Progesterone and vitamin D: Improvement after traumatic brain injury in middle-aged rats
Progesterone (PROG) and vitamin D hormone (VDH) have both shown promise in treating traumatic brain injury (TBI). Both modulate apoptosis, inflammation, oxidative stress, and excitotoxicity. We investigated whether 21days of VDH deficiency would alter cognitive behavior after TBI and whether combine...
Saved in:
| Published in | Hormones and behavior Vol. 64; no. 3; pp. 527 - 538 |
|---|---|
| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Amsterdam
Elsevier Inc
01.08.2013
Elsevier Elsevier BV |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Progesterone (PROG) and vitamin D hormone (VDH) have both shown promise in treating traumatic brain injury (TBI). Both modulate apoptosis, inflammation, oxidative stress, and excitotoxicity. We investigated whether 21days of VDH deficiency would alter cognitive behavior after TBI and whether combined PROG and VDH would improve behavioral and morphological outcomes more than either hormone alone in VDH-deficient middle-aged rats given bilateral contusions of the medial frontal cortex. PROG (16mg/kg) and VDH (5μg/kg) were injected intraperitoneally 1h post-injury. Eight additional doses of PROG were injected subcutaneously over 7days post-injury. VDH deficiency itself did not significantly reduce baseline behavioral functions or aggravate impaired cognitive outcomes. Combination therapy showed moderate improvement in preserving spatial and reference memory but was not significantly better than PROG monotherapy. However, combination therapy significantly reduced neuronal loss and the proliferation of reactive astrocytes, and showed better efficacy compared to VDH or PROG alone in preventing MAP-2 degradation. VDH+PROG combination therapy may attenuate some of the potential long-term, subtle, pathophysiological consequences of brain injury in older subjects.
•TBI causes a cascade of systemic toxic events in the brain and throughout the body.•Drugs acting on multiple genomic and metabolic pathways could solve this problem.•Combined progesterone+VDH therapy improved spatial and reference memory after TBI.•Progesterone+VDH therapy reduced reactive astrocyte proliferation and neuron loss. |
|---|---|
| AbstractList | Progesterone (PROG) and vitamin D hormone (VDH) have both shown promise in treating traumatic brain injury (TBI). Both modulate apoptosis, inflammation, oxidative stress, and excitotoxicity. We investigated whether 21days of VDH deficiency would alter cognitive behavior after TBI and whether combined PROG and VDH would improve behavioral and morphological outcomes more than either hormone alone in VDH-deficient middle-aged rats given bilateral contusions of the medial frontal cortex. PROG (16mg/kg) and VDH (5μg/kg) were injected intraperitoneally 1h post-injury. Eight additional doses of PROG were injected subcutaneously over 7days post-injury. VDH deficiency itself did not significantly reduce baseline behavioral functions or aggravate impaired cognitive outcomes. Combination therapy showed moderate improvement in preserving spatial and reference memory but was not significantly better than PROG monotherapy. However, combination therapy significantly reduced neuronal loss and the proliferation of reactive astrocytes, and showed better efficacy compared to VDH or PROG alone in preventing MAP-2 degradation. VDH+PROG combination therapy may attenuate some of the potential long-term, subtle, pathophysiological consequences of brain injury in older subjects.
•TBI causes a cascade of systemic toxic events in the brain and throughout the body.•Drugs acting on multiple genomic and metabolic pathways could solve this problem.•Combined progesterone+VDH therapy improved spatial and reference memory after TBI.•Progesterone+VDH therapy reduced reactive astrocyte proliferation and neuron loss. Progesterone (PROG) and vitamin D hormone (VDH) have both shown promise in treating traumatic brain injury (TBI). Both modulate apoptosis, inflammation, oxidative stress, and excitotoxicity. We investigated whether 21 days of VDH deficiency would alter cognitive behavior after TBI and whether combined PROG and VDH would improve behavioral and morphological outcomes more than either hormone alone in VDH-deficient middle-aged rats given bilateral contusions of the medial frontal cortex. PROG (16 mg/kg) and VDH (5 μg/kg) were injected intraperitoneally 1 h post-injury. Eight additional doses of PROG were injected subcutaneously over 7 days post-injury. VDH deficiency itself did not significantly reduce baseline behavioral functions or aggravate impaired cognitive outcomes. Combination therapy showed moderate improvement in preserving spatial and reference memory but was not significantly better than PROG monotherapy. However, combination therapy significantly reduced neuronal loss and the proliferation of reactive astrocytes, and showed better efficacy compared to VDH or PROG alone in preventing MAP-2 degradation. VDH+PROG combination therapy may attenuate some of the potential long-term, subtle, pathophysiological consequences of brain injury in older subjects. Progesterone (PROG) and vitamin D hormone (VDH) have both shown promise in treating traumatic brain injury (TBI). Both modulate apoptosis, inflammation, oxidative stress, and excitotoxicity. We investigated whether 21 days of VDH deficiency would alter cognitive behavior after TBI and whether combined PROG and VDH would improve behavioral and morphological outcomes more than either hormone alone in VDH-deficient middle-aged rats given bilateral contusions of the medial frontal cortex. PROG (16 mg/kg) and VDH (5 μg/kg) were injected intraperitoneally 1 h post-injury. Eight additional doses of PROG were injected subcutaneously over 7 days post-injury. VDH deficiency itself did not significantly reduce baseline behavioral functions or aggravate impaired cognitive outcomes. Combination therapy showed moderate improvement in preserving spatial and reference memory but was not significantly better than PROG monotherapy. However, combination therapy significantly reduced neuronal loss and the proliferation of reactive astrocytes, and showed better efficacy compared to VDH or PROG alone in preventing MAP-2 degradation. VDH+PROG combination therapy may attenuate some of the potential long-term, subtle, pathophysiological consequences of brain injury in older subjects.Progesterone (PROG) and vitamin D hormone (VDH) have both shown promise in treating traumatic brain injury (TBI). Both modulate apoptosis, inflammation, oxidative stress, and excitotoxicity. We investigated whether 21 days of VDH deficiency would alter cognitive behavior after TBI and whether combined PROG and VDH would improve behavioral and morphological outcomes more than either hormone alone in VDH-deficient middle-aged rats given bilateral contusions of the medial frontal cortex. PROG (16 mg/kg) and VDH (5 μg/kg) were injected intraperitoneally 1 h post-injury. Eight additional doses of PROG were injected subcutaneously over 7 days post-injury. VDH deficiency itself did not significantly reduce baseline behavioral functions or aggravate impaired cognitive outcomes. Combination therapy showed moderate improvement in preserving spatial and reference memory but was not significantly better than PROG monotherapy. However, combination therapy significantly reduced neuronal loss and the proliferation of reactive astrocytes, and showed better efficacy compared to VDH or PROG alone in preventing MAP-2 degradation. VDH+PROG combination therapy may attenuate some of the potential long-term, subtle, pathophysiological consequences of brain injury in older subjects. Progesterone (PROG) and vitamin D hormone (VDH) have both shown promise in treating traumatic brain injury (TBI). Both modulate apoptosis, inflammation, oxidative stress, and excitotoxicity. We investigated whether 21days of VDH deficiency would alter cognitive behavior after TBI and whether combined PROG and VDH would improve behavioral and morphological outcomes more than either hormone alone in VDH-deficient middle-aged rats given bilateral contusions of the medial frontal cortex. PROG (16mg/kg) and VDH (5μg/kg) were injected intraperitoneally 1h post-injury. Eight additional doses of PROG were injected subcutaneously over 7days post-injury. VDH deficiency itself did not significantly reduce baseline behavioral functions or aggravate impaired cognitive outcomes. Combination therapy showed moderate improvement in preserving spatial and reference memory but was not significantly better than PROG monotherapy. However, combination therapy significantly reduced neuronal loss and the proliferation of reactive astrocytes, and showed better efficacy compared to VDH or PROG alone in preventing MAP-2 degradation. VDH+PROG combination therapy may attenuate some of the potential long-term, subtle, pathophysiological consequences of brain injury in older subjects. Progesterone (PROG) and vitamin D hormone (VDH) have both shown promise in treating traumatic brain injury (TBI). Both modulate apoptosis, inflammation, oxidative stress, and excitotoxicity. We investigated whether 21days of VDH deficiency would alter cognitive behavior after TBI and whether combined PROG and VDH would improve behavioral and morphological outcomes more than either hormone alone in VDH-deficient middle-aged rats given bilateral contusions of the medial frontal cortex. PROG (16mg/kg) and VDH (5μg/kg) were injected intraperitoneally 1h post-injury. Eight additional doses of PROG were injected subcutaneously