Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses - Chiba, Shiho; Ikushima, Hiroaki; Ueki, Hiroshi; Yanai, Hideyuki; Kimura, Yoshitaka; Hangai, Sho; Nishio, Junko; Negishi, Hideo; Tamura, Tomohiko; Saijo, Shinobu; Iwakura, Yoichiro; Taniguchi, Tadatsugu (eLife, 2014)
Keywords: Animals; Cell Communication; Cell Line, Tumor; Cell Proliferation; Cytotoxicity, Immunologic; Dectin-1; Dendritic cells; Dendritic Cells - metabolism; Effector cells; Flow cytometry; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Immune system; Immunity, Innate - immunology; Immunology; Innate immunity; Interferon Regulatory Factors - metabolism; IRF; Killer Cells, Natural - immunology; Lectins, C-Type - deficiency; Lectins, C-Type - metabolism; Ligands; Lungs; Macrophages; Macrophages - metabolism; Melanoma; Melanoma, Experimental - genetics; Melanoma, Experimental - immunology; Melanoma, Experimental - pathology; Metastasis; Mice, Inbred C57BL; Models, Immunological; Natural killer cells; NK cell; Polysaccharides - chemistry; Polysaccharides - metabolism; Protein Binding; RNA, Messenger - genetics; RNA, Messenger - metabolism; Rodents; Science; Signal Transduction - immunology; Transcription activation; Transcription factors; Tumor cells; mouse; Dectin-1; innate immunity; IRF; immunology; NK cell