A trans-acting sRNA SaaS targeting hilD, cheA and csgA to inhibit biofilm formation of S. Enteritidis

• Published in: Journal of advanced research Vol. 71; pp. 127 - 139
• Main Authors: Lyu, Chongyang, Hu, Haijing, Cai, Linlin, He, Shuwen, Xu, Xinglian, Zhou, Guanghong, Wang, Huhu
• Format: Journal Article
• Language: English
• Published: Egypt Elsevier B.V 01.05.2025; Elsevier
• Subjects: Agricultural Science; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Biofilm; Biofilms - growth & development; EPS; Flagellar; Gene Expression Regulation, Bacterial; RNA, Bacterial - genetics; RNA, Small Untranslated - genetics; RNA, Small Untranslated - metabolism; Salmonella Enteritidis; Salmonella enteritidis - genetics; Salmonella enteritidis - physiology; sRNA; Target mRNAs; Biofilm; EPS; Flagellar; Target mRNAs; Salmonella Enteritidis; sRNA

[Display omitted] •sRNA SaaS inhibits biofilm formation by interacting with target mRNA (hilD, cheA, and csgA).•The space morphological structure of biofilm in polystyrene microplates was firstly obtained by using CLSM.•Transcriptomics and proteomics were applied to analysis the changes of gene expr...