over 7days post-injury. VDH deficiency itself did not significantly reduce baseline behavioral functions or aggravate impaired cognitive outcomes. Combination therapy showed moderate improvement in preserving spatial and reference memory but was not significantly better than PROG monotherapy. However, combination therapy significantly reduced neuronal loss and the proliferation of reactive astrocytes, and showed better efficacy compared to VDH or PROG alone in preventing MAP-2 degradation. VDH+PROG combination therapy may attenuate some of the potential long-term, subtle, pathophysiological consequences of brain injury in older subjects. * TBI causes a cascade of systemic toxic events in the brain and throughout the body. * Drugs acting on multiple genomic and metabolic pathways could solve this problem. * Combined progesterone+VDH therapy improved spatial and reference memory after TBI. * Progesterone+VDH therapy reduced reactive astrocyte proliferation and neuron loss. Progesterone (PROG) and vitamin D hormone (VDH) have both shown promise in treating traumatic brain injury (TBI). Both modulate apoptosis, inflammation, oxidative stress, and excitotoxicity. We investigated whether 21 days of VDH deficiency would alter cognitive behavior after TBI and whether combined PROG and VDH would improve behavioral and morphological outcomes more than either hormone alone in VDH-deficient middle-aged rats given bilateral contusions of the medial frontal cortex. PROG (16 mg/kg) and VDH (5 µg/kg) were injected intraperitoneally 1 hour post-injury. Eight additional doses of PROG were injected subcutaneously over 7 days post-injury. VDH deficiency itself did not significantly reduce baseline behavioral functions or aggravate impaired cognitive outcomes. Combination therapy showed moderate improvement in preserving spatial and reference memory but was not significantly better than PROG monotherapy. However, combination therapy significantly reduced neuronal loss and the proliferation of reactive astrocytes, and showed better efficacy compared to VDH or PROG alone in preventing MAP-2 degradation. VDH+PROG combination therapy may attenuate some of the potential long-term, subtle, pathophysiological consequences of brain injury in older subjects. |
| Author | Tang, Huiling Sayeed, Iqbal Hua, Fang Yousuf, Seema Atif, Fahim Wang, Xiaojing Wang, Jun Chen, Zhengjia Stein, Donald G. |
| AuthorAffiliation | 1 Department of Emergency Medicine, Emory University, Atlanta, GA 30322, USA 2 Department of Biostatistics & Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA |
| AuthorAffiliation_xml | – name: 2 Department of Biostatistics & Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA – name: 1 Department of Emergency Medicine, Emory University, Atlanta, GA 30322, USA |
| Author_xml | – sequence: 1 givenname: Huiling surname: Tang fullname: Tang, Huiling organization: Department of Emergency Medicine, Emory University, Atlanta, GA 30322, USA – sequence: 2 givenname: Fang surname: Hua fullname: Hua, Fang organization: Department of Emergency Medicine, Emory University, Atlanta, GA 30322, USA – sequence: 3 givenname: Jun surname: Wang fullname: Wang, Jun organization: Department of Emergency Medicine, Emory University, Atlanta, GA 30322, USA – sequence: 4 givenname: Iqbal surname: Sayeed fullname: Sayeed, Iqbal organization: Department of Emergency Medicine, Emory University, Atlanta, GA 30322, USA – sequence: 5 givenname: Xiaojing surname: Wang fullname: Wang, Xiaojing organization: Department of Biostatistics & Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA – sequence: 6 givenname: Zhengjia surname: Chen fullname: Chen, Zhengjia organization: Department of Biostatistics & Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA – sequence: 7 givenname: Seema surname: Yousuf fullname: Yousuf, Seema organization: Department of Emergency Medicine, Emory University, Atlanta, GA 30322, USA – sequence: 8 givenname: Fahim surname: Atif fullname: Atif, Fahim organization: Department of Emergency Medicine, Emory University, Atlanta, GA 30322, USA – sequence: 9 givenname: Donald G. surname: Stein fullname: Stein, Donald G. email: dstei04@emory.edu organization: Department of Emergency Medicine, Emory University, Atlanta, GA 30322, USA |
| BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=27853975$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/23896206$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkl1rFDEUhoNU7Lb6CwQZEKE3M-ZjkpkICtL6USjohULvQiY5s5tlJlmTmYX992bdtWov6tUh5Hlfzsd7hk588IDQc4Irgol4va52qw5WFcWEVVhUGMtHaEGw5KVoRXOCFhiTtuRY3J6is5TW-Ul4XT9Bp5S1UlAsFuj2awxLSBPEbF5ob4utm_TofHH1prgeNzFsYQQ_FbrPTDFFPY96cqboos6Q8-s57nIpRmftAKVegi2intJT9LjXQ4Jnx3qOvn_88O3yc3nz5dP15fub0vCaT6XsgUrBeM-l5YbiTkDbCdpiyoTAmotGGioEtR0TzNTMApDGQEM6W_ea9-wcvTv4buZuBGtyr1EPahPdqONOBe3Uvz_erdQybBVrGat5nQ0ujgYx_JjzKtTokoFh0B7CnBSpWcubzLYZfXkPXYc5-jyeIpwLKTFu5INUzRpGGkr21Iu_-75r-PdpMvDqCOhk9NBH7Y1Lf7im5Uw2PHPswJkYUorQ3yEEq31Q1Fr9CoraB0VhoXJQskreU5l898mF_ZLc8B_t24MW8l23DqJKxoE3YF0EMykb3IP6n97x2Wg |
| CODEN | HOBEAO |
| CitedBy_id | crossref_primary_10_1016_j_yfrne_2019_100788 crossref_primary_10_1007_s40261_020_00896_5 crossref_primary_10_1007_s12035_022_02970_9 crossref_primary_10_1089_neu_2014_3855 crossref_primary_10_3892_ijmm_2017_3249 crossref_primary_10_1038_s41598_022_09326_2 crossref_primary_10_1007_s11356_021_18391_5 crossref_primary_10_1007_s11011_018_0371_7 crossref_primary_10_1080_00207454_2021_1924706 crossref_primary_10_3390_ijms231911193 crossref_primary_10_3390_jcm12062179 crossref_primary_10_1016_j_yfrne_2018_03_006 crossref_primary_10_1016_j_brainres_2015_12_030 crossref_primary_10_1016_j_jsbmb_2015_11_010 crossref_primary_10_1177_0271678X16665623 crossref_primary_10_26442_2079_5696_20_1_117_125 crossref_primary_10_3390_ijms15010309 crossref_primary_10_3390_biology8020030 crossref_primary_10_1016_j_expneurol_2015_05_024 crossref_primary_10_1016_j_neuropharm_2018_04_006 crossref_primary_10_1080_1028415X_2024_2404782 crossref_primary_10_1089_neu_2021_0105 crossref_primary_10_1089_neu_2016_4845 crossref_primary_10_1016_j_pneurobio_2016_06_002 crossref_primary_10_1186_s12245_020_00289_7 crossref_primary_10_1016_j_brainres_2013_11_030 crossref_primary_10_1038_s41598_020_73227_5 crossref_primary_10_1016_j_neuint_2024_105741 crossref_primary_10_3109_02699052_2016_1147081 crossref_primary_10_1016_j_heliyon_2023_e22067 crossref_primary_10_1016_j_pbb_2020_172971 crossref_primary_10_1080_23279095_2020_1842409 crossref_primary_10_1016_j_neuropharm_2016_05_017 crossref_primary_10_1016_j_autrev_2016_07_002 crossref_primary_10_3109_02699052_2014_943289 crossref_primary_10_1016_j_neuropharm_2020_108327 crossref_primary_10_14218_ERHM_2017_00029 crossref_primary_10_1590_1678_4324_2023220156 crossref_primary_10_1016_j_pneurobio_2016_03_010 crossref_primary_10_1007_s12975_017_0588_5 crossref_primary_10_1016_j_expneurol_2018_05_013 crossref_primary_10_2174_1874467214666210910114324 crossref_primary_10_3109_02699052_2015_1035330 crossref_primary_10_1007_s13311_023_01428_7 crossref_primary_10_1016_j_jsbmb_2015_06_007 crossref_primary_10_25259_SNI_776_2023 crossref_primary_10_1111_cen_13045 |
| Cites_doi | 10.1038/nrn1323 10.1186/1742-2094-9-244 10.1523/JNEUROSCI.21-01-00098.2001 10.1267/ahc.09018 10.1016/S0027-5107(01)00080-X 10.1089/neu.2007.0294 10.1177/1073858402239587 10.1016/0197-4580(89)90047-X 10.1016/j.brainres.2013.02.020 10.1146/annurev.psych.48.1.339 10.1016/j.brainres.2010.10.099 10.1161/STROKEAHA.111.636910 10.1080/02688690701364781 10.1111/nan.12020 10.1016/S0197-4580(02)00004-0 10.1016/j.jsbmb.2007.03.032 10.1016/j.neurobiolaging.2009.04.017 10.1016/S0306-4522(99)00418-2 10.1016/S0165-0173(01)00135-7 10.1016/j.yhbeh.2012.03.018 10.1089/neu.2010.1686 10.1016/j.bbr.2005.02.015 10.1001/archneurol.2011.30 10.1096/fj.07-9326rev 10.1016/j.expneurol.2006.02.137 10.1016/j.it.2007.01.005 10.1007/PL00012396 10.1016/S0197-4580(89)80008-9 10.1196/annals.1344.028 10.1016/j.pmrj.2011.03.010 10.1038/nn1885 10.1007/s00702-009-0241-x 10.1016/0197-4580(94)00155-3 10.1053/j.ajkd.2005.04.015 10.1161/STROKEAHA.112.651752 10.1016/j.neurobiolaging.2007.07.001 10.1016/j.yhbeh.2012.02.017 10.1002/cm.970270305 10.1016/j.yfrne.2012.07.001 10.1089/neu.2008.0794 10.1016/S0968-0004(98)01245-6 10.1001/archneur.65.10.1348 10.1212/WNL.0b013e3181beecd3 10.1002/mds.21317 10.1210/en.2011-1783 10.1016/j.neulet.2004.12.029 10.1006/hbeh.1999.1560 10.1016/j.bbr.2010.01.005 10.1016/j.pbb.2003.07.003 10.1016/j.mam.2008.05.001 10.2174/092986709787846523 10.1016/j.neuropharm.2008.04.023 10.2119/molmed.2009.00016 10.1210/en.2009-1487 10.1210/en.2012-1412 10.1089/neu.2011.2246 10.1016/j.brainres.2005.05.004 10.1210/en.2012-1138 10.1037/0735-7044.108.3.624 10.1371/journal.pone.0029354 10.1016/j.neuropharm.2012.10.004 10.1186/1742-2094-8-42 10.1016/j.bone.2004.02.014 10.1006/hbeh.2000.1626 10.1016/j.psyneuen.2012.03.026 10.1093/ajcn/80.6.1706S 10.1089/neu.2006.0024 |
| ContentType | Journal Article |
| Copyright | 2013 Elsevier Inc. 2015 INIST-CNRS 2013 Elsevier Inc. All rights reserved. Copyright © 2013 Elsevier B.V. All rights reserved. 2013 Elsevier Inc. All rights reserved. 2013 |
| Copyright_xml | – notice: 2013 Elsevier Inc. – notice: 2015 INIST-CNRS – notice: 2013 Elsevier Inc. All rights reserved. – notice: Copyright © 2013 Elsevier B.V. All rights reserved. – notice: 2013 Elsevier Inc. All rights reserved. 2013 |
| DBID | AAYXX CITATION IQODW CGR CUY CVF ECM EIF NPM 7QG 7TK K9. 7X8 5PM |
| DOI | 10.1016/j.yhbeh.2013.06.009 |
