytes contribute differentially to allergic and nonallergic chronic itch - Luo, Jialie; Feng, Jing; Yu, Guang; Yang, Pu; Mack, Madison R.; Du, Junhui; Yu, Weihua; Qian, Aihua; Zhang, Yujin; Liu, Shenbin; Yin, Shijin; Xu, Amy; et al. (Journal of allergy and clinical immunology, 2018)
Keywords: Allergies; Animal models; Animals; Biopsy; Calcium imaging; Cancer surgery; Chronic Disease; chronic itch; Clonal deletion; Contact dermatitis; Dendritic cells; Dermatitis; Dermatitis, Allergic Contact - genetics; Dermatitis, Allergic Contact - immunology; Dermatitis, Allergic Contact - pathology; Dermis - immunology; Dermis - pathology; Female; Flow cytometry; Gene Expression Regulation - genetics; Gene Expression Regulation - immunology; Hepatitis; Humans; Immunofluorescence; keratinocyte; Keratinocytes; Keratinocytes - immunology; Keratinocytes - pathology; Laboratories; macrophage; Macrophages; Macrophages - immunology; Macrophages - pathology; Male; Mice; Mice, Knockout; Neurons; Polymerase chain reaction; Pruritus; Pruritus - genetics; Pruritus - immunology; Pruritus - pathology; Rodents; Sensory neurons; Skin; Skin cancer; Spinal cord; Stem cells; Transient receptor potential proteins; Transient receptor potential vanilloid 4; TRPV Cation Channels - genetics; TRPV Cation Channels - immunology; ACD; eGFP; PBS+TX; [Ca2+]i; chronic itch; macrophage; DTX; SADBE; CIP; Transient receptor potential vanilloid 4; TPH; GFP; Ct; AEW; Htr7; keratinocyte; TRPV4; pCPA; DRG; Htr2a; IRB; 5-HT; GAPDH; WT