An important role for the activation peptide domain in controlling factor IX levels in the blood of haemophilia B mice - Begbie, Megan E; Mamdani, Asif; Gataiance, Sharon; Eltringham-Smith, Louise J; Bhakta, Varsha; Hortelano, Gonzalo; Sheffield, William P (Thrombosis and haemostasis, 2005)
Keywords: Amino Acid Motifs; Animals; Antithrombins - metabolism; Area Under Curve; Cell Line; Disease Models, Animal; Factor IX - chemistry; Factor IX - genetics; Factor IX - pharmacokinetics; Factor Xa - metabolism; Glycosylation; Hemophilia B - blood; Hemophilia B - drug therapy; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Partial Thromboplastin Time; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Proteins - pharmacokinetics; Tissue Distribution; Transfection