| DatabaseName | CrossRef Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Animal Behavior Abstracts Neurosciences Abstracts ProQuest Health & Medical Complete (Alumni) MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest Health & Medical Complete (Alumni) Neurosciences Abstracts Animal Behavior Abstracts MEDLINE - Academic |
| DatabaseTitleList | MEDLINE MEDLINE - Academic ProQuest Health & Medical Complete (Alumni) ProQuest Health & Medical Complete (Alumni) |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Anatomy & Physiology |
| EISSN | 1095-6867 |
| EndPage | 538 |
| ExternalDocumentID | PMC3833454 3415279351 3083942611 23896206 27853975 10_1016_j_yhbeh_2013_06_009 S0018506X13001396 |
| Genre | Journal Article Research Support, N.I.H., Extramural News |
| GrantInformation_xml | – fundername: NICHD NIH HHS grantid: R01 HD061971 – fundername: NICHD NIH HHS grantid: 1R01HD061971 – fundername: National Institute of Child Health & Human Development : NICHD grantid: R01 HD061971 || HD |
| GroupedDBID | --- --K --M -DZ -~X .55 .GJ .~1 0R~ 1B1 1RT 1~. 1~5 29I 4.4 457 4G. 53G 5GY 5VS 7-5 71M 8P~ 9JM 9JO AACTN AADFP AADPK AAEDT AAEDW AAGJA AAGUQ AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AAXLA AAXUO ABCQJ ABFNM ABFRF ABGSF ABIVO ABJNI ABMAC ABOYX ABUDA ABXDB ABYKQ ACDAQ ACGFS ACNCT ACPRK ACRLP ACXNI ADBBV ADEZE ADFGL ADMUD ADUVX AEBSH AEFWE AEHWI AEKER AENEX AFKWA AFTJW AFXIZ AFYLN AGHFR AGRDE AGUBO AGWIK AGYEJ AHHHB AHMBA AHPSJ AIEXJ AIKHN AITUG AJBFU AJOXV ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC C45 CAG COF CS3 DM4 DOVZS EBS EFBJH EFLBG EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q GBLVA HLW HMQ HMW HVGLF HZ~ H~9 IHE J1W KOM LG5 LX2 M2U M3U M41 MO0 MOBAO MVM N9A O-L O9- OAUVE OKEIE OVD OZT P-8 P-9 PC. PQQKQ Q38 R2- RIG ROL RPZ SBG SCC SDF SDG SDP SES SEW SNS SPCBC SPS SSB SSN SSU SSY SSZ T5K TEORI TWZ UAP UNMZH UQL VQP WH7 WUQ X7M XOL XPP ZGI ZKB ZMT ZU3 ~02 ~G- AATTM AAXKI AAYWO AAYXX ABWVN ACRPL ACVFH ADCNI ADNMO ADXHL AEIPS AEUPX AFJKZ AFPUW AGCQF AGQPQ AGRNS AIGII AIIUN AKBMS AKRWK AKYEP ANKPU APXCP BNPGV CITATION SSH IQODW CGR CUY CVF ECM EIF NPM 7QG 7TK EFKBS K9. 7X8 5PM |
| ID | FETCH-LOGICAL-c545t-9fe29635f59d5c20b6e8b628023660a5679c2662db363c43dee17ce71bd4fa5f3 |
| IEDL.DBID | .~1 |
| ISSN | 0018-506X 1095-6867 |
| IngestDate | Thu Aug 21 18:07:12 EDT 2025 Mon Jul 21 10:07:30 EDT 2025 Mon Jul 14 08:41:12 EDT 2025 Mon Jul 14 10:45:07 EDT 2025 Thu Apr 03 06:55:21 EDT 2025 Wed Apr 02 07:23:14 EDT 2025 Tue Jul 01 01:36:14 EDT 2025 Thu Apr 24 23:06:45 EDT 2025 Fri Feb 23 02:30:38 EST 2024 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 3 |
| Keywords | Vitamin D deficiency Traumatic brain injury Functional repair Vitamin D3 hormone Aging Progesterone Combination treatments Senescence Rat Progestagen Vitamin D Adult Repair Nutritional status Human Nervous system diseases Rodentia Nutrition disorder Ovarian hormone Micronutrient Vertebrata Mammalia Animal Combined treatment Head trauma Sex steroid hormone |
| Language | English |
| License | CC BY 4.0 2013 Elsevier Inc. All rights reserved. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c545t-9fe29635f59d5c20b6e8b628023660a5679c2662db363c43dee17ce71bd4fa5f3 |
| Notes | SourceType-Scholarly Journals-1 ObjectType-News-1 content type line 14 ObjectType-Article-2 ObjectType-Feature-1 ObjectType-Article-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/3833454 |
| PMID | 23896206 |
| PQID | 1437317219 |
| PQPubID | 45959 |
| PageCount | 12 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_3833454 proquest_miscellaneous_1438573348 proquest_journals_1556990079 proquest_journals_1437317219 pubmed_primary_23896206 pascalfrancis_primary_27853975 crossref_primary_10_1016_j_yhbeh_2013_06_009 crossref_citationtrail_10_1016_j_yhbeh_2013_06_009 elsevier_sciencedirect_doi_10_1016_j_yhbeh_2013_06_009 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2013-08-01 |
| PublicationDateYYYYMMDD | 2013-08-01 |
| PublicationDate_xml | – month: 08 year: 2013 text: 2013-08-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | Amsterdam |
| PublicationPlace_xml | – name: Amsterdam – name: United States – name: New York |
| PublicationTitle | Hormones and behavior |
| PublicationTitleAlternate | Horm Behav |
| PublicationYear | 2013 |
| Publisher | Elsevier Inc Elsevier Elsevier BV |
| Publisher_xml | – name: Elsevier Inc – name: Elsevier – name: Elsevier BV |
| References | Margulies, Hicks (bb0260) 2009; 26 Balden, Selvamani, Sohrabji (bb0365) 2012; 153 Fernandes de Abreu, Nivet, Baril, Khrestchatisky, Roman, Féron (bb0155) 2010; 208 Atif, Yousuf, Sayeed, Ishrat, Hua, Stein (bb0360) 2013; 67 Cutler, Vanlandingham, Stein (bb0090) 2006; 200 Cutler, Cekic, Miller, Wali, VanLandingham, Stein (bb0095) 2007; 24 Hua, Reiss, Tang, Wang, Fowler, Sayeed, Stein (bb0210) 2012; 61 Kuningas, Mooijaart, Jolles, Slagboom, Westendorp, van Heemst (bb0230) 2009; 30 Deluca, Kimball, Kolasinski, Ramagopalan, Ebers (bb0380) 2013 Lin, Chen, Chao (bb0240) 2005; 1053 Baldi, Efoudebe, Lorenzini, Bucherelli (bb0030) 2005; 378 Minasyan, Keisala, Lou, Kalueff, Tuohimaa (bb0280) 2007; 104 McCann, Ames (bb0275) 2008; 22 Cai, Zhu, Furuya, Li, Sokabe, Chen (bb0055) 2008; 55 Chisholm, Juraska (bb0375) 2013; 1514C Gage, Dunnett, Bjorklund (bb0170) 1989; 10 Brewer, Thibault, Chen, Langub, Landfield, Porter (bb0040) 2001; 21 Eyles, Burne, McGrath (bb0140) 2013; 34 Hedden, Gabrieli (bb0195) 2004; 5 Markowska, Stone, Ingram, Reynolds, Gold, Conti, Pontecorvo, Wenk, Olton (bb0270) 1989; 10 Vallée, Mayo, Le Moal (bb0345) 2001; 37 Annweiler, Schott, Allali, Bridenbaugh, Kressig, Allain, Herrmann, Beauchet (bb0005) 2010; 74 Maas, Marmarou, Murray, Teasdale, Steyerberg (bb0255) 2007; 24 Drewes, Ebneth, Mandelkow (bb0115) 1998; 23 Velíšková, Desantis (bb0400) 2013; 63 Evatt, Delong, Khazai, Rosen, Triche, Tangpricha (bb0130) 2008; 65 Stein, Cekic (bb0330) 2011; 3 Narayanan, Allen, Gaddy, Bloomfield, Smith, Weigel (bb0285) 2004; 35 Frick, Baxter, Markowska, Olton, Price (bb0160) 1995; 16 Sarkaki, Khaksari, Soltani, Shahrokhi, Mahmoodi (bb0310) 2013; 30 Gallagher, Rapp (bb0180) 1997; 48 Holick (bb0200) 2005; 45 Solomon, Gianforcaro, Hamadeh (bb0390) 2011; 6 Valtueña, Gracia-Marco, Huybrechts, Breidenassel, Ferrari, Gottrand, Dallongeville, Sioen, Gutierrez, Kersting, Kafatos, Manios, Widhalm, Moreno, González-Gross (bb0395) 2013 Becker, Eyles, McGrath, Grecksch (bb0035) 2005; 161 Chatterjee (bb0070) 2001; 475 Chisholm, Packard, Koss, Juraska (bb0085) 2012; 153 Hua, Wang, Ishrat, Wei, Atif, Sayeed, Stein (bb0215) 2011; 8 Sun, Pan, Hu, Manson, Rexrode (bb0335) 2012; 43 Felmingham, Fong, Bryant (bb0150) 2012; 37 Staffa, Ondruschka, Franke, Dreßler (bb0325) 2012; 29 Briones, Darwish (bb0370) 2012; 9 Chesler, Juraska (bb0075) 2000; 38 Paulson, Robinson (bb0300) 1994; 108 Ehara, Ueda (bb0120) 2009; 42 Luckhaus, Mahabadi, Grass-Kapanke, Jänner, Willenberg, Jäger, Supprian, Fehsel (bb0250) 2009; 116 Diamond, Ho, Rohl, Meerkin (bb0110) 2005; 183 Sharma, Kress, Shafit-Zagardo (bb0315) 1994; 27 Farina, Aloisi, Meinl (bb0145) 2007; 28 Hu, Li, Fang, Wai, Yew (bb0205) 2009; 16 Buell, Dawson-Hughes (bb0050) 2010; 29 Wali, Sayeed, Stein (bb0355) 2011; 29 Di Giorgio, Carrasco, Siao, Maniatis, Eggan (bb0105) 2007; 10 Evatt, DeLong, Kumari, Auinger, McDermott, Tangpricha, Parkinson Study Group DATATOP Investigators (bb0135) 2011; 68 Goss, Hoffman, Stein (bb0185) 2003; 76 Liu, Margaill, Zhang, Labombarda, Coqueran, Delespierre, Liere, Marchand-Leroux, O'Malley, Lydon, De Nicola, Sitruk-Ware, Mattern, Plotkine, Schumacher, Guennoun (bb0385) 2012; 153 Heaney (bb0190) 2004; 80 Frick, Burlingame, Arters, Berger-Sweeney (bb0165) 2000; 95 Kojima, Bell, Abbott, Launer, Chen, Motonaga, Ross, Curb, Masaki (bb0225) 2012; 43 Pettus, Wright, Stein, Hoffman (bb0305) 2005; 1049 Cekic, Cutler, VanLandingham, Stein (bb0065) 2011; 32 Paris, Walf, Frye (bb0295) 2011; 1379 John, Lee, Brosnan (bb0220) 2003; 9 Carroll, Rosario, Villamagna, Pike (bb0060) 2010; 151 Markham, Juraska (bb0265) 2002; 23 Galea, Ormerod, Sampath, Kostaras, Wilkie, Phelps (bb0175) 2000; 37 Atalay, Caner, Can, Cekinmez (bb0010) 2007; 21 Ercan, Inci, Kilinc, Palaoglu, Aypar (bb0125) 2001; 24 Newmark, Newmark (bb0290) 2007; 22 Atif, Sayeed, Ishrat, Stein (bb0015) 2009; 15 Narayanan (10.1016/j.yhbeh.2013.06.009_bb0285) 2004; 35 Hua (10.1016/j.yhbeh.2013.06.009_bb0210) 2012; 61 Carroll (10.1016/j.yhbeh.2013.06.009_bb0060) 2010; 151 Pettus (10.1016/j.yhbeh.2013.06.009_bb0305) 2005; 1049 Brewer (10.1016/j.yhbeh.2013.06.009_bb0040) 2001; 21 Hedden (10.1016/j.yhbeh.2013.06.009_bb0195) 2004; 5 Valtueña (10.1016/j.yhbeh.2013.06.009_bb0395) 2013 Farina (10.1016/j.yhbeh.2013.06.009_bb0145) 2007; 28 Luckhaus (10.1016/j.yhbeh.2013.06.009_bb0250) 2009; 116 Chesler (10.1016/j.yhbeh.2013.06.009_bb0075) 2000; 38 Kuningas (10.1016/j.yhbeh.2013.06.009_bb0230) 2009; 30 Cutler (10.1016/j.yhbeh.2013.06.009_bb0090) 2006; 200 Cai (10.1016/j.yhbeh.2013.06.009_bb0055) 2008; 55 Frick (10.1016/j.yhbeh.2013.06.009_bb0160) 1995; 16 Wali (10.1016/j.yhbeh.2013.06.009_bb0355) 2011; 29 Sun (10.1016/j.yhbeh.2013.06.009_bb0335) 2012; 43 Sharma (10.1016/j.yhbeh.2013.06.009_bb0315) 1994; 27 Fernandes de Abreu (10.1016/j.yhbeh.2013.06.009_bb0155) 2010; 208 Drewes (10.1016/j.yhbeh.2013.06.009_bb0115) 1998; 23 Gallagher (10.1016/j.yhbeh.2013.06.009_bb0180) 1997; 48 Holick (10.1016/j.yhbeh.2013.06.009_bb0200) 2005; 45 Evatt (10.1016/j.yhbeh.2013.06.009_bb0135) 2011; 68 John (10.1016/j.yhbeh.2013.06.009_bb0220) 2003; 9 Atif (10.1016/j.yhbeh.2013.06.009_bb0015) 2009; 15 Vallée (10.1016/j.yhbeh.2013.06.009_bb0345) 2001; 37 Baldi (10.1016/j.yhbeh.2013.06.009_bb0030) 2005; 378 Solomon (10.1016/j.yhbeh.2013.06.009_bb0390) 2011; 6 Stein (10.1016/j.yhbeh.2013.06.009_bb0330) 2011; 3 Ercan (10.1016/j.yhbeh.2013.06.009_bb0125) 2001; 24 Cekic (10.1016/j.yhbeh.2013.06.009_bb0065) 2011; 32 Goss (10.1016/j.yhbeh.2013.06.009_bb0185) 2003; 76 Sarkaki (10.1016/j.yhbeh.2013.06.009_bb0310) 2013; 30 Heaney (10.1016/j.yhbeh.2013.06.009_bb0190) 2004; 80 Annweiler (10.1016/j.yhbeh.2013.06.009_bb0005) 2010; 74 Velíšková (10.1016/j.yhbeh.2013.06.009_bb0400) 2013; 63 Briones (10.1016/j.yhbeh.2013.06.009_bb0370) 2012; 9 Lin (10.1016/j.yhbeh.2013.06.009_bb0240) 2005; 1053 Paulson (10.1016/j.yhbeh.2013.06.009_bb0300) 1994; 108 Ehara (10.1016/j.yhbeh.2013.06.009_bb0120) 2009; 42 Becker (10.1016/j.yhbeh.2013.06.009_bb0035) 2005; 161 Margulies (10.1016/j.yhbeh.2013.06.009_bb0260) 2009; 26 Staffa (10.1016/j.yhbeh.2013.06.009_bb0325) 2012; 29 Balden (10.1016/j.yhbeh.2013.06.009_bb0365) 2012; 153 Kojima (10.1016/j.yhbeh.2013.06.009_bb0225) 2012; 43 McCann (10.1016/j.yhbeh.2013.06.009_bb0275) 2008; 22 Cutler (10.1016/j.yhbeh.2013.06.009_bb0095) 2007; 24 Liu (10.1016/j.yhbeh.2013.06.009_bb0385) 2012; 153 Maas (10.1016/j.yhbeh.2013.06.009_bb0255) 2007; 24 Buell (10.1016/j.yhbeh.2013.06.009_bb0050) 2010; 29 Di Giorgio (10.1016/j.yhbeh.2013.06.009_bb0105) 2007; 10 Galea (10.1016/j.yhbeh.2013.06.009_bb0175) 2000; 37 Eyles (10.1016/j.yhbeh.2013.06.009_bb0140) 2013; 34 Gage (10.1016/j.yhbeh.2013.06.009_bb0170) 1989; 10 Minasyan (10.1016/j.yhbeh.2013.06.009_bb0280) 2007; 104 Newmark (10.1016/j.yhbeh.2013.06.009_bb0290) 2007; 22 Hu (10.1016/j.yhbeh.2013.06.009_bb0205) 2009; 16 Paris (10.1016/j.yhbeh.2013.06.009_bb0295) 2011; 1379 Chisholm (10.1016/j.yhbeh.2013.06.009_bb0085) 2012; 153 Markowska (10.1016/j.yhbeh.2013.06.009_bb0270) 1989; 10 Diamond (10.1016/j.yhbeh.2013.06.009_bb0110) 2005; 183 Felmingham (10.1016/j.yhbeh.2013.06.009_bb0150) 2012; 37 Markham (10.1016/j.yhbeh.2013.06.009_bb0265) 2002; 23 Chisholm (10.1016/j.yhbeh.2013.06.009_bb0375) 2013; 1514C Atalay (10.1016/j.yhbeh.2013.06.009_bb0010) 2007; 21 Hua (10.1016/j.yhbeh.2013.06.009_bb0215) 2011; 8 Deluca (10.1016/j.yhbeh.2013.06.009_bb0380) 2013 Frick (10.1016/j.yhbeh.2013.06.009_bb0165) 2000; 95 Evatt (10.1016/j.yhbeh.2013.06.009_bb0130) 2008; 65 Chatterjee (10.1016/j.yhbeh.2013.06.009_bb0070) 2001; 475 Atif (10.1016/j.yhbeh.2013.06.009_bb0360) 2013; 67 18579197 - Mol Aspects Med. 2008 Dec;29(6):415-22 17276138 - Trends Immunol. 2007 Mar;28(3):138-45 17230473 - Mov Disord. 2007 Mar 15;22(4):461-8 11744095 - Brain Res Brain Res Rev. 2001 Nov;37(1-3):301-12 2682316 - Neurobiol Aging. 1989 Jul-Aug;10(4):347-52 20410196 - Endocrinology. 2010 Jun;151(6):2713-22 22534403 - Psychoneuroendocrinology. 2012 Nov;37(11):1896-900 11150325 - J Neurosci. 2001 Jan 1;21(1):98-108 18056830 - FASEB J. 2008 Apr;22(4):982-1001 23336971 - Neuropathol Appl Neurobiol. 2013 Aug;39(5):458-84 19468818 - J Neural Transm (Vienna). 2009 Jul;116(7):905-11 17435754 - Nat Neurosci. 2007 May;10(5):608-14 11485234 - Neurosurg Rev. 2001 Jul;24(2-3):127-30 23098125 - J Neuroinflammation. 2012;9:244 19482377 - Neurobiol Aging. 2011 May;32(5):864-74 21851230 - J Neurotrauma. 2013 Jan 1;30(1):47-54 15992330 - Med J Aust. 2005 Jul 4;183(1):10-2 19794127 - Neurology. 2010 Jan 5;74(1):27-32 17482806 - J Steroid Biochem Mol Biol. 2007 May;104(3-5):274-80 15957143 - Am J Kidney Dis. 2005 Jun;45(6):1119-21 15932748 - Brain Res. 2005 Jul 5;1049(1):112-9 21044614 - Brain Res. 2011 Mar 16;1379:149-63 22442173 - Stroke. 2012 Jun;43(6):1470-7 10619486 - Neuroscience. 2000;95(1):293-307 11295155 - Mutat Res. 2001 Apr 18;475(1-2):69-87 15922058 - Behav Brain Res. 2005 Jun 20;161(2):306-12 14735112 - Nat Rev Neurosci. 2004 Feb;5(2):87-96 7917055 - Behav Neurosci. 1994 Jun;108(3):624-35 9757832 - Trends Biochem Sci. 1998 Aug;23(8):307-11 17714831 - Neurobiol Aging. 2009 Mar;30(3):466-73 18572204 - Neuropharmacology. 2008 Aug;55(2):127-38 16179538 - Ann N Y Acad Sci. 2005 Aug;1053:319-29 21335669 - Restor Neurol Neurosci. 2011;29(1):61-71 12580336 - Neuroscientist. 2003 Feb;9(1):10-22 2569170 - Neurobiol Aging. 1989 Jan-Feb;10(1):31-43 20126570 - Acta Histochem Cytochem. 2009 Dec 29;42(6):171-9 15585791 - Am J Clin Nutr. 2004 Dec;80(6 Suppl):1706S-9S 22216257 - PLoS One. 2011;6(12):e29354 19331514 - J Neurotrauma. 2009 Jun;26(6):925-39 19355896 - Curr Med Chem. 2009;16(11):1418-25 21703565 - PM R. 2011 Jun;3(6 Suppl 1):S100-10 16797538 - Exp Neurol. 2006 Aug;200(2):378-85 22504305 - Horm Behav. 2013 Feb;63(2):267-77 15781154 - Neurosci Lett. 2005 Apr 22;378(3):176-80 17375987 - J Neurotrauma. 2007 Feb;24(2):232-8 18852350 - Arch Neurol. 2008 Oct;65(10):1348-52 22796576 - Front Neuroendocrinol. 2013 Jan;34(1):47-64 23657707 - QJM. 2013 Sep;106(9):809-21 9046563 - Annu Rev Psychol. 1997;48:339-70 22408173 - Endocrinology. 2012 May;153(5):2420-35 17612919 - Br J Neurosurg. 2007 Jun;21(3):281-7 14592674 - Pharmacol Biochem Behav. 2003 Sep;76(2):231-42 22903611 - Endocrinology. 2012 Oct;153(10):4874-82 12009507 - Neurobiol Aging. 2002 Jul-Aug;23(4):579-88 22570859 - Horm Behav. 2012 Apr;61(4):642-51 17892409 - J Neurotrauma. 2007 Sep;24(9):1475-86 11104641 - Horm Behav. 2000 Dec;38(4):234-42 21403017 - Arch Neurol. 2011 Mar;68(3):314-9 19603099 - Mol Med. 2009 Sep-Oct;15(9-10):328-36 23154302 - Neuropharmacology. 2013 Apr;67:78-87 15207749 - Bone. 2004 Jul;35(1):134-43 23030803 - J Neurotrauma. 2012 Nov 20;29(17):2716-21 20079764 - Behav Brain Res. 2010 Apr 2;208(2):603-8 10712861 - Horm Behav. 2000 Feb;37(1):86-95 22627988 - Stroke. 2012 Aug;43(8):2163-7 23419893 - Brain Res. 2013 Jun 13;1514:40-9 21549006 - J Neuroinflammation. 2011;8:42 8020109 - Cell Motil Cytoskeleton. 1994;27(3):234-47 22635678 - Endocrinology. 2012 Aug;153(8):3747-57 7777133 - Neurobiol Aging. 1995 Mar-Apr;16(2):149-60 |
| References_xml | – volume: 200 start-page: 378 year: 2006 end-page: 385 ident: bb0090 article-title: Tapered progesterone withdrawal promotes long-term recovery following brain trauma publication-title: Exp. Neurol. – volume: 37 start-page: 1896 year: 2012 end-page: 1900 ident: bb0150 article-title: The impact of progesterone on memory consolidation of threatening images in women publication-title: Psychoneuroendocrinology – volume: 161 start-page: 306 year: 2005 end-page: 312 ident: bb0035 article-title: Transient prenatal vitamin D deficiency is associated with subtle alterations in learning and memory functions in adult rats publication-title: Behav. Brain Res. – volume: 1053 start-page: 319 year: 2005 end-page: 329 ident: bb0240 article-title: Antioxidative effect of vitamin D3 on zincinduced oxidative stress in CNS publication-title: Ann. N. Y. Acad. Sci. – volume: 63 start-page: 267 year: 2013 end-page: 277 ident: bb0400 article-title: Sex and hormonal influences on seizures and epilepsy publication-title: Horm. Behav. – volume: 95 start-page: 293 year: 2000 end-page: 307 ident: bb0165 article-title: Reference memory, anxiety and estrous cyclicity in C57BL/6NIA mice are affected by age and sex publication-title: Neuroscience – volume: 24 start-page: 127 year: 2001 end-page: 130 ident: bb0125 article-title: Nimodipine attenuates lipid peroxidation during the acute phase of head trauma in rats publication-title: Neurosurg. Rev. – volume: 30 start-page: 47 year: 2013 end-page: 54 ident: bb0310 article-title: Time- and dose-dependent neuroprotective effects of sex steroid hormones on inflammatory cytokines after a traumatic brain injury publication-title: J. Neurotrauma – year: 2013 ident: bb0395 article-title: Cardiorespiratory fitness in males, and upper limbs muscular strength in females, are positively related with 25-hydroxyvitamin D plasma concentrations in European adolescents: the HELENA study publication-title: QJM – volume: 42 start-page: 171 year: 2009 end-page: 179 ident: bb0120 article-title: Application of Fluoro-Jade C in acute and chronic neurodegeneration models: utilities and staining differences publication-title: Acta Histochem. Cytochem. – volume: 475 start-page: 69 year: 2001 end-page: 87 ident: bb0070 article-title: Vitamin D and genomic stability publication-title: Mutat. Res. – volume: 38 start-page: 234 year: 2000 end-page: 242 ident: bb0075 article-title: Acute administration of estrogen and progesterone impairs the acquisition of the spatial Morris water maze in ovariectomized rats publication-title: Horm. Behav. – volume: 16 start-page: 149 year: 1995 end-page: 160 ident: bb0160 article-title: Age-related spatial reference and working memory deficits assessed in the water maze publication-title: Neurobiol. Aging – volume: 153 start-page: 2420 year: 2012 end-page: 2435 ident: bb0365 article-title: Vitamin D deficiency exacerbates experimental stroke injury and dysregulates ischemia-induced inflammation in adult rats publication-title: Endocrinology – volume: 76 start-page: 231 year: 2003 end-page: 242 ident: bb0185 article-title: Behavioral effects and anatomic correlates after brain injury: a progesterone dose-response study publication-title: Pharmacol. Biochem. Behav. – volume: 21 start-page: 281 year: 2007 end-page: 287 ident: bb0010 article-title: Attenuation of microtubule associated protein-2 degradation after mild head injury by mexiletine and calpain-2 inhibitor publication-title: Br. J. Neurosurg. – volume: 208 start-page: 603 year: 2010 end-page: 608 ident: bb0155 article-title: Developmental vitamin D deficiency alters learning in C57Bl/6J mice publication-title: Behav. Brain Res. – volume: 16 start-page: 1418 year: 2009 end-page: 1425 ident: bb0205 article-title: Exogenous progesterone: a potential therapeutic candidate in CNS injury and neurodegeneration publication-title: Curr. Med. Chem. – volume: 29 start-page: 2716 year: 2012 end-page: 2721 ident: bb0325 article-title: Cerebellar gene expression following human traumatic brain injury publication-title: J. Neurotrauma – volume: 10 start-page: 608 year: 2007 end-page: 614 ident: bb0105 article-title: Non-cell autonomous effect of glia on motor neurons in an embryonic stem cellbased ALS model publication-title: Nat. Neurosci. – volume: 378 start-page: 176 year: 2005 end-page: 180 ident: bb0030 article-title: Spatial navigation in the Morris water maze: working and long lasting reference memories publication-title: Neurosci. Lett. – volume: 10 start-page: 31 year: 1989 end-page: 43 ident: bb0270 article-title: Individual differences in aging: behavioral and neurobiological correlates publication-title: Neurobiol. Aging – volume: 153 start-page: 3747 year: 2012 end-page: 3757 ident: bb0385 article-title: Progesterone receptors: a key for neuroprotection in experimental stroke publication-title: Endocrinology – year: 2013 ident: bb0380 article-title: The role of vitamin D in nervous system health and disease publication-title: Neuropathol. Appl. Neurobiol – volume: 29 start-page: 61 year: 2011 end-page: 71 ident: bb0355 article-title: Improved behavioral outcomes after progesterone administration in aged male rats with traumatic brain injury publication-title: Restor. Neurol. Neurosci. – volume: 68 start-page: 314 year: 2011 end-page: 319 ident: bb0135 article-title: High prevalence of hypovitaminosis D status in patients with early Parkinson disease publication-title: Arch. Neurol. – volume: 10 start-page: 347 year: 1989 end-page: 352 ident: bb0170 article-title: Age-related impairments in spatial memory are independent of those in sensorimotor skills publication-title: Neurobiol. Aging – volume: 23 start-page: 579 year: 2002 end-page: 588 ident: bb0265 article-title: Aging and sex influence the anatomy of the rat anterior cingulate cortex publication-title: Neurobiol. Aging – volume: 1379 start-page: 149 year: 2011 end-page: 163 ident: bb0295 article-title: Cognitive performance of middle-aged female rats is influenced by capacity to metabolize progesterone in the prefrontal cortex and hippocampus publication-title: Brain Res. – volume: 108 start-page: 624 year: 1994 end-page: 635 ident: bb0300 article-title: Relationship between circadian changes in spontaneous motor activity and dorsal versus ventral striatal dopamine neurotransmission assessed with on-line microdialysis publication-title: Behav. Neurosci. – volume: 1049 start-page: 112 year: 2005 end-page: 119 ident: bb0305 article-title: Progesterone treatment inhibits the inflammatory agents that accompany traumatic brain injury publication-title: Brain Res. – volume: 6 start-page: e29354 year: 2011 ident: bb0390 article-title: Vitamin D3 deficiency differentially affects functional and disease outcomes in the G93A mouse model of amyotrophic lateral sclerosis publication-title: PLoS One – volume: 80 start-page: 1706S year: 2004 end-page: 1709S ident: bb0190 article-title: Functional indices of vitamin D status and ramifications of vitamin D deficiency publication-title: Am. J. Clin. Nutr. – volume: 43 start-page: 2163 year: 2012 end-page: 2167 ident: bb0225 article-title: Low dietary vitamin D predicts 34-year incident stroke: the Honolulu Heart Program publication-title: Stroke – volume: 22 start-page: 982 year: 2008 end-page: 1001 ident: bb0275 article-title: Is there convincing biological or behavioral evidence linking vitamin D deficiency to brain dysfunction? publication-title: FASEB J. – volume: 151 start-page: 2713 year: 2010 end-page: 2722 ident: bb0060 article-title: Continuous and cyclic progesterone differentially interact with estradiol in the regulation of Alzheimer-like pathology in female 3xTransgenic-Alzheimer's disease mice publication-title: Endocrinology – volume: 65 start-page: 1348 year: 2008 end-page: 1352 ident: bb0130 article-title: Prevalence of vitamin D insufficiency in patients with Parkinson disease and Alzheimer disease publication-title: Arch. Neurol. – volume: 3 start-page: S100 year: 2011 end-page: S110 ident: bb0330 article-title: Progesterone and vitamin d hormone as a biologic treatment of traumatic brain injury in the aged publication-title: PM R – volume: 27 start-page: 234 year: 1994 end-page: 247 ident: bb0315 article-title: Antisense MAP-2 oligonucleotides induce changes in microtubule assembly and neuritic elongation in pre-existing neurites of rat cortical neurons publication-title: Cell Motil. Cytoskeleton – volume: 183 start-page: 10 year: 2005 end-page: 12 ident: bb0110 article-title: Annual intramuscular injection of a megadose of cholecalciferol for treatment of vitamin D deficiency: efficacy and safety data publication-title: Med. J. – volume: 153 start-page: 4874 year: 2012 end-page: 4882 ident: bb0085 article-title: The effects of long-term treatment with estradiol and medroxyprogesterone acetate on tyrosine hydroxylase fibers and neuron number in the medial prefrontal cortex of aged female rats publication-title: Endocrinology – volume: 45 start-page: 1119 year: 2005 end-page: 1121 ident: bb0200 article-title: Vitamin D deficiency in CKD: why should we care? publication-title: Am. J. Kidney Dis. – volume: 8 start-page: 42 year: 2011 ident: bb0215 article-title: Genomic profile of Toll-like receptor pathways in traumatically brain-injured mice: effect of exogenous progesterone publication-title: J. Neuroinflammation – volume: 34 start-page: 47 year: 2013 end-page: 64 ident: bb0140 article-title: Vitamin D, effects on brain development, adult brain function and the links between low levels of vitamin D and neuropsychiatric disease publication-title: Front. Neuroendocrinol. – volume: 55 start-page: 127 year: 2008 end-page: 138 ident: bb0055 article-title: Two different molecular mechanisms underlying progesterone neuroprotection against ischemic brain damage publication-title: Neuropharmacology – volume: 37 start-page: 301 year: 2001 end-page: 312 ident: bb0345 article-title: Role of pregnenolone, dehydroepiandrosterone and their sulfate esters on learning and memory in cognitive aging publication-title: Brain Res. Brain Res. Rev. – volume: 61 start-page: 642 year: 2012 end-page: 651 ident: bb0210 article-title: Progesterone and low-dose vitamin D hormone treatment enhances sparing of memory following traumatic brain injury publication-title: Horm. Behav. – volume: 30 start-page: 466 year: 2009 end-page: 473 ident: bb0230 article-title: VDR gene variants associate with cognitive function and depressive symptoms in old age publication-title: Neurobiol. Aging – volume: 29 start-page: 415 year: 2010 end-page: 422 ident: bb0050 article-title: Vitamin D and neurocognitive dysfunction: preventing “D”ecline? publication-title: Mol. Aspects Med. – volume: 22 start-page: 461 year: 2007 end-page: 468 ident: bb0290 article-title: Vitamin D and Parkinson's disease—a hypothesis publication-title: Mov. Disord. – volume: 24 start-page: 232 year: 2007 end-page: 238 ident: bb0255 article-title: Prognosis and clinical trial design in traumatic brain injury: the Impact study publication-title: J. Neurotrauma – volume: 21 start-page: 98 year: 2001 end-page: 108 ident: bb0040 article-title: Vitamin D hormone confers neuroprotection in parallel with downregulation of L-type calcium channel expression in hippocampal neurons publication-title: J. Neurosci. – volume: 116 start-page: 905 year: 2009 end-page: 911 ident: bb0250 article-title: Blood biomarkers of osteoporosis in mild cognitive impairment and Alzheimer's disease publication-title: J. Neural Transm. – volume: 9 start-page: 244 year: 2012 ident: bb0370 article-title: Vitamin D mitigates age-related cognitive decline through the modulation of pro-inflammatory state and decrease in amyloid burden publication-title: J. Neuroinflammation – volume: 32 start-page: 864 year: 2011 end-page: 874 ident: bb0065 article-title: Vitamin D deficiency reduces the benefits of progesterone treatment after brain injury in aged rats publication-title: Neurobiol. Aging – volume: 37 start-page: 86 year: 2000 end-page: 95 ident: bb0175 article-title: Spatial working memory and hippocampal size across pregnancy in rats publication-title: Horm. Behav. – volume: 15 start-page: 328 year: 2009 end-page: 336 ident: bb0015 article-title: Progesterone with vitamin D affords better neuroprotection against excitotoxicity in cultured cortical neurons than progesterone alone publication-title: Mol. Med. – volume: 9 start-page: 10 year: 2003 end-page: 22 ident: bb0220 article-title: Cytokines: powerful regulators of glial cell activation publication-title: Neuroscientist – volume: 74 start-page: 27 year: 2010 end-page: 32 ident: bb0005 article-title: Association of vitamin D deficiency with cognitive impairment in older women: cross-sectional study publication-title: Neurology – volume: 104 start-page: 274 year: 2007 end-page: 280 ident: bb0280 article-title: Neophobia, sensory and cognitive functions, and hedonic responses in vitamin D receptor mutant mice publication-title: J. Steroid Biochem. Mol. Biol. – volume: 5 start-page: 87 year: 2004 end-page: 96 ident: bb0195 article-title: Insights into the ageing mind: a view from cognitive neuroscience publication-title: Nat. Rev. Neurosci. – volume: 43 start-page: 1470 year: 2012 end-page: 1477 ident: bb0335 article-title: 25-Hydroxyvitamin D levels and the risk of stroke: a prospective study and meta-analysis publication-title: Stroke – volume: 23 start-page: 307 year: 1998 end-page: 311 ident: bb0115 article-title: MAPs, MARKs and microtubule dynamics publication-title: Trends Biochem. Sci. – volume: 35 start-page: 134 year: 2004 end-page: 143 ident: bb0285 article-title: Differential skeletal responses of hindlimb unloaded rats on a vitamin D-deficient diet to 1,25-dihydroxyvitamin D3 and its analog, seocalcitol (EB1089) publication-title: Bone – volume: 26 start-page: 925 year: 2009 end-page: 939 ident: bb0260 article-title: Combination therapies for traumatic brain injury: prospective considerations publication-title: J. Neurotrauma – volume: 67 start-page: 78 year: 2013 end-page: 87 ident: bb0360 article-title: Combination treatment with progesterone and vitamin D hormone is more effective than monotherapy in ischemic stroke: the role of BDNF/TrkB/Erk1/2 signaling in neuroprotection publication-title: Neuropharmacology – volume: 24 start-page: 1475 year: 2007 end-page: 1486 ident: bb0095 article-title: Progesterone improves acute recovery after traumatic brain injury in the aged rat publication-title: J. Neurotrauma – volume: 1514C start-page: 40 year: 2013 end-page: 49 ident: bb0375 article-title: Factors influencing the cognitive and neural effects of hormone treatment during aging in a rodent model publication-title: Brain Res. – volume: 28 start-page: 138 year: 2007 end-page: 145 ident: bb0145 article-title: Astrocytes are active players in cerebral innate immunity publication-title: Trends Immunol. – volume: 48 start-page: 339 year: 1997 end-page: 370 ident: bb0180 article-title: The use of animal models to study the effects of aging on cognition publication-title: Annu. Rev. Psychol. – volume: 5 start-page: 87 year: 2004 ident: 10.1016/j.yhbeh.2013.06.009_bb0195 article-title: Insights into the ageing mind: a view from cognitive neuroscience publication-title: Nat. Rev. Neurosci. doi: 10.1038/nrn1323 – volume: 9 start-page: 244 issue: 1 year: 2012 ident: 10.1016/j.yhbeh.2013.06.009_bb0370 article-title: Vitamin D mitigates age-related cognitive decline through the modulation of pro-inflammatory state and decrease in amyloid burden publication-title: J. Neuroinflammation doi: 10.1186/1742-2094-9-244 – volume: 21 start-page: 98 year: 2001 ident: 10.1016/j.yhbeh.2013.06.009_bb0040 article-title: Vitamin D hormone confers neuroprotection in parallel with downregulation of L-type calcium channel expression in hippocampal neurons publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.21-01-00098.2001 – volume: 42 start-page: 171 issue: 6 year: 2009 ident: 10.1016/j.yhbeh.2013.06.009_bb0120 article-title: Application of Fluoro-Jade C in acute and chronic neurodegeneration models: utilities and staining differences publication-title: Acta Histochem. Cytochem. doi: 10.1267/ahc.09018 – volume: 475 start-page: 69 year: 2001 ident: 10.1016/j.yhbeh.2013.06.009_bb0070 article-title: Vitamin D and genomic stability publication-title: Mutat. Res. doi: 10.1016/S0027-5107(01)00080-X – volume: 24 start-page: 1475 issue: 9 year: 2007 ident: 10.1016/j.yhbeh.2013.06.009_bb0095 article-title: Progesterone improves acute recovery after traumatic brain injury in the aged rat publication-title: J. Neurotrauma doi: 10.1089/neu.2007.0294 – volume: 9 start-page: 10 issue: 1 year: 2003 ident: 10.1016/j.yhbeh.2013.06.009_bb0220 article-title: Cytokines: powerful regulators of glial cell activation publication-title: Neuroscientist doi: 10.1177/1073858402239587 – volume: 10 start-page: 347 issue: 4 year: 1989 ident: 10.1016/j.yhbeh.2013.06.009_bb0170 article-title: Age-related impairments in spatial memory are independent of those in sensorimotor skills publication-title: Neurobiol. Aging doi: 10.1016/0197-4580(89)90047-X – volume: 1514C start-page: 40 year: 2013 ident: 10.1016/j.yhbeh.2013.06.009_bb0375 article-title: Factors influencing the cognitive and neural effects of hormone treatment during aging in a rodent model publication-title: Brain Res. doi: 10.1016/j.brainres.2013.02.020 – volume: 48 start-page: 339 year: 1997 ident: 10.1016/j.yhbeh.2013.06.009_bb0180 article-title: The use of animal models to study the effects of aging on cognition publication-title: Annu. Rev. Psychol. doi: 10.1146/annurev.psych.48.1.339 – volume: 1379 start-page: 149 year: 2011 ident: 10.1016/j.yhbeh.2013.06.009_bb0295 article-title: Cognitive performance of middle-aged female rats is influenced by capacity to metabolize progesterone in the prefrontal cortex and hippocampus publication-title: Brain Res. doi: 10.1016/j.brainres.2010.10.099 – volume: 43 start-page: 1470 issue: 6 year: 2012 ident: 10.1016/j.yhbeh.2013.06.009_bb0335 article-title: 25-Hydroxyvitamin D levels and the risk of stroke: a prospective study and meta-analysis publication-title: Stroke doi: 10.1161/STROKEAHA.111.636910 – volume: 21 start-page: 281 issue: 3 year: 2007 ident: 10.1016/j.yhbeh.2013.06.009_bb0010 article-title: Attenuation of microtubule associated protein-2 degradation after mild head injury by mexiletine and calpain-2 inhibitor publication-title: Br. J. Neurosurg. doi: 10.1080/02688690701364781 – year: 2013 ident: 10.1016/j.yhbeh.2013.06.009_bb0380 article-title: The role of vitamin D in nervous system health and disease publication-title: Neuropathol. Appl. Neurobiol doi: 10.1111/nan.12020 – volume: 23 start-page: 579 year: 2002 ident: 10.1016/j.yhbeh.2013.06.009_bb0265 article-title: Aging and sex influence the anatomy of the rat anterior cingulate cortex publication-title: Neurobiol. Aging doi: 10.1016/S0197-4580(02)00004-0 – volume: 104 start-page: 274 issue: 3–5 year: 2007 ident: 10.1016/j.yhbeh.2013.06.009_bb0280 article-title: Neophobia, sensory and cognitive functions, and hedonic responses in vitamin D receptor mutant mice publication-title: J. Steroid Biochem. Mol. Biol. doi: 10.1016/j.jsbmb.2007.03.032 – volume: 32 start-page: 864 issue: 5 year: 2011 ident: 10.1016/j.yhbeh.2013.06.009_bb0065 article-title: Vitamin D deficiency reduces the benefits of progesterone treatment after brain injury in aged rats publication-title: Neurobiol. Aging doi: 10.1016/j.neurobiolaging.2009.04.017 – volume: 95 start-page: 293 issue: 1 year: 2000 ident: 10.1016/j.yhbeh.2013.06.009_bb0165 article-title: Reference memory, anxiety and estrous cyclicity in C57BL/6NIA mice are affected by age and sex publication-title: Neuroscience doi: 10.1016/S0306-4522(99)00418-2 – volume: 37 start-page: 301 issue: 1–3 year: 2001 ident: 10.1016/j.yhbeh.2013.06.009_bb0345 article-title: Role of pregnenolone, dehydroepiandrosterone and their sulfate esters on learning and memory in cognitive aging publication-title: Brain Res. Brain Res. Rev. doi: 10.1016/S0165-0173(01)00135-7 – volume: 63 start-page: 267 issue: 2 year: 2013 ident: 10.1016/j.yhbeh.2013.06.009_bb0400 article-title: Sex and hormonal influences on seizures and epilepsy publication-title: Horm. Behav. doi: 10.1016/j.yhbeh.2012.03.018 – volume: 30 start-page: 47 issue: 1 year: 2013 ident: 10.1016/j.yhbeh.2013.06.009_bb0310 article-title: Time- and dose-dependent neuroprotective effects of sex steroid hormones on inflammatory cytokines after a traumatic brain injury publication-title: J. Neurotrauma doi: 10.1089/neu.2010.1686 – volume: 161 start-page: 306 issue: 2 year: 2005 ident: 10.1016/j.yhbeh.2013.06.009_bb0035 article-title: Transient prenatal vitamin D deficiency is associated with subtle alterations in learning and memory functions in adult rats publication-title: Behav. Brain Res. doi: 10.1016/j.bbr.2005.02.015 – volume: 68 start-page: 314 issue: 3 year: 2011 ident: 10.1016/j.yhbeh.2013.06.009_bb0135 article-title: High prevalence of hypovitaminosis D status in patients with early Parkinson disease publication-title: Arch. Neurol. doi: 10.1001/archneurol.2011.30 – volume: 22 start-page: 982 issue: 4 year: 2008 ident: 10.1016/j.yhbeh.2013.06.009_bb0275 article-title: Is there convincing biological or behavioral evidence linking vitamin D deficiency to brain dysfunction? publication-title: FASEB J. doi: 10.1096/fj.07-9326rev – volume: 200 start-page: 378 issue: 2 year: 2006 ident: 10.1016/j.yhbeh.2013.06.009_bb0090 article-title: Tapered progesterone withdrawal promotes long-term recovery following brain trauma publication-title: Exp. Neurol. doi: 10.1016/j.expneurol.2006.02.137 – volume: 28 start-page: 138 issue: 3 year: 2007 ident: 10.1016/j.yhbeh.2013.06.009_bb0145 article-title: Astrocytes are active players in cerebral innate immunity publication-title: Trends Immunol. doi: 10.1016/j.it.2007.01.005 – volume: 24 start-page: 127 year: 2001 ident: 10.1016/j.yhbeh.2013.06.009_bb0125 article-title: Nimodipine attenuates lipid peroxidation during the acute phase of head trauma in rats publication-title: Neurosurg. Rev. doi: 10.1007/PL00012396 – volume: 10 start-page: 31 issue: 1 year: 1989 ident: 10.1016/j.yhbeh.2013.06.009_bb0270 article-title: Individual differences in aging: behavioral and neurobiological correlates publication-title: Neurobiol. Aging doi: 10.1016/S0197-4580(89)80008-9 – volume: 1053 start-page: 319 year: 2005 ident: 10.1016/j.yhbeh.2013.06.009_bb0240 article-title: Antioxidative effect of vitamin D3 on zincinduced oxidative stress in CNS publication-title: Ann. N. Y. Acad. Sci. doi: 10.1196/annals.1344.028 – volume: 3 start-page: S100 issue: 6 Suppl. 1 year: 2011 ident: 10.1016/j.yhbeh.2013.06.009_bb0330 article-title: Progesterone and vitamin d hormone as a biologic treatment of traumatic brain injury in the aged publication-title: PM R doi: 10.1016/j.pmrj.2011.03.010 – volume: 10 start-page: 608 issue: 5 year: 2007 ident: 10.1016/j.yhbeh.2013.06.009_bb0105 article-title: Non-cell autonomous effect of glia on motor neurons in an embryonic stem cellbased ALS model publication-title: Nat. Neurosci. doi: 10.1038/nn1885 – volume: 116 start-page: 905 issue: 7 year: 2009 ident: 10.1016/j.yhbeh.2013.06.009_bb0250 article-title: Blood biomarkers of osteoporosis in mild cognitive impairment and Alzheimer's disease publication-title: J. Neural Transm. doi: 10.1007/s00702-009-0241-x – volume: 16 start-page: 149 issue: 2 year: 1995 ident: 10.1016/j.yhbeh.2013.06.009_bb0160 article-title: Age-related spatial reference and working memory deficits assessed in the water maze publication-title: Neurobiol. Aging doi: 10.1016/0197-4580(94)00155-3 – volume: 45 start-page: 1119 issue: 6 year: 2005 ident: 10.1016/j.yhbeh.2013.06.009_bb0200 article-title: Vitamin D deficiency in CKD: why should we care? publication-title: Am. J. Kidney Dis. doi: 10.1053/j.ajkd.2005.04.015 – volume: 43 start-page: 2163 issue: 8 year: 2012 ident: 10.1016/j.yhbeh.2013.06.009_bb0225 article-title: Low dietary vitamin D predicts 34-year incident stroke: the Honolulu Heart Program publication-title: Stroke doi: 10.1161/STROKEAHA.112.651752 – volume: 30 start-page: 466 issue: 3 year: 2009 ident: 10.1016/j.yhbeh.2013.06.009_bb0230 article-title: VDR gene variants associate with cognitive function and depressive symptoms in old age publication-title: Neurobiol. Aging doi: 10.1016/j.neurobiolaging.2007.07.001 – year: 2013 ident: 10.1016/j.yhbeh.2013.06.009_bb0395 article-title: Cardiorespiratory fitness in males, and upper limbs muscular strength in females, are positively related with 25-hydroxyvitamin D plasma concentrations in European adolescents: the HELENA study publication-title: QJM – volume: 61 start-page: 642 issue: 4 year: 2012 ident: 10.1016/j.yhbeh.2013.06.009_bb0210 article-title: Progesterone and low-dose vitamin D hormone treatment enhances sparing of memory following traumatic brain injury publication-title: Horm. Behav. doi: 10.1016/j.yhbeh.2012.02.017 – volume: 27 start-page: 234 year: 1994 ident: 10.1016/j.yhbeh.2013.06.009_bb0315 article-title: Antisense MAP-2 oligonucleotides induce changes in microtubule assembly and neuritic elongation in pre-existing neurites of rat cortical neurons publication-title: Cell Motil. Cytoskeleton doi: 10.1002/cm.970270305 – volume: 34 start-page: 47 issue: 1 year: 2013 ident: 10.1016/j.yhbeh.2013.06.009_bb0140 article-title: Vitamin D, effects on brain development, adult brain function and the links between low levels of vitamin D and neuropsychiatric disease publication-title: Front. Neuroendocrinol. doi: 10.1016/j.yfrne.2012.07.001 – volume: 26 start-page: 925 issue: 6 year: 2009 ident: 10.1016/j.yhbeh.2013.06.009_bb0260 article-title: Combination therapies for traumatic brain injury: prospective considerations publication-title: J. Neurotrauma doi: 10.1089/neu.2008.0794 – volume: 23 start-page: 307 issue: 8 year: 1998 ident: 10.1016/j.yhbeh.2013.06.009_bb0115 article-title: MAPs, MARKs and microtubule dynamics publication-title: Trends Biochem. Sci. doi: 10.1016/S0968-0004(98)01245-6 – volume: 65 start-page: 1348 issue: 10 year: 2008 ident: 10.1016/j.yhbeh.2013.06.009_bb0130 article-title: Prevalence of vitamin D insufficiency in patients with Parkinson disease and Alzheimer disease publication-title: Arch. Neurol. doi: 10.1001/archneur.65.10.1348 – volume: 29 start-page: 61 issue: 1 year: 2011 ident: 10.1016/j.yhbeh.2013.06.009_bb0355 article-title: Improved behavioral outcomes after progesterone administration in aged male rats with traumatic brain injury publication-title: Restor. Neurol. Neurosci. – volume: 74 start-page: 27 year: 2010 ident: 10.1016/j.yhbeh.2013.06.009_bb0005 article-title: Association of vitamin D deficiency with cognitive impairment in older women: cross-sectional study publication-title: Neurology doi: 10.1212/WNL.0b013e3181beecd3 – volume: 22 start-page: 461 issue: 4 year: 2007 ident: 10.1016/j.yhbeh.2013.06.009_bb0290 article-title: Vitamin D and Parkinson's disease—a hypothesis publication-title: Mov. Disord. doi: 10.1002/mds.21317 – volume: 153 start-page: 2420 issue: 5 year: 2012 ident: 10.1016/j.yhbeh.2013.06.009_bb0365 article-title: Vitamin D deficiency exacerbates experimental stroke injury and dysregulates ischemia-induced inflammation in adult rats publication-title: Endocrinology doi: 10.1210/en.2011-1783 – volume: 378 start-page: 176 issue: 3 year: 2005 ident: 10.1016/j.yhbeh.2013.06.009_bb0030 article-title: Spatial navigation in the Morris water maze: working and long lasting reference memories publication-title: Neurosci. Lett. doi: 10.1016/j.neulet.2004.12.029 – volume: 37 start-page: 86 issue: 1 year: 2000 ident: 10.1016/j.yhbeh.2013.06.009_bb0175 article-title: Spatial working memory and hippocampal size across pregnancy in rats publication-title: Horm. Behav. doi: 10.1006/hbeh.1999.1560 – volume: 208 start-page: 603 issue: 2 year: 2010 ident: 10.1016/j.yhbeh.2013.06.009_bb0155 article-title: Developmental vitamin D deficiency alters learning in C57Bl/6J mice publication-title: Behav. Brain Res. doi: 10.1016/j.bbr.2010.01.005 – volume: 76 start-page: 231 issue: 2 year: 2003 ident: 10.1016/j.yhbeh.2013.06.009_bb0185 article-title: Behavioral effects and anatomic correlates after brain injury: a progesterone dose-response study publication-title: Pharmacol. Biochem. Behav. doi: 10.1016/j.pbb.2003.07.003 – volume: 29 start-page: 415 issue: 6 year: 2010 ident: 10.1016/j.yhbeh.2013.06.009_bb0050 article-title: Vitamin D and neurocognitive dysfunction: preventing “D”ecline? publication-title: Mol. Aspects Med. doi: 10.1016/j.mam.2008.05.001 – volume: 16 start-page: 1418 year: 2009 ident: 10.1016/j.yhbeh.2013.06.009_bb0205 article-title: Exogenous progesterone: a potential therapeutic candidate in CNS injury and neurodegeneration publication-title: Curr. Med. Chem. doi: 10.2174/092986709787846523 – volume: 55 start-page: 127 year: 2008 ident: 10.1016/j.yhbeh.2013.06.009_bb0055 article-title: Two different molecular mechanisms underlying progesterone neuroprotection against ischemic brain damage publication-title: Neuropharmacology doi: 10.1016/j.neuropharm.2008.04.023 – volume: 183 start-page: 10 issue: 1 year: 2005 ident: 10.1016/j.yhbeh.2013.06.009_bb0110 article-title: Annual intramuscular injection of a megadose of cholecalciferol for treatment of vitamin D deficiency: efficacy and safety data publication-title: Med. J. – volume: 15 start-page: 328 issue: 9–10 year: 2009 ident: 10.1016/j.yhbeh.2013.06.009_bb0015 article-title: Progesterone with vitamin D affords better neuroprotection against excitotoxicity in cultured cortical neurons than progesterone alone publication-title: Mol. Med. doi: 10.2119/molmed.2009.00016 – volume: 151 start-page: 2713 issue: 6 year: 2010 ident: 10.1016/j.yhbeh.2013.06.009_bb0060 article-title: Continuous and cyclic progesterone differentially interact with estradiol in the regulation of Alzheimer-like pathology in female 3xTransgenic-Alzheimer's disease mice publication-title: Endocrinology doi: 10.1210/en.2009-1487 – volume: 153 start-page: 4874 issue: 10 year: 2012 ident: 10.1016/j.yhbeh.2013.06.009_bb0085 article-title: The effects of long-term treatment with estradiol and medroxyprogesterone acetate on tyrosine hydroxylase fibers and neuron number in the medial prefrontal cortex of aged female rats publication-title: Endocrinology doi: 10.1210/en.2012-1412 – volume: 29 start-page: 2716 issue: 17 year: 2012 ident: 10.1016/j.yhbeh.2013.06.009_bb0325 article-title: Cerebellar gene expression following human traumatic brain injury publication-title: J. Neurotrauma doi: 10.1089/neu.2011.2246 – volume: 1049 start-page: 112 issue: 1 year: 2005 ident: 10.1016/j.yhbeh.2013.06.009_bb0305 article-title: Progesterone treatment inhibits the inflammatory agents that accompany traumatic brain injury publication-title: Brain Res. doi: 10.1016/j.brainres.2005.05.004 – volume: 153 start-page: 3747 issue: 8 year: 2012 ident: 10.1016/j.yhbeh.2013.06.009_bb0385 article-title: Progesterone receptors: a key for neuroprotection in experimental stroke publication-title: Endocrinology doi: 10.1210/en.2012-1138 – volume: 108 start-page: 624 year: 1994 ident: 10.1016/j.yhbeh.2013.06.009_bb0300 article-title: Relationship between circadian changes in spontaneous motor activity and dorsal versus ventral striatal dopamine neurotransmission assessed with on-line microdialysis publication-title: Behav. Neurosci. doi: 10.1037/0735-7044.108.3.624 – volume: 6 start-page: e29354 issue: 12 year: 2011 ident: 10.1016/j.yhbeh.2013.06.009_bb0390 article-title: Vitamin D3 deficiency differentially affects functional and disease outcomes in the G93A mouse model of amyotrophic lateral sclerosis publication-title: PLoS One doi: 10.1371/journal.pone.0029354 – volume: 67 start-page: 78 year: 2013 ident: 10.1016/j.yhbeh.2013.06.009_bb0360 article-title: Combination treatment with progesterone and vitamin D hormone is more effective than monotherapy in ischemic stroke: the role of BDNF/TrkB/Erk1/2 signaling in neuroprotection publication-title: Neuropharmacology doi: 10.1016/j.neuropharm.2012.10.004 – volume: 8 start-page: 42 year: 2011 ident: 10.1016/j.yhbeh.2013.06.009_bb0215 article-title: Genomic profile of Toll-like receptor pathways in traumatically brain-injured mice: effect of exogenous progesterone publication-title: J. Neuroinflammation doi: 10.1186/1742-2094-8-42 – volume: 35 start-page: 134 issue: 1 year: 2004 ident: 10.1016/j.yhbeh.2013.06.009_bb0285 article-title: Differential skeletal responses of hindlimb unloaded rats on a vitamin D-deficient diet to 1,25-dihydroxyvitamin D3 and its analog, seocalcitol (EB1089) publication-title: Bone doi: 10.1016/j.bone.2004.02.014 – volume: 38 start-page: 234 year: 2000 ident: 10.1016/j.yhbeh.2013.06.009_bb0075 article-title: Acute administration of estrogen and progesterone impairs the acquisition of the spatial Morris water maze in ovariectomized rats publication-title: Horm. Behav. doi: 10.1006/hbeh.2000.1626 – volume: 37 start-page: 1896 issue: 11 year: 2012 ident: 10.1016/j.yhbeh.2013.06.009_bb0150 article-title: The impact of progesterone on memory consolidation of threatening images in women publication-title: Psychoneuroendocrinology doi: 10.1016/j.psyneuen.2012.03.026 – volume: 80 start-page: 1706S issue: 6 Suppl. year: 2004 ident: 10.1016/j.yhbeh.2013.06.009_bb0190 article-title: Functional indices of vitamin D status and ramifications of vitamin D deficiency publication-title: Am. J. Clin. Nutr. doi: 10.1093/ajcn/80.6.1706S – volume: 24 start-page: 232 issue: 2 year: 2007 ident: 10.1016/j.yhbeh.2013.06.009_bb0255 article-title: Prognosis and clinical trial design in traumatic brain injury: the Impact study publication-title: J. Neurotrauma doi: 10.1089/neu.2006.0024 – reference: 12009507 - Neurobiol Aging. 2002 Jul-Aug;23(4):579-88 – reference: 20079764 - Behav Brain Res. 2010 Apr 2;208(2):603-8 – reference: 10619486 - Neuroscience. 2000;95(1):293-307 – reference: 22216257 - PLoS One. 2011;6(12):e29354 – reference: 23030803 - J Neurotrauma. 2012 Nov 20;29(17):2716-21 – reference: 11104641 - Horm Behav. 2000 Dec;38(4):234-42 – reference: 19482377 - Neurobiol Aging. 2011 May;32(5):864-74 – reference: 22408173 - Endocrinology. 2012 May;153(5):2420-35 – reference: 23657707 - QJM. 2013 Sep;106(9):809-21 – reference: 17276138 - Trends Immunol. 2007 Mar;28(3):138-45 – reference: 8020109 - Cell Motil Cytoskeleton. 1994;27(3):234-47 – reference: 19331514 - J Neurotrauma. 2009 Jun;26(6):925-39 – reference: 7917055 - Behav Neurosci. 1994 Jun;108(3):624-35 – reference: 11744095 - Brain Res Brain Res Rev. 2001 Nov;37(1-3):301-12 – reference: 15992330 - Med J Aust. 2005 Jul 4;183(1):10-2 – reference: 16797538 - Exp Neurol. 2006 Aug;200(2):378-85 – reference: 21549006 - J Neuroinflammation. 2011;8:42 – reference: 22627988 - Stroke. 2012 Aug;43(8):2163-7 – reference: 20126570 - Acta Histochem Cytochem. 2009 Dec 29;42(6):171-9 – reference: 19355896 - Curr Med Chem. 2009;16(11):1418-25 – reference: 17435754 - Nat Neurosci. 2007 May;10(5):608-14 – reference: 11485234 - Neurosurg Rev. 2001 Jul;24(2-3):127-30 – reference: 7777133 - Neurobiol Aging. 1995 Mar-Apr;16(2):149-60 – reference: 17375987 - J Neurotrauma. 2007 Feb;24(2):232-8 – reference: 15585791 - Am J Clin Nutr. 2004 Dec;80(6 Suppl):1706S-9S – reference: 18852350 - Arch Neurol. 2008 Oct;65(10):1348-52 – reference: 2682316 - Neurobiol Aging. 1989 Jul-Aug;10(4):347-52 – reference: 10712861 - Horm Behav. 2000 Feb;37(1):86-95 – reference: 15922058 - Behav Brain Res. 2005 Jun 20;161(2):306-12 – reference: 17714831 - Neurobiol Aging. 2009 Mar;30(3):466-73 – reference: 15932748 - Brain Res. 2005 Jul 5;1049(1):112-9 – reference: 22504305 - Horm Behav. 2013 Feb;63(2):267-77 – reference: 16179538 - Ann N Y Acad Sci. 2005 Aug;1053:319-29 – reference: 21044614 - Brain Res. 2011 Mar 16;1379:149-63 – reference: 15957143 - Am J Kidney Dis. 2005 Jun;45(6):1119-21 – reference: 2569170 - Neurobiol Aging. 1989 Jan-Feb;10(1):31-43 – reference: 22570859 - Horm Behav. 2012 Apr;61(4):642-51 – reference: 18056830 - FASEB J. 2008 Apr;22(4):982-1001 – reference: 22442173 - Stroke. 2012 Jun;43(6):1470-7 – reference: 21403017 - Arch Neurol. 2011 Mar;68(3):314-9 – reference: 22635678 - Endocrinology. 2012 Aug;153(8):3747-57 – reference: 9046563 - Annu Rev Psychol. 1997;48:339-70 – reference: 20410196 - Endocrinology. 2010 Jun;151(6):2713-22 – reference: 9757832 - Trends Biochem Sci. 1998 Aug;23(8):307-11 – reference: 22534403 - Psychoneuroendocrinology. 2012 Nov;37(11):1896-900 – reference: 14735112 - Nat Rev Neurosci. 2004 Feb;5(2):87-96 – reference: 19468818 - J Neural Transm (Vienna). 2009 Jul;116(7):905-11 – reference: 22796576 - Front Neuroendocrinol. 2013 Jan;34(1):47-64 – reference: 19603099 - Mol Med. 2009 Sep-Oct;15(9-10):328-36 – reference: 21335669 - Restor Neurol Neurosci. 2011;29(1):61-71 – reference: 23154302 - Neuropharmacology. 2013 Apr;67:78-87 – reference: 18572204 - Neuropharmacology. 2008 Aug;55(2):127-38 – reference: 11295155 - Mutat Res. 2001 Apr 18;475(1-2):69-87 – reference: 14592674 - Pharmacol Biochem Behav. 2003 Sep;76(2):231-42 – reference: 23336971 - Neuropathol Appl Neurobiol. 2013 Aug;39(5):458-84 – reference: 18579197 - Mol Aspects Med. 2008 Dec;29(6):415-22 – reference: 12580336 - Neuroscientist. 2003 Feb;9(1):10-22 – reference: 17892409 - J Neurotrauma. 2007 Sep;24(9):1475-86 – reference: 15207749 - Bone. 2004 Jul;35(1):134-43 – reference: 21703565 - PM R. 2011 Jun;3(6 Suppl 1):S100-10 – reference: 22903611 - Endocrinology. 2012 Oct;153(10):4874-82 – reference: 21851230 - J Neurotrauma. 2013 Jan 1;30(1):47-54 – reference: 11150325 - J Neurosci. 2001 Jan 1;21(1):98-108 – reference: 23098125 - J Neuroinflammation. 2012;9:244 – reference: 23419893 - Brain Res. 2013 Jun 13;1514:40-9 – reference: 17612919 - Br J Neurosurg. 2007 Jun;21(3):281-7 – reference: 17230473 - Mov Disord. 2007 Mar 15;22(4):461-8 – reference: 19794127 - Neurology. 2010 Jan 5;74(1):27-32 – reference: 15781154 - Neurosci Lett. 2005 Apr 22;378(3):176-80 – reference: 17482806 - J Steroid Biochem Mol Biol. 2007 May;104(3-5):274-80 |
| SSID | ssj0011544 |
| Score | 2.3211768 |
| Snippet | Progesterone (PROG) and vitamin D hormone (VDH) have both shown promise in treating traumatic brain injury (TBI). Both modulate apoptosis, inflammation,... |
| SourceID | pubmedcentral proquest pubmed pascalfrancis crossref elsevier |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 527 |
| SubjectTerms | Adult and adolescent clinical studies Aging Aging - drug effects Aging - physiology Animal cognition Animal memory Animals Behavioral psychophysiology Biological and medical sciences Brain damage Brain Injuries - complications Brain Injuries - drug therapy Combination treatments Cytoprotection - drug effects Disease Models, Animal Drug Evaluation, Preclinical Drug therapy Functional repair Fundamental and applied biological sciences. Psychology Hormones and behavior Injuries of the nervous system and the skull. Diseases due to physical agents Male Maze Learning - drug effects Medical sciences Neuroprotective Agents - administration & dosage Organic mental disorders. Neuropsychology Progesterone Progesterone - administration & dosage Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Psychopathology. Psychiatry Rats Rats, Sprague-Dawley Rodents Swimming Traumas. Diseases due to physical agents Traumatic brain injury Vitamin D Vitamin D - administration & dosage Vitamin D deficiency Vitamin D Deficiency - complications Vitamin D Deficiency - drug therapy Vitamin D3 hormone |
| Title | Progesterone and vitamin D: Improvement after traumatic brain injury in middle-aged rats |
| URI | https://dx.doi.org/10.1016/j.yhbeh.2013.06.009 https://www.ncbi.nlm.nih.gov/pubmed/23896206 https://www.proquest.com/docview/1437317219 https://www.proquest.com/docview/1556990079 https://www.proquest.com/docview/1438573348 https://pubmed.ncbi.nlm.nih.gov/PMC3833454 |
| Volume | 64 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1ba9RAFD6UCiKIaOslti4jiE-uTeaa-LaslvXSUsTCvoVMMmlT3OzS3S30xd_uOZOLrix98CmQmWSSOdc5c-Y7AG-ULspEuZA8t4JCN2qYWI1yVWqTJ9bmUtBB4ZNTPTmXX6ZqugPj7iwMpVW2ur_R6V5bt3eO2tk8WlQVnfGNCG5tShsy6McQ7LaUhrj8_a8-zcOjzTTaOB5S7w55yOd43V5aRzsSkfAgnpSVuN06PVxkS5yzsil2sc0b_Tep8i8rdfwYHrXuJRs1f_AEdly9B_ujGpfWs1v2lvmETx9J34P7J-2--j5Mz67nFx4zYV47ltUFu6lW2ayq2ccPrIk7-DAi8yXFGY689lCvzFKFCVbVV0gavLCZj3cMUUkVDHlr-RTOjz_9GE-Gbc2FYY6-1App5DjKpCpVUqich1a72GpOMHFah5nSJsnRpvPCCi2QkIVzkcmdiWwhy0yV4hns1vipL4DpUJgkEtqGHDtGtDSUips8ziR3spAB8G6u07wFJKe6GD_TLvPsKvUESolAqc-_SwJ41z-0aPA47u6uOyKmG2yVosW4-8HBBsn7wbhBBycxKoDDjgfSVuyXuI4SRtCiOtnerJRG6x8abH7dN6M80yZNVrv52r8iJoxKGQfwvOGoP2Ojd6l5qAMwG7zWdyCs8M2Wurr0mOEixlcq-fJ_5-MAHnBfCIRSHw9hd3W9dq_QHVvZgZe3Adwbjb9_O6Pr56-T099YeDWm |
| linkProvider | Elsevier |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3db9MwED-NTgIkhGDjIzCGkRBPREvs2E54qwZTx9aKh03qWxQnzpaJptXaIu2_5875gKJqDzxFiu249X34fHf-HcBHqYoykTYgy60g1430E6NQrkql88SYPBJ0UXg8UaPL6PtUTnfguLsLQ2mVre5vdLrT1u2bo3Y1jxZVRXd8Q4Jbm1JABu0Y9QB2CZ1KDmB3eHo2mvTBBAKcaRRy7NOADnzIpXndXRtLQYlQOBxPSkzcvkE9WWRLXLayqXexzSD9N6_yr43q5Bk8bS1MNmz-xHPYsfUe7A9rPF3P7tgn5nI-nTN9Dx6O29D6Pkx_3M6vHGzCvLYsqwv2q1pls6pmX7-wxvXgPInMVRVnOPPaob0yQ0UmWFXfIHXwwWbO5eGjnioYstfyBVyefLs4Hvlt2QU_R3NqhWSyHMVSljIpZM4Do2xsFCekOKWCTCqd5Lit88IIJZCWhbWhzq0OTRGVmSzFSxjU-FNfA1OB0EkolAk4dgzpdBhJrvM4i7iNisgD3q11mreY5FQa42faJZ_dpI5AKREodSl4iQef-0GLBpLj_u6qI2K6wVkpbhr3DzzcIHk_Gddo4yRaenDQ8UDaSv4Sj1JCCzpXJ9ubpVRoAAQamz_0zSjSFKfJajtfu0_EBFMZxR68ajjqz9xoYCoeKA_0Bq_1HQgufLOlrq4dbLiI8ZMyevO_6_EeHo0uxufp-enk7C085q4uCGVCHsBgdbu279A6W5nDVvp-AySBNsI |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Progesterone+and+vitamin+D%3A+Improvement+after+traumatic+brain+injury+in+middle-aged+rats&rft.jtitle=Hormones+and+behavior&rft.au=Tang%2C+Huiling&rft.au=Hua%2C+Fang&rft.au=Wang%2C+Jun&rft.au=Sayeed%2C+Iqbal&rft.date=2013-08-01&rft.issn=0018-506X&rft.volume=64&rft.issue=3&rft.spage=527&rft.epage=538&rft_id=info:doi/10.1016%2Fj.yhbeh.2013.06.009&rft.externalDBID=n%2Fa&rft.externalDocID=10_1016_j_yhbeh_2013_06_009 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0018-506X&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0018-506X&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0018-506X&client=summon |